HsaINT0059121 @ hg38
Intron Retention
Gene
ENSG00000131187 | F12
Description
coagulation factor XII [Source:HGNC Symbol;Acc:HGNC:3530]
Coordinates
chr5:177403481-177404090:-
Coord C1 exon
chr5:177403859-177404090
Coord A exon
chr5:177403618-177403858
Coord C2 exon
chr5:177403481-177403617
Length
241 bp
Sequences
Splice sites
5' ss Seq
CCGGCGAGT
5' ss Score
3.14
3' ss Seq
CTCCCCTACCCCCCCCGCAGGCC
3' ss Score
11.59
Exon sequences
Seq C1 exon
CCTTGCCGGCGAAGCGGGAGCAGCCGCCTTCCCTGACCAGGAACGGCCCACTGAGCTGCGGGCAGCGGCTCCGCAAGAGTCTGTCTTCGATGACCCGCGTCGTTGGCGGGCTGGTGGCGCTACGCGGGGCGCACCCCTACATCGCCGCGCTGTACTGGGGCCACAGTTTCTGCGCCGGCAGCCTCATCGCCCCCTGCTGGGTGCTGACGGCCGCTCACTGCCTGCAGGACCG
Seq A exon
GCGAGTACCCGCCCGCCCAGAGCCGCCCCAGGGGCCGCGGCTCCTCCGTCTCCCAGCGCAGCTTCCACGCTGCACCCGAACCCGTGCCCTACCTTCTCCCGCCCCACCCTTCTTTCCACGCCCCTCCGGAGCTCCCGGGGAGGAAGCTGGAACACGGGATTGGGGTTCGGGAGCAGGGGGCTTCCCCAGAACGCTTGTGGCCAGGTCTGAGAGCGCTGCCTCTCCCCTACCCCCCCCGCAG
Seq C2 exon
GCCCGCACCCGAGGATCTGACGGTGGTGCTCGGCCAGGAACGCCGTAACCACAGCTGTGAGCCGTGCCAGACGTTGGCCGTGCGCTCCTACCGCTTGCACGAGGCCTTCTCGCCCGTCAGCTACCAGCACGACCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000131187:ENST00000253496:10
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.218 A=NA C2=0.064
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PU(18.6=56.4)
A:
NA
C2:
PF0008921=Trypsin=FE(19.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTCCGCAAGAGTCTGTCTTC
R:
CAGGTCGTGCTGGTAGCTGA
Band lengths:
301-542
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development