HsaINT0062652 @ hg19
Intron Retention
Gene
ENSG00000099364 | FBXL19
Description
F-box and leucine-rich repeat protein 19 [Source:HGNC Symbol;Acc:25300]
Coordinates
chr16:30939788-30941905:+
Coord C1 exon
chr16:30939788-30939949
Coord A exon
chr16:30939950-30941393
Coord C2 exon
chr16:30941394-30941905
Length
1444 bp
Sequences
Splice sites
5' ss Seq
GAGGTGTGC
5' ss Score
5.35
3' ss Seq
TCAACCCTGTCTCCCTGCAGAAA
3' ss Score
11.94
Exon sequences
Seq C1 exon
GTGAAAGGAGGCCGAGAGAGGCACCTGAAGAAGGTGGGTGGAGACGCCTGCCTCCTCCGAGGATCGGACCCAGGCGGCCCGGGCCTGCTGCCCCCCAGGGTTCTGAATCCGAGCCAGGCTTTCTCATCCTGCCACCCTGGGCTCCCTCCCGAGAACTGGGAG
Seq A exon
GTGTGCCGGGGACCTCCTCCCTCCCCTTCCCACCTTCCCTTGCCCCACCCTTCACCCTGGAGCCCAAGACCTGTCCCTTCCTGCTCACCTTGTTCTGCCCCAGCCCCACTTGGCCACGGTGGGTGTCCGGACACCTGGGATGAGTTGGGTGGGAGGGTGGGTTGAGTCCAGGCCACAGGAGCCCCTGACTTCCCAAAAACCCTTAGGGCTCATCTGACCTACTTGCCTCATCTTTCCAAGCCTTACAGGGGAGAGAACTGAGTTCAAATTTCTGTCCGACCGTTTACTCTTTGTATGATCCTAGCAGCTTGTCAGCCACCCTGAGCCTTAGTTTCTTTATCCATGTAGTGGAGATGCTGCTGCCTGCCTTGCCCCCTTATCCCGCAGAAGTGTATAAGTCTTACGAGGTTCTGAAAGGCAATGAGCTTTGTAAGCTATAAAATTTACCCAGATTGAAGGGAAATAAGGCCCAGAGAGGTTTGAAGACTTGTCCAAGTCACACAGTAAAGCCAGAATTGAGGTATTACTTGGCACGGACACTCAACACAGGAGTCCGCCTGATTGGGTCCAAATCCTGCCTCTGCTGTTTGTCAGTTTGTAACCTTGGACAAGTCACTTTGTGCCTTTAAGCCTCGGTTTCCTCATGTCTGAAAAGAGTGGCCCAGGTCACCACTGTGTTAGAATACTGTGAGGATGGAATGAGTCAGCCGATGCGGGGTGCTGCTCGTGGGGCCAATCACTGTTACCCTCAGTTGATAGACAGACGCCTGCTCCAGCTGGTCCGTGTAGTGGATGATGAAGCAGGGGCTTCCCACAGCCATCCAGAGTTGAGGGCAAGCCAGGATTCAAAGCAGGGTCTCTCATTTCTCCATTCCCTACTGCTTTTGGAACTGCCTAAGCCATGCAAACCCATAAGGGCTGGAAATTATTTTATTTTATTTTATTTTTGAGACAGAGTCTCGCTCTGTCGCCCGTACTGGAGTGCAGTGGCGTGATCTCGGCCCGCTGAAACCTCCACCTCCCAGGTTGAAGCAATTCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCTTGTGCCACCATGCCCAGTTTATTTTTGTATTTTTAGTAGAGACAGGGTTTCACTATGTTGGCCAGGATGGTCTCGATCTCTTGACCTCGTGATCCTCCCGCCTCGGCCTCCCAGAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCCGGCTGGAAATTATTTTAATTAGCACTCTTCTGTTACCAATAAGAAAACTGAGGCCCAGGGCCTGGCAGTGGCTTTAGCAAGGTCTCTCACTGTCCGGAGCAGAGCCAGGGCTGGAACTCAGGACTGTCCCTCGGGCTGTTCATCCCCTGGTGACTCCTCGGGGTAGGGGGGTGGGAAAATGTATCCCAGGCCCTAGAACAGCATCAACCCTGTCTCCCTGCAG
Seq C2 exon
AAACCAAAGCCGCCTTTGGCCTCTGCAGAGGGCCCAGCGGTGCCGTCCCCGTCCCCGCAGAGGGAGAAGCTAGAGCGTTTCAAGCGGATGTGCCAGCTGCTGGAACGGGTGCCTGACACCTCCTCTTCCTCCTCGGACTCAGACTCCGACTCCGACTCTTCGGGCACATCGCTGAGTGAGGACGAAGCCCCCGGCGAGGCCCGGAATGGGCGACGGCCAGCCCGGGGCAGCTCTGGCGAGAAGGAGAACCGTGGGGGGCGGCGGGCTGTGCGCCCTGGCAGTGGGGGGCCCCTACTCAGCTGGCCCCTGGGCCCAGCCCCACCACCCCGGCCTCCACAGCTGGAGCGGCACGTGGTGCGGCCCCCGCCTCGAAGCCCTGAGCCCGACACACTCCCCTTGGCTGCTGGATCCGACCACCCCCTGCCCCGGGCCGCCTGGCTTCGCGTCTTCCAGCACCTCGGGCCGCGGGAGCTGTGTATCTGCATGCGAGTCTGCCGAACTTGGAGCCGCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000099364-FBXL19:NM_001099784:6
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=NA C2=0.809
Domain overlap (PFAM):
C1:
PF133971=DUF4109=FE(21.3=100)
A:
NA
C2:
PF133971=DUF4109=PD(12.8=3.5),PF0064628=F-box=PU(70.5=18.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGAAAGGAGGCCGAGAGAGG
R:
CTTCGTCCTCACTCAGCGATG
Band lengths:
348-1792
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)