HsaINT0065110 @ hg19
Intron Retention
Gene
ENSG00000184922 | FMNL1
Description
formin-like 1 [Source:HGNC Symbol;Acc:1212]
Coordinates
chr17:43322620-43323100:+
Coord C1 exon
chr17:43322620-43322783
Coord A exon
chr17:43322784-43322998
Coord C2 exon
chr17:43322999-43323100
Length
215 bp
Sequences
Splice sites
5' ss Seq
CAGGTGCGC
5' ss Score
9.1
3' ss Seq
CTGACAGGCTGTGCCCACAGGAG
3' ss Score
5.96
Exon sequences
Seq C1 exon
TGTCCCTGGACAGTGTCCTGGCGGACGTGCGCTCCCTGCAGCGAGGCCTAGAGTTGACACAGAGAGAGTTTGTGCGGCAGGATGACTGCATGGTGCTCAAGGAGTTCCTGAGGGCCAACTCGCCCACCATGGACAAGCTGCTGGCAGACAGCAAGACGGCTCAG
Seq A exon
GTGCGCCAGGGCTGGCCTCACCTGGAGGTGGGGCATGTAGGAGCACTAGATAGCACAGCCTGGAGGGGTGTGGCCGTAGCTGGGACCCCTTGGGGGGATGCAGCAGGAATGAGGGGCCACCCTGCCTGGGAGGAGCTCAGATCAGGTGGCCAGTGTCCTGAGGGGTACAGGCTGTGAGAGGTCTAAGCTGGGGGGCTGACAGGCTGTGCCCACAG
Seq C2 exon
GAGGCCTTTGAGTCTGTGGTGGAGTACTTCGGAGAGAACCCCAAGACCACATCCCCAGGCCTGTTCTTCTCCCTCTTTAGCCGCTTCATTAAGGCCTACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000184922-FMNL1:NM_005892:22
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.055 A=NA C2=0.018
Domain overlap (PFAM):
C1:
PF0218118=FH2=FE(14.7=100)
A:
NA
C2:
PF0218118=FH2=FE(10.1=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGCAGCGAGGCCTAGAGTT
R:
TGTAGGCCTTAATGAAGCGGC
Band lengths:
229-444
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)