HsaINT0065124 @ hg19
Intron Retention
Gene
ENSG00000157827 | FMNL2
Description
formin-like 2 [Source:HGNC Symbol;Acc:18267]
Coordinates
chr2:153468009-153471514:+
Coord C1 exon
chr2:153468009-153468119
Coord A exon
chr2:153468120-153471364
Coord C2 exon
chr2:153471365-153471514
Length
3245 bp
Sequences
Splice sites
5' ss Seq
GACGTGAGT
5' ss Score
9.22
3' ss Seq
TCTCCTATTCTGGTTTTTAGAAG
3' ss Score
7.26
Exon sequences
Seq C1 exon
GTGGCTTCTATGCAGTTTATTAATATTGTAGTCCATTCAGTAGAAGATATGAATTTCAGAGTTCACCTGCAGTATGAATTTACCAAATTAGGCCTGGACGAATACTTGGAC
Seq A exon
GTGAGTATAGCTGTGACCTTTGGCTCCAATATAAGAATTGACTTATTATTGCCTGCCCTCAAAGGTACGCTTCCATAGCAGCTAAAGAATGCCTAAAGCTCTATGCAGTCAACTACTGTAGTGCTAGTTAAAGGGAACTGAGCTGAGTGATGTACTCTGCCAGAGATGCTGGATTCTTGCAGGGCTCCTGGGATCTCAGGTCATCTTCTGCTAGCAGCCTTTTAGTACGGGAGTCAGATAACCTCTTGCAGCCTTGCTGCAGCTTTCCTCTCCTTTTGAGCTTCATCTGGGTCAAGTCTCATTGCATCCTTCATCTGGGCTATTGGGCAATTTGTGTTCTTGGTTACTCCGGGGACCCCATCTGGGCAGAGAAAGTCAAGCCAAGACTGTAGAGTGATGAGTCAGTGCTTAGAGCATAAAAAAAAAATAATGAGGAAATGGACACCAGAGACTTCCTCCTGAAGCTGCTAAATTCTGCTTCAAGTGTTTGTGGCTTTAGAAGTTCCACTTTTAGTTCTTAGGAGAAGGAGGTTTAAAGTTTCCCTTTTTCTCACTCCCTTGCAGAAGAGTTTAGCCAGTTCCCTGAAGTTCTTCAGTTAAGAAACAGAAACTTGTGAAAATCAGAAATGGTCTTGAAAAGGCTGATGGCTCACACCTGTAATTCCAGCACTTTGGGAGGCTGAGGTGGAGGATCACTTGAGCCTAGGAGTTCAAGACCAGGCTAGGCAACATAGTGAGACCCCATCTATACAAAACACCAAAAAATTAGCCAGGTGTGGTGGTATGTGCCCGTGGCCCCAGCTGCTTGGGAAGCTGAAGTGGGGGGATCATTGGAGTCCAGGATTTCTAGGCTGCAACAAGCTGTGATTGCACCACTGCACTCCAGCTTGGGTGGCAGAGCGAGACCCTGTGTCTAAAACGGAAAAGAAGTGGACCTGAGGATCCAGGCAGTTTTGTTTTCCCTTTTGTATAGGAATGGTCTAGTGATAGAGCAAGAATTGTTGACCTCAATTTCCTTCCTTTTTTTTGAGACAGGGTTTCACTTTGTCAACCAGGCTGGAGTGCAGTGGTGCAATCTTGGCTCACTGCAACCTCTGCTTCCTGGGTTCAAGCGATTCTCATGCCTCAGCCTCCTGAATAGCTGGGATTACAGGCACTATGCCTGGCTAATTTTTGTATTTTTAGTAGAGACTGGGTTTCACCATGTTGGCTAGGCTAGTCTCATACTCCTGCCTCAAGTAATGCACCCAGCCGGTGACCTGAATTTCAAGCCTGTTTCCAGCTGTGAAGAATATAGAAGTACTTCCTTTGGGCATCTCAGGAATTCAGTTGCCCATCTTTGTTAGAGATAAACCCAAGGGATTGCACAGACTGTACCCTCAGTTTATTAGGAGACGGAATCACAGAGGTGGTTACTCTCAACCTGAAGGCCTTGCTTCCTAGACTGGCTGGGCTGCCCTTGAATAGATGGGCCTACTGTTGTCTAAAGACTACTCAGGGAGAGGCGTAATAGATTTCCATTAAAATGTTGTTTGAATTGCTTTCCTTTTTATTTAAAGGCTCATTTATATCACTGGCAGAATATTGTACAGAAAGACTCTTTCTTACTTTGAGATCAAGGTTTGTCTATCCCTTTTTCTCCTATGCTCTAAAAGTATCAGTATTTGAACAAAAATTGGATGTATAAATTCCTAGCGGTGTTTTGGGTTTGGTTTTGTGGTGTCTGAGCAGAGCTTGTTTATGCTGTAGAATATAACGGCAGGTACCCACTTATCACTGAACACCTGTTATTCATTGTGAATCTCATGAAAAATCCCATTAAGCTGCTTCTCCTTTTGTTCTAGCCTTTGCCCTTATTTAGAAGCCATTCTCACTTGTGACTCATAAATGAAAACAGAACACTCTCTCTTCAGAATAAGCTGTATTGTAGAATTCCAGATTAAACCTAGGGGAAAATCCATTTTTCTGAAAATTTATGTAGAGTGGAATTTCTCTTAAAAATGTAAGATTTTTTGTCAAAACTCTGTATTTCTTTAACTTCATCATGTGTTGACTCTGGAACCTAATAGAGGTGGTTAGAAGAGTAATGTAAATGTATGCTATATAAATGCTTCACTAGTTTACAAAAACCCAGCCTTGTAAGTAGCCATTGATTTGTTCAATAAATGTTGATTGGCATCATCCATGCACCAGGTATTATTCTAATCACTCATCTGTTCCCCAGGGAAAGTCATGACTTATGTTACTTGTAGGGAAGATTCACTGATTTATTTGACCTCTAATTTCCAGAGCTAGCTGAGTCCCTGCAGGATGCCTAGTTTGGGAGGCAGTGAATTGGGGAAAGCTTTCTGATCTGCCTTGGGGAGCCCTGAGCTGTTCATGCTGTATACTGACTTAGGGAGGGATGTGTGGAGGTTGGGCTCTAGCAATTTGTGCTAAAATAATCCCCAAGGCTAAGTATAAACTCTGTCAGTGTCTGCCCCACCTCTCGCCTAACCTTCTTCCCCTACTGGAACCACTGTAACTAACCAGGTAAGATACCAAACACTCCAGTCTTTTCCACTACACAGATACCCCTCAGGTTTTATGTGGCCATGACTATAACCTGTTAAAGCTGCTTTTAATTTTTCTGTTGTCCCAATTTCATGTATATCAAAATGTTTTACATAGGAATATAACTACATGGGGCAGTAAGGATTTGGGGGAAAATGTGTGTGCATTTGGGAGAGCGTATTCACCCGAAAGTCATCTGATGATACTGCTTAGGCAGTCACTCCATAATTCTCTTAAGGAAGATGACATGTTAAGCTCTCTTGGAAAGGGCTGGACTATTTGTCGAAAAGAAAACACATAGACTGGCTGGGTGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGCCGGGTGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCCAACAGGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCGCGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGACACGAGAATCGCTTGAACCCAGGAGGTGAAGGTTGCAGTGAGCTGAAATCATACCATTCCACTCCAGCCTGGGTGACAGAGTGAAACTCCATCTCAAAACAAAACAAAACAAAACAAAAAACAAAAAAGACAGACTCTTAGGAAATGATGTTCTATTTCCATAGATGAGCTAACACCACGTTCTCTCCTATTCTGGTTTTTAG
Seq C2 exon
AAGCTGAAACACACTGAGAGTGACAAGCTTCAAGTCCAGATCCAGGCTTACCTGGACAATGTTTTTGATGTAGGAGCTCTACTGGAAGATGCTGAAACTAAGAATGCTGCCTTGGAGAGGGTGGAAGAACTGGAAGAAAACATTTCTCAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157827-FMNL2:NM_052905:11
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.080
Domain overlap (PFAM):
C1:
PF0636711=Drf_FH3=FE(17.6=100),PF139351=Ead_Ea22=PU(17.4=73.0),PF061486=COG2=FE(18.9=100)
A:
NA
C2:
PF0636711=Drf_FH3=FE(23.9=100),PF139351=Ead_Ea22=FE(31.6=100),PF051307=FlgN=PU(47.3=86.0),PF061486=COG2=FE(25.8=100),PF053358=DUF745=PU(19.4=38.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)