HsaINT0065145 @ hg19
Intron Retention
Gene
ENSG00000157827 | FMNL2
Description
formin-like 2 [Source:HGNC Symbol;Acc:18267]
Coordinates
chr2:153435402-153437563:+
Coord C1 exon
chr2:153435402-153435478
Coord A exon
chr2:153435479-153437469
Coord C2 exon
chr2:153437470-153437563
Length
1991 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGC
5' ss Score
9.88
3' ss Seq
TCTTCTTCTTGTTTTGGCAGAAC
3' ss Score
8.78
Exon sequences
Seq C1 exon
TATGGTTTCAACATGGTCATGTCTCATCCACACGCTGTCAATGAGATTGCACTAAGCCTGAACAACAAGAATCCCAG
Seq A exon
GTAAGCTGCTTTTGTAGTACGCAAGTCTAAATCTATCTAGAGAAAACAGAGGGCTAGTCAACACTTAACCAAGTTTGACTTTGGAAACTTTCAAGTGTTAATCTCTGAAATAAGATTGGCTATAAACTCTTTGGCTGTGTAAGAATTTTTCCTTTTAGCCAAGTTACATTCTTAGATGGGCCAGAGTTGAGCAACTGGTGACAATTCTAGCCCTTCACTGTTCTCCTCAAGCTTTTGTTCTTTTGAGGCCTGGTTTCCAGCATCCTTGCTGCTAAATTTGGAGAGGATCAGGTTGCCAGGACTCGGGGGCCAGGAGAGTCTTGATAAAGATTTACGTATATCAGTTATTGCTGGAAGCTAGCTAAAACCACCATCCTTCGTCTACACTTCGCTTGATAACTTTACATATGTAGCTTTAATTACTGAACGAAAATAGAAAAATAATTGTAGTGGCCAGCCGCAGTGGCTCATGCCTGTAATCTCAGCACTTTGGGAGGCCGAGGCAGGCAGATCACCTGAGGTCAGGAGTTGCGACCAGCCTGGCTAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGCCAGACATGGTGGCACATGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGCTTGAACCCAGGAAGTGGAGGTTGCAGTGAGCCGAGATCGCACCGCTGCACTCCGGCCTGGGTGACAGGGCAAGACTCTGTCTCAAAAAATAAAGAAAGAAAGAAATAGAAAAATAAAATTGTATATGCAGATTTCCTTTCATATTCACCACCTTGTAAAGGCTAGCAGCAGATATAATTCACATCACACGTTAGTCGTAAAAGCCAGTCTTCATCAATTGTAGTTATTTTAATGTGCTTTCCATTTTGGTGAAGTATTCTGTACTTCAAATGTGCAATTCCTTTTCATCCAATACCTCTCTGTAGACAAAATATCTGAAAACTGTTAATTCAAAAATCTGTTTATAAATTAGCCATTTCTGATTTGGAAAATGCAACACGAACTATCAAGTCCTCTTTACTGAATATTATTCTTTCAAACTTCCCCTGATTAAACCTTTTGCGACTGTGCGATTCCTTCCTTCGTTTACTAGAGTCCTAAGTAGCCATGCTTCTGTGTCTCTGCCTTCTACTACAGGGAAGACATTATTTTTTAAAAGACAATTGACATTGTGGAGTATCAGAACAGTTTTTGTTTAGAAGTTGGTGAAAGCTGTTATTCCAGAAAAAAAATGAAATACTTAAGTGGTCTTATGATTGAAGAAACAATGCTGTTTCTTTCTTGACATTGAATTTGAAAACTTAGAGTGTATCTCCATGTTCTCCTTCCAAAAATATTTCAGATTGAGTTTTATTTTCTTGAGTCAAAGAAAATATTCTTGTGTTAGTAAAGCTAGTAAAGCTGTAATCCAGCTCCTTCCAGTTGTCCTGCGTAGGAAGAAGAAAGGACAGAAACTTGTATTTTCGTGGGAGATTTATGGATCTGTCCCTACATGAGCAGATTTGAAATGTAGAACATGAGTTTCAGTTGATTTTGAACTTTTTTTTTTGCAAATGTTCTCTCACTGTCTCTAAAACCAGAGCAAATACTTAATCAATAGTTTGTTTTTCAGCATATTCCCATTCCCTTTGTTTTTAGCGTACCAGTAAACATTTTTCATCTGTATTGTACTGAGTCACCTGATGATAGGTCTAAGAGATTATTCTTCTCAGAACTAGTTTTCATTAGTGAGTGATTTGTCTTTTTGGTAAGTATACCTTCCAAATTTGCCATCTTAGACAAATCACATATGTAGTAGTCAGTAAAGGTTTAAAAATGTACTTTGATTAAACTGTACCTTAGTAAAATTTTTTAAAAATGTAAGGGCAAATGTTTTATTCTCATGTATCTTGGAAGGAAGAAACAGCTGACTCATCATGCCATTTTCACTGATTTGTGTTTTTCTTCTTCTTGTTTTGGCAG
Seq C2 exon
AACAAAAGCCCTTGTCTTAGAACTGTTGGCAGCCGTTTGTCTTGTCAGAGGCGGGCATGAAATCATTTTATCAGCATTTGATAACTTTAAAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157827-FMNL2:NM_052905:8
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.071 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF063718=Drf_GBD=FE(33.8=100)
A:
NA
C2:
PF063718=Drf_GBD=PD(18.7=43.8),PF0636711=Drf_FH3=PU(15.6=43.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)