HsaINT0065766 @ hg19
Intron Retention
Gene
ENSG00000136877 | FPGS
Description
folylpolyglutamate synthase [Source:HGNC Symbol;Acc:3824]
Coordinates
chr9:130573224-130576556:+
Coord C1 exon
chr9:130573224-130573290
Coord A exon
chr9:130573291-130575473
Coord C2 exon
chr9:130575474-130576556
Length
2183 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGA
5' ss Score
9.22
3' ss Seq
CCTTTCTCTGTGCCCCACAGACC
3' ss Score
11.32
Exon sequences
Seq C1 exon
CCCTGCCAGTTTGACTATGCCGTCTTCTGCCCTAACCTGACAGAGGTGTCATCCACAGGCAACGCAG
Seq A exon
GTGAGAGGTGACAGGCATGGCCCCTGGGGATGAGCAGGGGTCCCTGAGGTAGACAGTGGGGGCTTCCAAACTGGAGGTTTGGGGTAGGAAATAAATTTGTTTTACTGTGTAAGAACACTTTAGTGTACTTATACTCTTTTATACACCAAAGTATACTTTATTTAATTTTATTTTAAAAAATTTTTGGCTGGCCACGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGCAGATCACGAGGTCAGGAGATTGAGACCATCCTGGCTAACATGGTGAAACCCCGTCTCTACAAAAAAAAAATACAAAAAATTAGCCAGGCGTAGTGGTGGGTGCCTGTAGTCTCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGCGTGAACTCGGGAGGCGGAGCTGGCAGTGAGCCGAGATCGCGCCACTGCACTCTAGGTCTGGGCGACAGAGCGAGACTGTCTCAAAAAAAAAAAAAATTAATTTTTGAGACAGAGTCTCACTCTGTCCCCCAGGCTGGAATATAGTGGCACAATCTCAGCTCACTGCAACCTCTGCCTCCTAGGTTCAAATGATTCTCATGTCTCAGCCTCTGGAATAGCTGGGATTACAGGCGTGTGCCAACATGCCCAGCTAAGTTTTATATTTTTAGTAGAGACAGGGTTTCTCCATGTTGGCCAGGCTGGTGTCAAACTCCTGGCCTCAAATGATCCACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGTTGTGAGCCACCACGCCCAGCCAGCATTTTTTATTTTATATGAAATAGAGTAGAATAGAAAATACCAGTGTACGTTGCACAGAGTAAGGGTAGGTCCTGTTTGGTGAAGATTAGTCTGTTCCAGGCATATGTATAAGTATGTGAGTACTGAGTTGCAGTGTAAAATGTGTTTTTTACCATGTATCATGTTAAAAAAAGTTTGAAATAGTGTAAAAATTACAGATCCCAGGCTGGACTTGGTGGCTCACACCTATAATCCCAGCACTTTGGCAGGAGGATCGTTTGAGCTCAGGAGTTAAAAGCCAGACCTCATCTCTATAAAAAAAAATAGAAGAATTAGCCAGGTGTGGTGGTGTACACCCGTGGTCCTAGCTACTCAGGAGGCTGAAGTGGAAGGATCGCTTGAGCCTGGAAGGTGGAGGCTGCAGTGAGTCATGAAGTCGTGATTGCATCACTGCACTCCAGCCTGGGTGACAGAGCAAGACCCTGGACCCTCTCTAAAAATAAAAAATCTCCAGTCCTCACATCAGTCTGGTTGGGGAGAGTTCTGGAATCTGCATTTTTTTTTTTTTTTTCTTGAGACAGTCTCGTTCTGTCACTCAGGCTGCCCAGGCTGGAGTGCAGTGGTGCCATCTCGGCTCATTGCAACTTCTGCCTCCCAGGTTCAAATGATTCTCCTGCCTCAGCCTCGTGAGTAGCCGGGACTACAGGTGCACGCCACTACACCCGGCTAATTTTTGTTTTTTGTTTGTTTATAAGATGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAATGGCTTGATCTCAGCTCACTGCAATCTCCACCTCCCGGGTTCAAGTGATACTCTTGCCTCAGCCTTCCAAGTATAGCTGGGATTATAGGCGTGTGCCACCACACCTGGCTAATTTTTGTCCAGCTAATTTTTGTGTGTGTGTGTTTTTTTCAGAGACGGGGTTTCACCATGTTGGCCAGGCTGATCTTGAACTCTTGACCTCAGGTGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAAGTGTGAGCCACTGCACCCAGCCTGGAATCTGCGTTTTTAACCAGCATCCCCAGAAATAACTATGCTCACCTGGTGATGGTCCCCAGCTGGATGTACATTTTATAGATGGAGACAATGAGGCCAGAGTGGGGAAGGGGTGCCTAGTGGGCAAAAGCTTTGGAGTCAGACTGTCTGGCTCTGCCTCTCGTGACCTTGGTGAAGTCACTGAACCTGCCTGAGCCTCAGTTTCTTCACTGTGTGCATGGAGAAGGCCACTAGCCGAGACTGCTGGCCTGATGACGTAAAAGGCTTGGTGCGAAGCAGGTGCTCACGGTGCACCCGCCCCTTTCTCCACCCCTGTCCCTTACTCCCTCTCCCCTTCGCTGATAGGCCTTTCTCTGTGCCCCACAG
Seq C2 exon
ACCAACAGAACTTCACAGTGACACTGGACCAGGTCCTGCTCCGCTGCCTGGAACACCAGCAGCACTGGAACCACCTGGACGAAGAGCAGGCCAGCCCGGACCTCTGGAGTGCCCCCAGCCCAGAGCCCGGTGGGTCCGCATCCCTGCTTCTGGCGCCCCACCCACCCCACACCTGCAGTGCCAGCTCCCTCGTCTTCAGCTGCATTTCACATGCCTTGCAATGGATCAGCCAAGGCCGAGACCCCATCTTCCAGCCACCTAGTCCCCCAAAGGGCCTCCTCACCCACCCTGTGGCTCACAGTGGGGCCAGCATACTCCGTGAGGCTGCTGCCATCCATGTGCTAGTCACTGGCAGCCTGCACCTGGTGGGTGGTGTCCTGAAGCTGCTGGAGCCCGCACTGTCCCAGTAGCCAAGGCCCGGGGTTGGAGGTGGGAGCTTCCCACACCTGCCTGCGTTCTCCCCATGAACTTACATACTAGGTGCCTTTTGTTTTTGGCTTTCCTGGTTCTGTCTAGACTGGCCTAGGGGCCAGGGCTTTGGGATGGGAGGCCGGGAGAGGATGTCTTTTTTAAGGCTCTGTGCCTTGGTCTCTCCTTCCTCTTGGCTGAGATAGCAGAGGGGCTCCCCGGGTCTCTCACTGTTGCAGTGGCCTGGCCGTTCAGCCTGTCTCCCCCAACACCCCGCCTGCCTCCTGGCTCAGGCCCAGCTTATTGTGTGCGCTGCCTGGCCAGGCCCTGGGTCTTGCCATGTGCTGGGTGGTAGATTTCCTCCTCCCAGTGCCTTCTGGGAAGGGAGAGGGCCTCTGCCTGGGACACTGCGGGACAGAGGGTGGCTGGAGTGAATTAAAGCCTTTGTTTTTTAAAGAAATGGCAAAGCCTTCGACTGACCCTTGACCCCCTGCTCCCTCAGCAGAGACGGAGGGAGGGGCTGCTGGTGGTCAGGGACCTGCACTGTGTAGAGGGAGCCTGGCTGTGTGGCCTGGAACAAGTCCCTCCCTCCCTGTGCGCCTCAGGTGGCCTGTCTGTGAGATGAGAAGAAGACCAGACTGAAGCCTGTTCACCATATGCCAGGCAGTGCTTTCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136877-FPGS:NM_001018078:14
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.130 A=NA C2=0.235
Domain overlap (PFAM):
C1:
PF0287516=Mur_ligase_C=PD(12.3=43.5)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)