HsaINT0067239 @ hg38
Intron Retention
Gene
ENSG00000136750 | GAD2
Description
glutamate decarboxylase 2 [Source:HGNC Symbol;Acc:HGNC:4093]
Coordinates
chr10:26216307-26217669:+
Coord C1 exon
chr10:26216307-26216885
Coord A exon
chr10:26216886-26217609
Coord C2 exon
chr10:26217610-26217669
Length
724 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGGA
5' ss Score
9.79
3' ss Seq
CTGCCTATTCTTCCTTGCAGCGC
3' ss Score
10.96
Exon sequences
Seq C1 exon
GCGGCCGCCCGCACTTCCCGCCTCTGGCTCGCCCGAGGACGCGCTGGCACGCCTCCCACCCCCTCACTCTGACTCCAGCTGGCGTGCATGGTCTGCCTCGCATCCTCACGACTCAGCTCCCTCCCTCTCTCGTGTTTTTTTCCTCCGCCGCCCCCTCATTCATCCCCACTGGGCTCCCTTTCCCTCAAATGCTCTGGGGCTCTCCGCGCTTTCCTGAGTCCGGGCTCCGAGGACCCTTAGGTAGTCCCGGTCTCTTTTAAAGCTCCCCGGCTTCCAAAGGGTTGCCACGTCCCTAAACCCTGTCTCCAGCTCGCATACACACACGCACAGACACGCACGTTTTCTGTTCCTGCGTGACACCCGCCCTCGCCGCTCGGCCCCGCCGGTCCCCGCGCGGTGCCCTCCTCCCGCCACACGGGCACGCACGCGCGCGCAGGGCCAAGCCCGAGGCAGCTCGCCCGCAGCTCGCACTCGCAGGCGACCTGCTCCAGTCTCCAAAGCCGATGGCATCTCCGGGCTCTGGCTTTTGGTCTTTCGGGTCGGAAGATGGCTCTGGGGATTCCGAGAATCCCGGCACAG
Seq A exon
GTAGGAAGGAGAACGGGGGCCTGCGGCGGGCGAGTTTTGCGGTGGTCTGGGGTTTGCGGAACTACGGAGAAGACGAAGGAGGTTTTTCCACCTGCAACAGGAAACTTCTTCGGGCGCTTCTCCCTGCTTTTGGGCTAAGTCCTTGACGGCCCAAGAGCTCAAGACCTCTACAGCCTCTTGTACCCTGGGAAGACGCCCAAATAGTCTCAGGCCCGTTCCACAGAAGGTTGGAAGAGCCCCCCAAAGACCGCGGTGTCTCGGGGACATGGAATTCCGTGGTCCTGGGGCGCTGCTAAGATCCGGGTGTCTGGACCCTGGGGTGGGACGGAGTGACCGTGAAGATAGAAAAAAAAAATGGGAAAGGTGAGAGATTTCTTTATCTAGAAAGACAGTCTGCGAAAAAATGGATAGCTTCAGTGTTTAGGAAAACTCGTCCAAGGTAGGCAGGGAGAGGAATTTGCCTGAGCCGATTGGCACCTGGAAGGGCAGCGGTGTGGGCTTCTCCTCGGGAAACAGATAAAGGAAATGAGGGCTGGCCCGGGCCGCCAGCCTCCCGCTTGCCTTCTGCACCTGCCGGCCTCACCGAGTCCTGAGCGGCCCCCAGGAGGAAGGCGGCCCCTCCTAGGACCCCGGACTGATTGATTTTCACATAGAACGAAATTTCACACGTCCGTCTGTTGTTCTCTTTCTGCCTCGCTGTCTGCCTGCCTATTCTTCCTTGCAG
Seq C2 exon
CGCGAGCCTGGTGCCAAGTGGCTCAGAAGTTCACGGGCGGCATCGGAAACAAACTGTGCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136750:ENST00000376261:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.458 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGTCCCTAAACCCTGTCTCCA
R:
GCACAGTTTGTTTCCGATGCC
Band lengths:
351-1075
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development