HsaINT0067250 @ hg38
Intron Retention
Gene
ENSG00000136750 | GAD2
Description
glutamate decarboxylase 2 [Source:HGNC Symbol;Acc:HGNC:4093]
Coordinates
chr10:26224539-26229777:+
Coord C1 exon
chr10:26224539-26224651
Coord A exon
chr10:26224652-26229661
Coord C2 exon
chr10:26229662-26229777
Length
5010 bp
Sequences
Splice sites
5' ss Seq
CCGGTACAT
5' ss Score
5.7
3' ss Seq
CGTGTTGCTGTGCACTTTAGGTG
3' ss Score
8.85
Exon sequences
Seq C1 exon
GTTCACCTATGAAATTGCTCCAGTATTTGTGCTTTTGGAATATGTCACACTAAAGAAAATGAGAGAAATCATTGGCTGGCCAGGGGGCTCTGGCGATGGGATATTTTCTCCCG
Seq A exon
GTACATGATATTTCAACTTTCTTTGTGTTTTTTCTTCTAATATGCAATGCCTTGTTGTAAACCTAGGGAAGATTAAAAATCTAGCCTATGCCTCTGCTTAGGTTAAATAGACTGTGTGTTGATCAAAAGAATGACTGTGATTAAGTGCACATGACCATTGAACATGCCTCCAAGCTAAGTAACCCATGCTTGAACATCAGTTATTTGTGTGCAAAGTGAGCATAATCAGAGATGGTACTTACCCAGTGCTTCTACTGTGACCCTACAAACAGGATGTACGGATAATGTGGAACAAAGGAATCAAGATTCCTAATCAGGAAATTCACTCTCTGATGCTCTTCCTAGAATTAGTGAAAGGAAATGGGTAGCCTCATTTAATAAAGCATTTGCTGTTCAAGGGTGCATAGCAAGGTATATCTACTCAGTAGAGCATATGGACCACTCTGTCTTTGAAATAACAAGCACCAAAGTGGATTTACACTAATTTCAAGGAGGACAGAGAACGCTTTGGGAGAGAATTTCTTAGAGCAAAAATAGAGGGTGACGATTTCTTCAAGAGATTTCTCATCCCTTCTCTTCTTTATCATGCCATTCAGTCTTTTCCATCCTGCCTTTTTATCACCAGCCATTGAATTCTAAGCTCCATTACTTAGACCTCTTCCAGCCAAGAGAATCAACCTGAAACAAAAAGCTGTGCCCTTGGTTTACAGTTCTGTGTGTGACCTTGGTTTGATGCAGAAAAGAAATAGAAGTTAGGAAGGCAATGCAAAGAGAGTCACTGACCCATGGAAAAGAAACCCGATGTGCAGACCATCAGCTAATCAGTGGCAGGAGCGGATGTCATTAGTCCACTGAGACAGGACCCACCTGAGAGAGAGGCCAGAGCAACACCTGTCGTTGTGTCAGACAGAGCAAAGGCCAAGTGGTTGTGCTCTCTCTTCAGCAAATCTACAAAGACAAGCAAATGATGAGGCGGGGATAGGGGAGAAAAGAAAAAGTGAAAAGAAGAAATGATAAGCAAGAGTGACCCCAAGGCCAGGGCTTAAGTTAAGCATGTTTGCCTGCAAGCTCTGGTCAGCTATTTTATGTGTTTAAATATATAGCACAATTTTTCAGGTGCTGAAGGAAAAGGTGTTAGTTAAATGGAAGGGAAAATTAGCCTTTTAAAAAGTCATTGAACACCAGCTGTGATGAATTTTAAGCTAGCCTTTATTTTTTATGGCACTTAGTACTTAGTTTTCCTTTGGAAAGCCATCCCTGTTGAGGGAGCTTGGTCATCATTGCCTGATGCTTTGAAAACATTGTTCATGAGGAATGAGGTGGGGTACAGAGATCCACATCATTTCTACCTTTCTTCTTCCCACCCTTGTGTGGTTGGTTATAGGATTGATCTGTCCCTGAGATGAATCAAGAACATGCTGGGCTCTATTTTTTTTTCTTTTATTTGCATTTATTTTATGCTGAATTTATTCCCGTGCATAAGTTTTAATGGTCCCCGGGAGTAGGGAGAGGACAGATGTACCTGTTGACCCTGAAAATTTGACTAATTTGACTAACAGCTAGGCCTAATTTACCTGGCTGGTCTGAAAAACCTACATGCCCCAGAAAACATACACCCAGAGAAATAATTCTCTTAGGCAGTTCTGCTAGGCTTAGAGCTTACCCTCCACCCTCACTGATAATGGGGGATTTTCACATGGAGAAGACTTCAGCTTGAGCATGGGAATTATAGGCTTCCTTGGAGCCTAAAGACCCATTTGCTCTTACGCCAAGATGCAAGCCATAGATGTCACACTACAGTGCAGTGCAGACATTGCAAAGTTGGGAGGAGACAGCAGAAAAGGTCATTGCAACCTGTTTCTGCTCTACTTTCTACAAGACATCACAGACGAGAAGTGGCTCATCACATCCTTACTGGCTATGGATGCTATTCCCGGGAGCAACCAGCCTTGCTCCTGCAGTAAAGGGTCTTACAATTTAAGGGGTGGGGATAGAGAAAGCCACACATCTTATGCATCTGGGATCTAAAAGTCTCATTCCCTGGGACTCAATGTGAAGAGTTAGGTCTGTGACTTAAAACATACTGTGTCATAGCTCCATCAATAATATCCAAAGCCTTCATGCTTCATGGAAAGTCCTTTAGGACTCCTAGAAGAAATCTGCTTTTGTGATGTCACCTACACTGGGAACCAGAGAAATACAGAGCATTCCTTACTGCTCAGCAGGTCACAAAGCACAAAGACTAAAGAGGGGCTAGGAAAGAAAGCTTGGCTTAGTCACCGACCTTTTCCTAGCTAACAGGGTTTTCATAATGTTTCAGCACTTGCTTTTATTCATGTATTTTATTTTTTATTTTTTTGAGACAGAGTCTCACTCTGTCGCCAAGGCTGGAGTGCAGTGGCACGATCTCAGCTCACTGCAACCTCCATCTCCTGGGTTCAGGCAATTCTTATGCCTTAGCCTCTAGAGTAGCTGGGATTACAGGCATGCACCACCATGCCCAGCCAATTTTTGTATGTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAATTCCTGACCTCAGGTGATCTGCCCACCTCAGTCTCCCAAAGTAGCACTTGCTTTTACATCCTTTCTTAGAGGATTCGTAGGAAATAAGAGCAGGTAGGGCTCACGCATTTGTCCTCATGCCTCTGTTACACAAAACAGTCTTCTCTGCCTGGAGGCCCAGAAGCCTCTTTCTCTCACTCAGAGCTGCTGAGCCTTTAGCCAGAGGACAGCTGAGTTGCAGAGTGAGGTGTGGGAGGGCAGGGCTGGAAGCTTCAGAAGAAATGCACATGAAGAGCACTTTCTTAGGATACGTCTTCCCCTTTCTCTTCTTCCCTCCTTCCTTCTCCAGCCTCTTTAAGAACAACTAAATTCTCAAACAAGATCATTTTGCTCCCCACAAGGGACATTTGGCAATATCTATAGATGCTTTTGATTGTCTGGGGGAGAGGGTGCTATGGGCATCTGGTGGGTAGAAACCAGGGATGCTGCTCAACACTTTACAATGCCCAGGTCAGCCCTCACCAGTTATGTTGCCCAAAATGTCAGGAAGTGCCAAAACCATGAGCTAGGATGGAATTTCCTTCTGAAGCAGACCCTGCTTCCAGCATCCTACAGCCAGCCTTTCACACCGGGTGTCTGCTCAGAGCAGGCGTGACCTGGATTCTACCTGATTCTACCTGTCCTGTATCTCTAGAGTCCAGAAAGGAAGGAATCGCCCTGATTTTGATTGAGGACAGAGGCATGTGTCTGGGTGATGAGTGCTCTGTGCTGGGCAGCCTGCTTGAATCAGAGCCCAGGGCTCAAGAGACAAAGGTCATACCCCTGCCTGGGCCATTCAGCTTGACATGGAGCCCTCCTGCTCCTCAGCCACCAGGAAGGAGAGTAACTCACAACACTCACGTGACGGCAGGACTTGGGGTGTTCCCCTTGGTCAGGAGGTAGAGGCAGTACCTTCACTCTGCCCCATGGCCTCATGTCTTCCATCCCAGCATATTAATTTGCATTCATAACAATCTGTCTTTCCTGAATTGCAAACATCCTAAACTTCCCAACAGCCCTGCATTTTCTTTGCTTGTCAAGTGAGACTCTACTTACAAGACACAAATCTTATGGCGTGGAATCCCTGACAACTTTTGGATGACACAGAAAACGTAACACAATATGGACTGAAAATTCTCTTAGTTGTATGTTTGTCTATACTTATGAAATAAGTTTTGTTAGCTAATACAATTCTATTATTTCAATGATGTCTTTGAGAGGGAAGAACTAGTTTAGAGGGAATGAATAGATGAGTATGATGAGATGGACGTGGAGGTTTATCCTTTATAACAGGGGTCCCCAACCCCCTGGTGGTGGATCGGTACAGGTCTGCGGTCTATTAGGAACGGGGCCACAGAGCAGTAGGTGAGCAAGGGGCAAGCGAGCATTACCGCCTTAGCTCTGCCTTCTGTCACATCAGCAGCCACATGAGATTCTCATAGGAGCGTGAACCCTATTGTGAACTGCGCATGCGAGGGATCTAGGTTGCATGCTCCTTACGAGAATCCAATTAATGCCTAATGATGTGAGGTGGAACAGTTTCATCCCAAAAGCATTCTCCACCCCACCCCCACCAGCCCCCGACCTTCCATATGTGGAAAAATTGTCTTCCACGAAACGCATCACTGCTGCCAAAAAGGTTGGAGACTGCTGCTCAGTAAAAATTGTTGATTAGGCCAGGCGTGGTGGCTCACACCTGTAATCCTAGCACTTTGGGAGGCCGAGGCGGGTGGATCATTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAATGTGGTGAAACCCCGTCTCTACTAAAAATACACAAAAAAATTAGCCGGGTGTGGTGGTGCATGCCTGTGGTCCCAGCTTCTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCAGGAGATAGAGGTGGCAGTGAGCGGAGATCGTGCCACTGCACTCCAGCCTGGGCGACAGAGTGAGACCCTGTCTCAAGAAAAAAAAAAAAAAGTTGATTAGCAGCTTACACCAGTAACAGCTGATTTATGTTAATCCAAATGCAAGGCACTGAATGAGTTGAAATGAAAAAAAAAAAGCTTTCTCCATCCAGATATAACCAGAATTTTACACACCTAGTGCAGAATGACCATGCTCACAAGCTGGGATGGAGGCAAACCTTTTGCTTTTGAATTAAAAACCTCTTCAAAGGGCTTCCAGCAAGAGTAGAATCCACTGCAGTTCCCCTTAGTGACTGAGATGGGGTGTGACAGTGGCACCTGTCCTGTCCCCATGTGCCCTCTGGGGTAGCGCCTTTGAGTCTGAGGATTCAGTTTAAAGATAGTCAATAGGTTTTTCTTCTGAGTCCAAGGAGGACTCAGGTCAGTGGAAATAAGGAATGTTGCTTGCATGTGAAATGAGGTTGATAATAAATAAAGTAACTGCGTGTTGCTGTGCACTTTAG
Seq C2 exon
GTGGCGCCATATCTAACATGTATGCCATGATGATCGCACGCTTTAAGATGTTCCCAGAAGTCAAGGAGAAAGGAATGGCTGCTCTTCCCAGGCTCATTGCCTTCACGTCTGAACAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136750:ENST00000376261:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.002 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0028214=Pyridoxal_deC=PD(36.8=95.1)
A:
NA
C2:
PF0028214=Pyridoxal_deC=FE(10.2=100)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development