HsaINT0068255 @ hg38
Intron Retention
Gene
ENSG00000115263 | GCG
Description
glucagon [Source:HGNC Symbol;Acc:HGNC:4191]
Coordinates
chr2:162145540-162147514:-
Coord C1 exon
chr2:162147353-162147514
Coord A exon
chr2:162145678-162147352
Coord C2 exon
chr2:162145540-162145677
Length
1675 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
3' ss Seq
AACTTTCACATTTCTTTCAGGAA
3' ss Score
9.45
Exon sequences
Seq C1 exon
ATCATTCTCAGCTTCCCAGGCAGACCCACTCAGTGATCCTGATCAGATGAACGAGGACAAGCGCCATTCACAGGGCACATTCACCAGTGACTACAGCAAGTATCTGGACTCCAGGCGTGCCCAAGATTTTGTGCAGTGGTTGATGAATACCAAGAGGAACAG
Seq A exon
GTAAGAGTCTAAGCCTGGCTCAAAACTTGCTTATAAATGTATTAAATAGGTCTAAAATTTCTCTTGACATTATTAAGTTCTTATGCTCGTCAAATAGTGCCCATAAGCCCTGATCATTTTGAAGATGTTTAGGGTTGGGGATGCTCTCCTTAGTATTATGCCCCCGAATGTCTTAACCCGCACCCCTCTAAACCACTTACCCAACCTCCAGTGTGACATAGCCTTTAAATTATTTTCCCAGTGGTAGTCCTAGCAATATTTACTTGCTTACTCATTTTCCCTTAAAGTGAAAGTTTACTTTTGTGGACCTACGAGGTTACCAATCTAATTTCTACCAAAAGATAGAGCAAATATAACATTCTTTCGTGGGGTTCAAACCCAACATTAAAATTATCCCCCAGCCAAGGGTAAGGAATGGAAACAGATGCATTCCTTTTCTTGTAGAATAAAATCCAAGACATGCATTTAAAATTACAGCCTAGCTGCACAGCATAGAGAGAGAAGGCAGCAAATAAGAACACAAGCCTATCGTAAGGCATACATTTTAATGTTGGATTTTCTTTGACGAGTGTTGGGTTTTTTGCTGCATCTAGGCTACTGGAGGAAATTATCCGCAAGGGTTTCACAGAGATGGTGGAATTTCACAATTTTTTTGGAGGGTGGCCCACAAGAGGAAGGGAGTTATGCATAGAAAGTAGCTGAAGAAATCAAAAAATCAGGAAAAGGACATAGATTTGTCTGGATAGACTGGAGAAGAGAGAGAGTGAGAGTAAGAAAGGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAACAAGCAAGCAGGAGGAATAGGAGAAACAGAGTTGCTAATCAAAGGTTCTTAAAGTAGAGGGTACAGCCACAGGAAGATGGCTATCATGGTCAGAGCAGACACTGGGAGAGGTCCCTCTTAAGGACTACAGTGAAAGGTGAGAAATCACAAATTTATAAAAATGCAAACAACTGTCCTCATTTTCTAGAATGGGAATGCCACAACTTGGTAAATGGATGTAAAGCAATCCTCACACTCAAGCAGTGTTGCCTATGTGTTTAAAATGAGGTGATATGGGGTAATATGTGCCAGGGAGACTGACAGCAGCTGATGGCTCACCTCCACGGTGCTCTGCACACACTTGATGTTGATATGGGGTCATCTTCTTTGCTTTCCTTGTTACTAGCAGATCACACATTTTCTTTAATCCATTATCAAGTGGTCCTTTTGGTAACAATTCAAGATGGTCCTTTGCTTTCCCTCAAATCAATTAACTAACTCTGACCCCATACTTACTAATAACAAACAGCTGCCTTGCTTGCAAGTCACATAGTGCAGTGGATAGCCTGTATCCATTGAGACTGAAGTCAAAGGTAAGGCAGCTTTAATAACCAATGACATACATAAGCAGGGGATTGCAGATGGGTATGCTGGGAAGGGAGGGGGAGCTTTAGCCCACCGATTGTTATTAGCTCTCTTCCACCAGTTTCAATCCAGAACATTAATGTAGCTTCACGACAAATCCCCTAGCAACCCTCATCTCCTAAACTCCCTAAGCCCCTTCTACATAGAATCCTGAACCCAAAGTTGCCACTGCTTATAGGTGAGAACCATATTGCCAAAGAGACAGATCTTCAATTTAACTTTCACATTTCTTTCAG
Seq C2 exon
GAATAACATTGCCAAACGTCACGATGAATTTGAGAGACATGCTGAAGGGACCTTTACCAGTGATGTAAGTTCTTATTTGGAAGGCCAAGCTGCCAAGGAATTCATTGCTTGGCTGGTGAAAGGCCGAGGAAGGCGAGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115263:ENST00000418842:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.455 A=NA C2=0.213
Domain overlap (PFAM):
C1:
PF0012315=Hormone_2=WD(100=50.9)
A:
NA
C2:
PF0012315=Hormone_2=WD(100=59.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CATTCTCAGCTTCCCAGGCAG
R:
GCCTTCCTCGGCCTTTCAC
Band lengths:
294-1969
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development