HsaINT0076407 @ hg19
Intron Retention
Gene
ENSG00000156510 | HKDC1
Description
hexokinase domain containing 1 [Source:HGNC Symbol;Acc:23302]
Coordinates
chr10:71008180-71010191:+
Coord C1 exon
chr10:71008180-71008484
Coord A exon
chr10:71008485-71010045
Coord C2 exon
chr10:71010046-71010191
Length
1561 bp
Sequences
Splice sites
5' ss Seq
CAGGTGGGC
5' ss Score
8.07
3' ss Seq
TGCTGCTTTCTCCATCACAGAGA
3' ss Score
8.42
Exon sequences
Seq C1 exon
GTACCCAAAACGCCTGCACAAGGTGGTGAGGAAACTGGTCCCAAGCTGTGATGTCCGCTTCCTCCTGTCAGAGAGTGGCAGCACCAAGGGGGCCGCCATGGTGACCGCGGTGGCCTCCCGCGTGCAGGCCCAGCGGAAGCAGATCGACAGGGTGCTGGCTTTGTTCCAGCTGACCCGAGAGCAGCTCGTGGACGTGCAGGCCAAGATGCGGGCTGAGCTGGAGTATGGGCTGAAGAAGAAGAGCCACGGGCTGGCCACGGTCAGGATGCTGCCCACCTACGTCTGCGGGCTGCCGGACGGCACAG
Seq A exon
GTGGGCCAGCACAGCCTCCCTCTCTGAACAGCCATCCAGGGCTCCCGTCAAAACTCCTTAAAGCCAGTGAGGTTCTTGGTTTTTAGAAACTTGGGTTCACGTCTCTAATGGAGGGCAAGAGTAAGAAGAAGGCTAGTATTCTTTCTAAATCTGTTGGCCTTTGTTAACCCAAGGCATTTGCAGTAAAAACAAAACAAATAAACAAACAAAAACACAAAAAGCCTACATTAGGTTATGTGTGTGCACTTATGTGTGTGTAGATGAGAACATGAGTGTACCCCCCCCGACCCCCAGATCCTGACCCCAGGAACTTTGTTTTAGATGCCTGAGATTGCCTGGGCTTGTCTTCCTGCTGCTTCTCTGGCTCTGTTCTCTTCTGCAGCTTGGCTCACTTCCCTTTCCCTCTCATTGCTTCTGCCCCCAACTTCTCCAACCCTTGATCCTTCTGGTCCTCGGTGCTCAGCCAAAAGAAGCCACTAAGTAGTGAAATCAGTTCTTCAGACAAATTATTTTACCTCTTTGAATCTCACGAGACTCTTCCGGAAATAATGACCTTAGTAAAATGCTTTACATCTTATAATTTGCTTTTGAACCTTTCATTTCATTTCATCCTCACAACCACTTGGAACGTTACCAAAGAGGAAATGGTTCCCATTTTATGGATGCCATACCTGAGACTTACAGAGGCTAGATGACCTACTCAAGGTCCAACAGCTGTACTTGGGATCTCTTAACTGAGAGCAGTAAAAGACACTGTTTATTTTATTTTTATTTTTATTTTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTAGCGTGATCTCCGCTCACTGCAAGCTCCGCCTCCCAGGTTCACACCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCAGCACCACACCCGGATAATTAATTTTTTGTATTTTTAGTAGAGATGGGGTTTCACTGTGTTAGCCAGGATGGTGTCGATCTCCTGACTTCGTGATCCACCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCAGACCGGAGGCCCCTTGAGTATAAGAATCATGCATTTCCTTGACTGGATGCCCTGTACCGTTCCTTGGGGCTCCCGAGAAGGCTGTCAGTCAGTGAAGCTGAAAGAGCCTTCAGAGGTTCAGTCTCCTGATTTTGCAGATGTGGAAGGATGGGACCTTGCCTCTCTTGCTCAAGATAAAAAGCCATTTCTCAGAAGCCCCAGGTCCCTTGACTCCAGGCCAGGGCTCTTTTCACGGCACCTCACTGGCGATAGTGTAGGTGGTGCCTGGGACTTTACCACAGAAGTGGAGGCCAAGGAAAGCAGCCTGGCCTCACGCAGGCTCAAGATGCCTGCCCGGGGCCCGGGCACTGTGCAGGGTGGCCCCCACGACCCTCTGGTCTATGAGGCCCAGGAGTGCAGGCCCTGGGTCCGCTCTGCTCCGACGTCTCCTCTTCCTCCCAATGCCCCGACACAAGTCCCTGTCATGGAATGCAGCTGCTGCTTTCTCCATCACAG
Seq C2 exon
AGAAAGGAAAGTTTCTCGCCCTGGATCTTGGGGGAACCAACTTCCGGGTCCTCCTGGTGAAGATCAGAAGTGGACGGAGGTCAGTGCGAATGTACAACAAGATCTTCGCCATCCCCCTGGAGATCATGCAGGGCACTGGTGAGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000156510-HKDC1:NM_025130:10
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0372711=Hexokinase_2=PD(16.7=38.8),PF0034916=Hexokinase_1=PU(29.3=58.3)
A:
NA
C2:
PF0034916=Hexokinase_1=FE(23.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCACAAGGTGGTGAGGAAAC
R:
TGATCTTCACCAGGAGGACCC
Band lengths:
357-1918
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)