HsaINT0076410 @ hg38
Intron Retention
Gene
ENSG00000156510 | HKDC1
Description
hexokinase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23302]
Coordinates
chr10:69257036-69257426:+
Coord C1 exon
chr10:69257036-69257131
Coord A exon
chr10:69257132-69257326
Coord C2 exon
chr10:69257327-69257426
Length
195 bp
Sequences
Splice sites
5' ss Seq
AACGTAGGA
5' ss Score
3.85
3' ss Seq
GTTTTTGTTTTTGTTTTTAGGAG
3' ss Score
10.78
Exon sequences
Seq C1 exon
GGAACACTCATAGGGTGGACCAAAGGTTTCAAGGCCACTGACTGTGAAGGGGAGGACGTGGTGGACATGCTCAGGGAAGCCATCAAGAGGAGAAAC
Seq A exon
GTAGGATGTGGTGTTGAGGCTCATGCCTGCTCTTGCTGCCTTCCCCAGGCCCCTCTGCTCTGCCATCCTCTGCCCAGTTCCTATGACTCTGGCCTCTGTCTGCCTTGGGATAACATGCCCCTCCTAAACCTGTTTGGCTTGCACATTCAACTCATAGTAAAGCTGGGTTTTTTTTGTTTTTGTTTTTGTTTTTAG
Seq C2 exon
GAGTTTGACCTGGACATTGTTGCAGTCGTGAATGATACAGTGGGGACCATGATGACCTGTGGCTATGAAGATCCTAATTGTGAGATTGGCCTGATTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000156510:ENST00000354624:13
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.009 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0034916=Hexokinase_1=FE(15.1=100)
A:
NA
C2:
PF0034916=Hexokinase_1=PD(11.2=67.6),PF0372711=Hexokinase_2=PU(10.7=23.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGAACACTCATAGGGTGGACC
R:
TGCAATCAGGCCAATCTCACA
Band lengths:
195-390
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development