HsaINT0076956 @ hg19
Intron Retention
Gene
ENSG00000122566 | HNRNPA2B1
Description
heterogeneous nuclear ribonucleoprotein A2/B1 [Source:HGNC Symbol;Acc:5033]
Coordinates
chr7:26237242-26240413:-
Coord C1 exon
chr7:26240192-26240413
Coord A exon
chr7:26237353-26240191
Coord C2 exon
chr7:26237242-26237352
Length
2839 bp
Sequences
Splice sites
5' ss Seq
GAGGTAACG
5' ss Score
9.65
3' ss Seq
AATGGTATTTTCCTTTGCAGAGA
3' ss Score
9.82
Exon sequences
Seq C1 exon
AGTGGGGGGGAAGGTTCTAGAAAAGCGGCGGCAGCGGCTCTAGCGGCAGTAGCAGCAGCGCCGGGTCCCGTGCGGAGGTGCTCCTCGCAGAGTTGTTTCTCGAGCAGCGGCAGTTCTCACTACAGCGCCAGGACGAGTCCGGTTCGTGTTCGTCCGCGGAGATCTCTCTCATCTCGCTCGGCTGCGGGAAATCGGGCTGAAGCGACTGAGTCCGCGATGGAG
Seq A exon
GTAACGGGTTTGAAATCAATGAGTTATTGAAAAGGGCATGGCGAGGCCGTTGGCGCCTCAGTGGAAGTCGGCCAGCCGCCTCCGTGGGAGAGAGGCAGGAAATCGGACCAATTCAGTAGCAGTGGGGCTTAAGGTTTATGAACGGGGTCTTGAGCGGAGGCCTGAGCGTACAAACAGCTTCCCCACCCTCAGCCTCCCGGCGCCATTTCCCTTCACTGGGGGTGGGGGATGGGGAGCTTTCACATGGCGGACGCTGCCCCGCTGGGGTGAAAGTGGGGCGCGGAGGCGGGAATTCTTATTCCCTTTCTAAAGCACGCTGCTTCGGGGGCCACGGCGTCTCCTCGGCGAGCGTTTCGGCGGGCAGCAGGTCCTCGTGAGCGAGGCTGCGGAGCTTCCCCTCCCCCTCTCTCCCGGGAACCGGATTTGGCGGCCGCCATTTTCATGGCTCGCCTTCCTCTCAGCGTTTTCCTTATAACTCTTTTATTTTCTTAGTGTGCTTTCTCTATCAAGAAGTAGAAGTGGTTAACTATTTTTTTTTCTTCTCGGGCTGTTTTCATATCGTTTCGAGGTGGATTTGGAGTGTTTTGTGAGCTTGGATCTTTAGAGTCCTGCGCACCTCATTAAAGGCGCTCAGCCTTCCCCTCGATGAAATGGCGCCATTGCGTTCGGAAGCCACACCGAAGAGCGGGGAGGGGGGGTGCTCCGGGTTTGCGGGCCCGGTTTCAGAGAAGATATCACCACCCAGGGCGTCGGGCCGGGTTCAATGCGAGCCGTAGGACAAAGAAACCATTTTATGTTTTTCCTGTCTTTTTTTTCCTTTGAGTAACGGTTTTATCTGGGTCTGCAGTCAGTAAAACGACAGATGAACCGCGGCAAAATAAACATAAATTGGAAGCCATCGGCCACGAGGGGCAGGGACGAAGGTGGTTTTCTGGGCGGGGGAGGGATATTCGCGTCAGAATCCTTTACTGTTCTTAAGGATTCCGTTTAAGTTGTAGAGCTGACTCATTTTAAGTAATGTTGTTACTGAGAAGTTTAACCCTTACGGGACAGATCCATGGACCTTTATAGATGATTACGAGGAAAGTGAAATAACGATTTTGTCCTTAGTTATACTTCGATTAAAACATGGCTTCAGAGGCTCCTTCCTGTAATGCGTATGGATTGATGTGCAAAACTGTTTTGGGCCTGGGCCGCTCTGTATTTGAACTTTGTTACTTTTCTCATTTTGTTTGCAATCTTGGTTGAACATTACATTGATAAGCATAAGGTCTCAAGCGAAGGGGGTCTACCTGGTTATTTTCTTTGACCCTAAGCACGTTTATAAAATAACATTGTTTAAAATCGATAGTGGACATCGGGTAAGTTTGGATAAATTGTGAGGTAAGTAATGAGTTTTTGCTTTTTGTTAGTGATTTGTAAAACTTGTTATAAATGTACATTATCCGTAATTTCAGTTTAGAGATAACCTATGTGCTGACGACAATTAAGAATAAAAACTAGCTGAAAAAATGAAAATAACTATCGTGACAAGTAACCATTTCAAAAGACTGCTTTGTGTCTCATAGGAGCTAGTTTGATCATTTCAGTTAATTTTTTCTTTAATTTTTACGAGTCATGAAAACTACAGGAAAAAAATCTGAACTGGGTTTTACCACTACTTTTTAGGAGTTGGGAGCATGCGAATGGAGGGAGAGCTCCGTAGAACTGGGATGAGAGCAGCAATTAATGCTGCTTGCTAGGAACAAAAAATAATTGATTGAAAATTACGTGTGACTTTTTAGTTTGCATTATGCGTTTGTAGCAGTTGGTCCTGGATATCACTTTCTCTCGTTTGAGGTTTTTTAACCTAGTTAACTTTTAAGACAGGTTTCCTTAACATTCATAAGTGCCCAGAATACAGCTGTGTAGTACAGCATATAAAGATTTCAGCTCTGAGGTTTTTCCTATTGACTTGGAAAATTGTTTTGTGCCTGTCGCTTGCCACATGGCCAATCAAGTAAGCTTCAGCTTTCAGTAATTGTTATCTTAGAGATTATGCCACGTGAATGTATTTTATTGTACATATGGTTAAGCTGAGTAATTCATATTCTGTATTGTCATATATCAAATATAGACATGTCCACCAAAAATTAAACTTTTTAAGCTTCGAGTGCTGCTGGTCATAAAAATTAATTTGTCCTGGTTATAAGAGTAATTTTTAAGGTTATTTCTAATGCATATCTTTAAATATTTTCGTAACTGAGAGTCATATGGAGAAACTTAGTGTTTGTTGTAAAAAGTTGTGTTTTTTTGGCTGAGATACTTAGAATCACCACCAGAGGGGGCAGTTAAGGGAAAATAAATGATACTTTTCAGATATTGAATAGTGAAATAAAAACTTTGGGTCATAAGTAATGAACCAAGAGTTATTTTCTGATGTTTAAAAATAGAAATTTGCGTTTTTAGGTTGTAGGGTTGAAATTTTTGGTAAAGATTCTTTAATAATCCTTTGATAATCACGGTCTACATTTGTTTATTTTTCCTTAGAAAGTTTTTTTTTTAATTAATAATTTAAGATAATTTAATGTTGAGTAAATTTATATCAAGCATTAATGACTTTGAAACTTGTGTAGATCAGCTGAGGCAATTTTTTGGTGTAACACAACTAATATGCAGTTTAACATATGGTTTAAATTTGATGTAAGTTTTTTTTTTCCCCCCAGAAAACTTTAGAAACTGTTCCTTTGGAGAGGAAAAAGGTACTCTGCCAGCAGGTCACCTCATATTTAAGAATTTAATTTCCTGCATACAAAGAGGAAAATGTAAATAAAAATTGAAATGGTATTTTCCTTTGCAG
Seq C2 exon
AGAGAAAAGGAACAGTTCCGTAAGCTCTTTATTGGTGGCTTAAGCTTTGAAACCACAGAAGAAAGTTTGAGGAACTACTACGAACAATGGGGAAAGCTTACAGACTGTGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000122566-HNRNPA2B1:NM_002137:1
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.417 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF142591=RRM_6=PU(40.0=75.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)