HsaINT0078782 @ hg38
Intron Retention
Gene
ENSG00000182054 | IDH2
Description
isocitrate dehydrogenase (NADP(+)) 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:5383]
Coordinates
chr15:90085001-90085387:-
Coord C1 exon
chr15:90085275-90085387
Coord A exon
chr15:90085099-90085274
Coord C2 exon
chr15:90085001-90085098
Length
176 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGT
5' ss Score
10.47
3' ss Seq
CCTGCAACCCCCGTCCCCAGGGC
3' ss Score
8.35
Exon sequences
Seq C1 exon
GCTTTGGCTCCCTTGGCCTGATGACGTCCGTCCTGGTCTGCCCTGATGGGAAGACGATTGAGGCTGAGGCCGCTCATGGGACCGTCACCCGCCACTATCGGGAGCACCAGAAG
Seq A exon
GTGAGTGCAGGGCATGGGGCCTCACAATGCCCCTCTACCCCAGGGGCCTAAAGCCCACTGGGCTGAGGGCTGGAAGGACGAGCCTGACCCACCAGCCCAGGGGCGGGCAGCTGTATCTGGGCAGCCTCCTCACTAGCTGGCTCGGCTCTTGATCTCCCTGCAACCCCCGTCCCCAG
Seq C2 exon
GGCCGGCCCACCAGCACCAACCCCATCGCCAGCATCTTTGCCTGGACACGTGGCCTGGAGCACCGGGGGAAGCTGGATGGGAACCAAGACCTCATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000182054:ENST00000330062:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.237 A=NA C2=0.061
Domain overlap (PFAM):
C1:
PF0018015=Iso_dh=FE(17.8=100)
A:
NA
C2:
PF0018015=Iso_dh=FE(15.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTTGGCTCCCTTGGCCTGAT
R:
CTGATGAGGTCTTGGTTCCCA
Band lengths:
210-386
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development