HsaINT0088126 @ hg19
Intron Retention
Gene
ENSG00000170759 | KIF5B
Description
kinesin family member 5B [Source:HGNC Symbol;Acc:6324]
Coordinates
chr10:32308786-32310059:-
Coord C1 exon
chr10:32309950-32310059
Coord A exon
chr10:32308888-32309949
Coord C2 exon
chr10:32308786-32308887
Length
1062 bp
Sequences
Splice sites
5' ss Seq
AGAGTAAGT
5' ss Score
9.35
3' ss Seq
TTATTTTTTTCTTTCGTCAGCCA
3' ss Score
5.55
Exon sequences
Seq C1 exon
CAAGCTGTTGAACAGCAGATCCAGAGCCATAGAGAAACTCATCAAAAACAGATCAGTAGTTTGAGAGATGAAGTAGAAGCAAAAGCAAAACTTATTACTGATCTTCAAGA
Seq A exon
GTAAGTATTATACTTCTCTAGTTAGGAGGAAAGAATCGGTTACTGATGGTCATGGTATATATTCTTATTAGAAACCTGCAGTTTTCATCAAAATTACATTTTTATCTTGGAAAATAAAGAATTTTCTCATTTATGAGTAAAACTTCTAAATTCCAGGTGAAATTTTTGAGGCTTTTTTTTAGGTCTTTTGATCTAAATTATTCAGTAAAAGAAAAAAATCCCCAACCTAAGTCTATTATTGCATACCACAGTCTTCTCCAAATCCTTTATTTAGTTTCCTTTTTTAAAAAAATTCTTGGCTGGGTGCAGTGGCTGATGGCCTGTGACCCCAGTGCTTTGGGAGGCTGGGGTGGGAGGATCACTAGAAGTCAGGAGTTCAAGACCAGCTGGGCAACATAGTGAGACTCCATCTCTACAAAAAATAATTTTTTAAATTAGCTGAGCTTGGTGGCACATGCCTGTAGTCCCAGTGACCCAGGAGGCTGTGGCACGAGGATTGCTTGAGTATTGGAATCTGAGGCTGAAGTGAGCTATGATTGTACTACAGCCTGGGTGACAGAGCGAGACCCTGACTCAAAATTCTTAACTGGGAAAAACTTTTCTGGAAATTCTATGGATTTTCAAAGGTTTTTTTTTTTTTAAGTTGTCATCTTAGTTTATCTAGAAGCAATTTCCCTGCCTCCATAACCATGTGCACATACATAGAGTTTATGGAAGTCAGAGTTTGCAACAATTTGAGTAGGAACCAAGAAGAGAATAACATAACAAAATAATGATGAGGTTTGGGGCGTAGGTCTTACTATGAATACCTGATGGAAGTAGGCATAAGGATTCAGGAAGATGAAAGACAGAGGAGAACAGAATCATGATTTCAAACCAAAATACGAAAAATTTTGTATGTCCACAAGTAGCCAGGTCCCTTTCCTCTTTTCCTCCATAGGGTATAGGATAACAGAAAAGTCCTTGATGAGATTATAGAATTTAAAAGTTTGGAAATTTTAATGATGACATTGAGAAAACTGTGATATTGATACTGTGTTAATTATTTTTTTCTTTCGTCAG
Seq C2 exon
CCAAAACCAGAAAATGATGTTAGAGCAGGAACGTCTAAGAGTAGAACATGAGAAGTTGAAAGCCACAGATCAGGAAAAGAGCAGAAAACTACATGAACTTAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000170759-KIF5B:NM_004521:19
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.730 A=NA C2=0.943
Domain overlap (PFAM):
C1:
PF045827=Reo_sigmaC=FE(22.9=100)
A:
NA
C2:
PF045827=Reo_sigmaC=PD(10.2=45.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTTGAACAGCAGATCCAGAGC
R:
GTAAGTTCATGTAGTTTTCTGCTCT
Band lengths:
207-1269
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)