HsaINT0088902 @ hg38
Intron Retention
Gene
ENSG00000164344 | KLKB1
Description
kallikrein B1 [Source:HGNC Symbol;Acc:HGNC:6371]
Coordinates
chr4:186255992-186257365:+
Coord C1 exon
chr4:186255992-186256087
Coord A exon
chr4:186256088-186257225
Coord C2 exon
chr4:186257226-186257365
Length
1138 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGC
5' ss Score
10.22
3' ss Seq
TATATATTGGTTACTCACAGGTG
3' ss Score
7.14
Exon sequences
Seq C1 exon
AATTCCAAAAACCAATATGCCTACCTTCCAAAGGTGACACAAGCACAATTTATACCAACTGTTGGGTAACCGGATGGGGCTTCTCGAAGGAGAAAG
Seq A exon
GTAAGCATGACGCTTTAAATATTGCTTCTAGAGTAAGTCTCACATGTTGAAATACATGGAGTGGGTCGTTTTAATCGGTTTCTGTCTGAAATTATATCTAAACTCTTTATCTTTCCTATCTATTTATTCCCAAATATTTATTCAGTTATTCTTAAAAAATGTATTTTTGCTTTGGCTTGAAAAAAAATTTTAGGGAGACTTTTAAGCATCTTACTTCATTATAAAGATCAGTTGCTTGACTTTGCATGAAGCAGATTGGGCCCTTCTAGGGCTGACAAGCCCGTGCAAGACCACCCGCTCCTCAGTGTTAGTAGCGTTCCCGTCTCCCAAAACCATGTTCTCCCTTGATGCTAATGGCCGGGAGCACAGGCAGGTGTGTCGTCTCACTATGGAGAATAATATTTGTGTCATTCTTTACAGAAGAAGGTAGCTTGCCAAACTGTCTCCATCTTTCCCGATTCAGTCTTTTGTTCAAGTAATTCACATTTTTAGATTTTTTATTGGTAATCTGAGACAAGAAGAAATTTAAAGTAATCTTCACTAAGCCATGAAAGCTCCCAACATTGTTCTCCATGAGAGATGCTGGCCTGCATTTATTCAAAAACAAAAGACCCCTCTGTTGCCAAAGCTCGGAGGGCTTTTCAGAAACGATATAGTTGTAAATTATAATTTTGAATATATAAAGCAAAAAAATGAAAAGTGAGAACTTCCAGGCTTTGGATTGTTGTAGGTGATAAATATAAAATGGGATTTCTGGGGGGCTGCTACTGAGATGAGGGGATGGCAGAAAACATGGAAGCAAGGTCTCTGGTCAGCCCAGGGTGCTGGGCTTGTCCCAACACCACGTAGGCAATAAGAGGACAGTACAGGGTGCCGTCTCTCTCCCTCTTCCTCTCTCTGTCTCTCTCTCTCTGTGTGTGTGTGTGTGTGTGTGTGTAACACTACCTTCCCAATTTTTACTGTCTATTTGTATTCAAAGATAAGGTCCTTATGAAAAATACACTGCTCTGATTCACTTTAAAACTTATTTCCATATTTATTATTTATTGTGGGAATAATAATATTCCCAATATTATTATTTATTATTTAAGTTATTATTATTAACTTCCCTCTGAGGTTATATATTGGTTACTCACAG
Seq C2 exon
GTGAAATCCAAAATATTCTACAAAAGGTAAATATTCCTTTGGTAACAAATGAAGAATGCCAGAAAAGATATCAAGATTATAAAATAACCCAACGGATGGTCTGTGCTGGCTATAAAGAAGGGGGAAAAGATGCTTGTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000164344:ENST00000264690:13
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(13.9=100)
A:
NA
C2:
PF0008921=Trypsin=FE(19.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCAAAAACCAATATGCCTACCT
R:
ACAAGCATCTTTTCCCCCTTCT
Band lengths:
230-1368
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development