HsaINT0088910 @ hg38
Intron Retention
Gene
ENSG00000164344 | KLKB1
Description
kallikrein B1 [Source:HGNC Symbol;Acc:HGNC:6371]
Coordinates
chr4:186251219-186251649:+
Coord C1 exon
chr4:186251219-186251328
Coord A exon
chr4:186251329-186251486
Coord C2 exon
chr4:186251487-186251649
Length
158 bp
Sequences
Splice sites
5' ss Seq
CTGGTAATG
5' ss Score
5.67
3' ss Seq
TGTGTTTATAATTGACACAGAAC
3' ss Score
4.38
Exon sequences
Seq C1 exon
AAATGTTTGTCTTCTTAAAACATCTGAAAGTGGCACACCAAGTTCCTCTACTCCTCAAGAAAACACCATATCTGGATATAGCCTTTTAACCTGCAAAAGAACTTTACCTG
Seq A exon
GTAATGTGATTTGATAATAATATTACATAAAATGTAACCTATTTCATGACTTTTAACAGCAACAGTGATGAAACAATCCTCAAGGTAACAGAAACTTGTGTAAATGTCGTTCATTGCTTTTCCCATCTGATATCTTTTTGTGTTTATAATTGACACAG
Seq C2 exon
AACCCTGCCATTCTAAAATTTACCCGGGAGTTGACTTTGGAGGAGAAGAATTGAATGTGACTTTTGTTAAAGGAGTGAATGTTTGCCAAGAGACTTGCACAAAGATGATTCGCTGTCAGTTTTTCACTTATTCTTTACTCCCAGAAGACTGTAAGGAAGAGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000164344:ENST00000264690:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.132 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0002421=PAN_1=PD(36.9=81.6)
A:
NA
C2:
PF0002421=PAN_1=PU(61.9=94.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGCACACCAAGTTCCTCTAC
R:
TCTCTTCCTTACAGTCTTCTGGGA
Band lengths:
242-400
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development