HsaINT0088949 @ hg19
Intron Retention
Gene
ENSG00000111796 | KLRB1
Description
killer cell lectin-like receptor subfamily B, member 1 [Source:HGNC Symbol;Acc:6373]
Coordinates
chr12:9747870-9750757:-
Coord C1 exon
chr12:9750642-9750757
Coord A exon
chr12:9748018-9750641
Coord C2 exon
chr12:9747870-9748017
Length
2624 bp
Sequences
Splice sites
5' ss Seq
TGAGTGAGT
5' ss Score
6.51
3' ss Seq
ACTTTTCTTTTGCTCCACAGCTT
3' ss Score
10.1
Exon sequences
Seq C1 exon
ATACACACACAGAACCTGATACGTGACAAAGCAATTCTGTTTTGGATTGGATTAAATTTTTCATTATCAGAAAAGAACTGGAAGTGGATAAACGGCTCTTTTTTAAATTCTAATGA
Seq A exon
GTGAGTATTAGATGAGCTAACTTTAATATTCAATTTATATCAGGTTTACACTGCAAGGTAGTAACACTGAAGATTGAGTTTTGTAGTTTTAATTTGGTTTAAAAACTCAAGAAGTTCTGAATAGGCTAAGAACATGGATGATTTCAAAGTTGGTTGGAAAGTTCTATATATGAAAAGATATCAGCTCTTTATGAGAAAATATATTTTTATCTGCAATGGAGTTTTAGGGGACAGGAAATAGACTAACTTATTTGAAACGGGCACATTAAATTAAAAATAGTGATTATCTGGAGACCACTGGCACACAGAATGTCTTACGTTGTATTTTTCAAACTGTGGGAAAATATACATTAGTAGGTAAAGAGACCAATTTAGTGGGTCACAGCTGGCATTAAAAGAAAAGAAAAAATAGTAAATATCAGAGTGTGGAACCCAGACACCCACGTTGTGACAAAAATTGCAGTATATTTGAACCACTGGTGTGAAAGACAGAGGTACTTGAGACGATGTGATGAAAACATGTCTAACCCACAAAAGAGCTATTTGCTGTTTTCTCTTCAGTGTGACATGCTTTTGTCTTGTGTAAGATGGTCAAAATTACCATCAACGTACTATGAGGCATTTGCGACACAGGCAAATTTCATGTTTTAGCAGAATTCATGGATAATTTTGCAGAAAAAGGCAGGGTGTTTTCTTCCCTCACAAGCGAAAATGTATAGGCCTTCAACCACATTTCTGTAAAGAACTTTTAATGAGTTTTTCAAAAGAGATAATATAAACAGTTATATTTAATGAGTCTGTAAATGATTTAGTCAAATTGGCAGAATTTACATTTAAAATGTATTTTCCGTCACTCAAAAAACAAGAGGTTAAAATCTAAAACATAGGAGAATGTTTTAAGTTTGTCTACATTATCCTAAGATAATTTATTAAGTATGGAAAGTATTAAACACTGAAAGAAATGTTGGCTCAATCAGCAAAGTTTTGACATTATATGAGCCACATTCTAAAATATTTTATAAAGTGTAAGATTTTAAAATAAAGATGATTTAAAATAAGTGTTCTGGACTAGAATAAATTTATGAAAAGCCAAACATACACATTATGTTTAAAAACATCTCTCTTGATTTTTATATTGCTTTCTGGGGGTTATTTTCAATATTTTATTTACAAATAAATGAAAGTAGGTTTGCTATTAATTTATTTTTATCTTTCCACACATGGTATTGGTGAATTAGCATTTATTAAGTATAGTTTGTGTGTGTGTTTCTTAATGGGGTCATAATGCAAAATGTTTATTTTATTGTGGTTCACAGTAAAAAATAAAATTTGAAAACATTGAAATGTGAACATAAATATGTGTAAAGTGGATGGAGGAAATTCAGTTGAACTTTTCATTTTATTCTGAGGAGAAAGATGATGCTTTAAGATAATAGTGATCAGGTAAACCTGGAAGGTATCACGTTATAGTAGAAAAAGCACCAGTTAGACTCTGCTTTTATTTGCAAGGCAAGGAAAGAAAGGGAAGAATCATAATTTTTTTACAGGATTATTTTGGGGGCTACAGGAGACAATGTTCAAGAGCTAGCCAGATGTCTCATCAAGGAAGGCCTGTAAAACCACTGAGGGCCTTTTGGAAAAGGAATTGTTGACTTGGCCAGATTGGCATTTAAAAAAATTACCCTGATAATTGAAGAAACAATTAAAAGGGTGGAAGAGATAAAATATAGGGAACTTTTGCAATAGCCCAGTTGAAAGAAGTTCTTGGTTTGACTAGAAGGTTGGGCAGTAGGAAGAAATCAGACAAGCAGCCCCAAGAGGCTACATGAGAAAATGGAACAAAGGACTAAAGAAAAGCTGTGATGGAGCCCAGCATGCTGCCACCACCTCATCCGTTTGAGACAAATAGGAGAGTCTTGAACTCACACCGTCCTTGCAACTCAACCCCAATACAGCCTGTCCCTTTGTTTGAATTATATCATCACCTCCTACCTGCAGTGAGCCACAGGACTCATGTCTGTTTGAAACTAATATTATGTTTCTGCAGACACCTGTTCACCTCTGTTTGGAATGAGAATGAAAGGAACCTCTGACTACATAACCATGAACTGAGCCACTTTTTCTCACTGCTTCCAAATTCTATAGACCCTGAATATCCATCATGCCTCTAGATATTTATCATATTTACTCAGCACATATTTTTGAAGTATTGCCACATTTTCATATTTCATCTCCATGCCTCCCCTAAATATTAGGTGGCTATAGCCTAAATATTTAATAAAACTGTGGCTCAGTAAAGTTAGGAAACATTTTTAATGTGACCTGTTAGTAGAACAATAAGAAGACTGAATCCCCAGTTTCCAAAGTTTCTTTCTTTTTTTAATGTAATTGTGAAGTTTCTTGTTAGAGGGATTCTTTTCCAATGAAGATGAACTTGGAAGTTCCAGAGGTTTACATTAGCTCTATCTTAAAAGTTCATACCATTATATTTGTGACCGTGTGCCTTCTTTGTTTAATAGTTTATCATTCTACTGCTTCCTGAGAGTCCTAGGAAATAATGGCTAAGTGAGAATAGCTCTGAGAAAATCATAAATGCTAAGACAGACTTTTCTTTTGCTCCACAG
Seq C2 exon
CTTAGAAATTAGAGGTGATGCTAAAGAAAACAGCTGTATTTCCATCTCACAGACATCTGTGTATTCTGAGTACTGTAGTACAGAAATCAGATGGATCTGCCAAAAAGAACTAACACCTGTGAGAAATAAAGTGTATCCTGACTCTTGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000111796-KLRB1:NM_002258:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0005916=Lectin_C=FE(37.3=100)
A:
NA
C2:
PF0005916=Lectin_C=PD(34.3=70.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)