HsaINT0098957 @ hg38
Intron Retention
Gene
ENSG00000034152 | MAP2K3
Description
mitogen-activated protein kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6843]
Coordinates
chr17:21300545-21300993:+
Coord C1 exon
chr17:21300545-21300658
Coord A exon
chr17:21300659-21300873
Coord C2 exon
chr17:21300874-21300993
Length
215 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGC
5' ss Score
9.6
3' ss Seq
ATGGCAGTCCTTCCCTGCAGCGG
3' ss Score
7.01
Exon sequences
Seq C1 exon
AACTTTGAGGTGGAGGCTGATGACTTGGTGACCATCTCAGAACTGGGCCGTGGAGCCTATGGGGTGGTAGAGAAGGTGCGGCACGCCCAGAGCGGCACCATCATGGCCGTGAAG
Seq A exon
GTGAGCAGGGCCTGGAGGCAGCTGGGAGGGCTCCCTGGAGGAGGCGGGCTGAGCTCTGCCATGGGGCCCTGCCTATCCCTCTCAGTGATCAGTACCGAGGCTAGGCTTTTTGGGGCACACTGGGCAGTGGCCCCCTGAGCTCCTGGCCCTCCTGTCATGAGTGTGGGTGTTGGCCTCTGCCACGGCAACCTCTGAATGGCAGTCCTTCCCTGCAG
Seq C2 exon
CGGATCCGGGCCACCGTGAACTCACAGGAGCAGAAGCGGCTGCTCATGGACCTGGACATCAACATGCGCACGGTCGACTGTTTCTACACTGTCACCTTCTACGGGGCACTATTCAGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000034152:ENST00000342679:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=PU(11.1=76.3)
A:
NA
C2:
PF0006920=Pkinase=FE(14.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGAGGTGGAGGCTGATGACTT
R:
TCTCTGAATAGTGCCCCGTAGA
Band lengths:
228-443
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development