HsaINT0101543 @ hg19
Intron Retention
Gene
ENSG00000175221 | MED16
Description
mediator complex subunit 16 [Source:HGNC Symbol;Acc:17556]
Coordinates
chr19:868416-868946:-
Coord C1 exon
chr19:868863-868946
Coord A exon
chr19:868500-868862
Coord C2 exon
chr19:868416-868499
Length
363 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
3' ss Seq
CAGTGCCTGCCTCCCCGCAGGTG
3' ss Score
11.16
Exon sequences
Seq C1 exon
GGCCCCAGGCCAGCCCAAGATCGACCACCTGCGGAGGCTGCACCTTGGCGCTTGCCCCACGGAGGAATGCAAGGCCTGCACCAG
Seq A exon
GTGAGGGGCCCCCGGAACCGCTGACTCCCAGAGATGTGCCGCTGGGGATGGCTCAGCTGATTCTAGCCCCCACCCAGCGCTCCAGACGGTCAAGGGTGGTGGAGGGAGCACGTCCCAGAGGGAGTGTTGGAGCCAGGATCCCAGGATGTGGAGCAGTTAACTTGGTGTGGCGGGGCTAGTTCAGGGAGCAGCATTGCTGGGGGGAGGAGAAGCATGGGCAGAGGCCCTGTGGCAGGTGGGGACGTGGGGAGCAGGCGTGAGGGACGGCGAGCAGAGGGAGACCTGCCTGGAAGCAAAAGTGGGGCAGGCGTAAGGGAGGCCCGCCTGGAAGTGGGAACCCGCTCAGTGCCTGCCTCCCCGCAG
Seq C2 exon
GTGCGGCTGTGTCACCATGCTCAAGTCGCCCAACAGAACCACGGCGGTGAAGCAGTGGGAGCAGCGCTGGATCAAGAACTGCCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175221-MED16:NM_005481:14
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.009 A=NA C2=0.075
Domain overlap (PFAM):
C1:
PF116353=Med16=FE(3.9=100)
A:
NA
C2:
PF116353=Med16=FE(3.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)