HsaINT0101796 @ hg38
Intron Retention
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF like domains 11 [Source:HGNC Symbol;Acc:HGNC:29635]
Coordinates
chr15:65922338-65922969:-
Coord C1 exon
chr15:65922823-65922969
Coord A exon
chr15:65922473-65922822
Coord C2 exon
chr15:65922338-65922472
Length
350 bp
Sequences
Splice sites
5' ss Seq
GAAGTAAGG
5' ss Score
6.38
3' ss Seq
CATCTTCCCTTCACCCTCAGTCT
3' ss Score
8.52
Exon sequences
Seq C1 exon
GCATCCGCTGTGACAGCACGTGTCCACCTGGCCGCTGGGGCCCCAACTGCTCTGTCTCCTGCAGCTGTGAGAATGGAGGCTCCTGCTCCCCAGAGGATGGGAGCTGCGAGTGTGCCCCTGGCTTCCGAGGACCCTTATGCCAGAGAA
Seq A exon
GTAAGGCTAATCCCCTGACCCCGAAGAGCTCAGAGGGCTAATCCTCCCTAGCCCTCTCCAGTTGGAACTAGCCATGGCCTGAGAGAGGCTGGGCTCTTGAATCAGCCCCCATCTCTTCCTTCCCTCTAGTCTCTCCCTCTGCAGTTCTGTCCCCAGGTTTGGGGCCCAGCCCAGCTACTCAATGGAAACAGGGCCACACCACAGCTCTTCTCTGCAGAAAGGGATGCGCCCTCCAAGATGAGGGAAGGATGCAGGTCTCCCCATGTTTCTGAGAAGTGTGGAACAGGAAGGGTAGCTAGGCTGGCTGGGGTCTCTTGGGCTGCTGACCACCATCTTCCCTTCACCCTCAG
Seq C2 exon
TCTGCCCCCCTGGGTTCTATGGCCACGGCTGCGCCCAGCCATGCCCCCTCTGCGTGCACAGCAGCAGGCCCTGCCACCACATCAGCGGCATCTGTGAGTGCCTCCCAGGATTCTCTGGAGCTCTCTGCAACCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890:ENST00000409699:14
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PU(68.8=66.0)
A:
NA
C2:
PF0005319=Laminin_EGF=PD(29.2=30.4),PF126612=hEGF=WD(100=28.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACAGCACGTGTCCACCTGG
R:
CTTGGTTGCAGAGAGCTCCAG
Band lengths:
270-620
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development