HsaEX6075435 @ hg38
Exon Skipping
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF like domains 11 [Source:HGNC Symbol;Acc:HGNC:29635]
Coordinates
chr15:65917966-65922969:-
Coord C1 exon
chr15:65922823-65922969
Coord A exon
chr15:65922338-65922472
Coord C2 exon
chr15:65917966-65918094
Length
135 bp
Sequences
Splice sites
3' ss Seq
CATCTTCCCTTCACCCTCAGTCT
3' ss Score
8.52
5' ss Seq
AAGGTACTG
5' ss Score
8.56
Exon sequences
Seq C1 exon
GCATCCGCTGTGACAGCACGTGTCCACCTGGCCGCTGGGGCCCCAACTGCTCTGTCTCCTGCAGCTGTGAGAATGGAGGCTCCTGCTCCCCAGAGGATGGGAGCTGCGAGTGTGCCCCTGGCTTCCGAGGACCCTTATGCCAGAGAA
Seq A exon
TCTGCCCCCCTGGGTTCTATGGCCACGGCTGCGCCCAGCCATGCCCCCTCTGCGTGCACAGCAGCAGGCCCTGCCACCACATCAGCGGCATCTGTGAGTGCCTCCCAGGATTCTCTGGAGCTCTCTGCAACCAAG
Seq C2 exon
TGTGTGCTGGAGGATACTTTGGGCAGGACTGTGCCCAGCTCTGCTCCTGTGCCAACAACGGGACCTGCAGCCCTATCGATGGCTCCTGCCAGTGCTTTCCTGGATGGATTGGCAAGGACTGCTCACAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890-'33-45,'33-41,34-45
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PU(68.8=66.0)
A:
PF0005319=Laminin_EGF=PD(29.2=30.4),PF126612=hEGF=WD(100=28.3)
C2:
PF0005319=Laminin_EGF=PU(69.0=65.9)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGCACGTGTCCACCTGG
R:
GTCCTTGCCAATCCATCCAGG
Band lengths:
253-388
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains