HsaINT0101800 @ hg38
Intron Retention
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF like domains 11 [Source:HGNC Symbol;Acc:HGNC:29635]
Coordinates
chr15:65915470-65916276:-
Coord C1 exon
chr15:65916148-65916276
Coord A exon
chr15:65915599-65916147
Coord C2 exon
chr15:65915470-65915598
Length
549 bp
Sequences
Splice sites
5' ss Seq
AGAGTAAGC
5' ss Score
6.31
3' ss Seq
TAACTCTTTGTGCCACACAGGAT
3' ss Score
6.74
Exon sequences
Seq C1 exon
GCTGCCCAGCAGCATTTTTTGGGAAGGACTGTGGGCGCGTATGCCAGTGTCAGAATGGCGCCAGCTGTGACCACATCAGTGGCAAGTGCACCTGCCGCACAGGCTTCACCGGGCAACACTGTGAGCAGA
Seq A exon
GTAAGCTGCCCTGACCCCTGATCCTGGGTGATGCTGCTGGGCCCTACCCTCCTGCAGAGGATGGCTCCCACTTCAAGGTCCACTCACTCAGGGCTCTGTACCCCTTGGTCCCTTGACTTTGGGGACAACTTCCAAGGAAAAATGCTGAGGAAGGTCATGCCTACATTATTGTTTGAAGAATTTCTCCCTTCAGTTGGTGGGGGCATTTAGGGCAGAGGTCATAGCAAGTAATGAGAGAATAGTGGGAGGCAGGATTTTTTTTTTATTATTCTTTAAAGTCCCTATGGCATTCAGATTAGGGCATGGCAGGTGGAAGATACTGCTTAAATGTGTTGCATGAGGAGGAAGTAGGGGTGAGTGGGCCCTGCTCACTCCTCCTCTGTCCCTGTGTCCCCCACTCAGTGCTATAAATGCTCCTCAACAGGAGCTAAGGGAATAGGCTTCACTCAGTGGGAGGCAAAACAGGCTTATTGCCATAGCTGTCTAAACATGGAAGGGGAGGGGTGGAGAGTGAGTGGGTCCTCTACCCTAACTCTTTGTGCCACACAG
Seq C2 exon
GATGTGCCCCAGGAACCTTTGGCTATGGGTGTCAGCAGCTATGTGAGTGCATGAACAACTCCACCTGTGACCATGTCACCGGCACCTGTTACTGCAGCCCTGGCTTCAAAGGAATCAGGTGTGACCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890:ENST00000409699:18
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.055 A=NA C2=0.025
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PU(63.0=65.9)
A:
NA
C2:
PF0005319=Laminin_EGF=PD(34.8=36.4),PF0005319=Laminin_EGF=PU(78.4=65.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTTTTGGGAAGGACTGTGGGC
R:
TCACACCTGATTCCTTTGAAGCC
Band lengths:
238-787
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development