HsaEX0038730 @ hg38
Exon Skipping
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF like domains 11 [Source:HGNC Symbol;Acc:HGNC:29635]
Coordinates
chr15:65915470-65916956:-
Coord C1 exon
chr15:65916828-65916956
Coord A exon
chr15:65916148-65916276
Coord C2 exon
chr15:65915470-65915598
Length
129 bp
Sequences
Splice sites
3' ss Seq
TGGAAATCCTGTTTCTCTAGGCT
3' ss Score
6.43
5' ss Seq
AGAGTAAGC
5' ss Score
6.31
Exon sequences
Seq C1 exon
CTTGCCCACCCGGGTTCTGGGGCCCCGCCTGCTTCCACGCATGCAGCTGCCACAACGGGGCGAGCTGCAGCGCCGAGGACGGGGCCTGCCACTGCACCCCTGGCTGGACTGGACTCTTCTGCACACAGC
Seq A exon
GCTGCCCAGCAGCATTTTTTGGGAAGGACTGTGGGCGCGTATGCCAGTGTCAGAATGGCGCCAGCTGTGACCACATCAGTGGCAAGTGCACCTGCCGCACAGGCTTCACCGGGCAACACTGTGAGCAGA
Seq C2 exon
GATGTGCCCCAGGAACCTTTGGCTATGGGTGTCAGCAGCTATGTGAGTGCATGAACAACTCCACCTGTGACCATGTCACCGGCACCTGTTACTGCAGCCCTGGCTTCAAAGGAATCAGGTGTGACCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890-'39-48,'39-47,41-48
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.002 A=0.055 C2=0.025
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PD(28.6=27.3)
A:
PF0005319=Laminin_EGF=PU(63.0=65.9)
C2:
PF0005319=Laminin_EGF=PD(34.8=36.4),PF0005319=Laminin_EGF=PU(78.4=65.9)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTGCTTCCACGCATGCAG
R:
TCACACCTGATTCCTTTGAAGCC
Band lengths:
226-355
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development