HsaEX0038732 @ hg38
Exon Skipping
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF like domains 11 [Source:HGNC Symbol;Acc:HGNC:29635]
Coordinates
chr15:65916148-65918094:-
Coord C1 exon
chr15:65917966-65918094
Coord A exon
chr15:65916828-65916956
Coord C2 exon
chr15:65916148-65916276
Length
129 bp
Sequences
Splice sites
3' ss Seq
GCATTTCACCGACATCCCAGCTT
3' ss Score
0.27
5' ss Seq
AGCGTAAGC
5' ss Score
6.06
Exon sequences
Seq C1 exon
TGTGTGCTGGAGGATACTTTGGGCAGGACTGTGCCCAGCTCTGCTCCTGTGCCAACAACGGGACCTGCAGCCCTATCGATGGCTCCTGCCAGTGCTTTCCTGGATGGATTGGCAAGGACTGCTCACAGG
Seq A exon
CTTGCCCACCCGGGTTCTGGGGCCCCGCCTGCTTCCACGCATGCAGCTGCCACAACGGGGCGAGCTGCAGCGCCGAGGACGGGGCCTGCCACTGCACCCCTGGCTGGACTGGACTCTTCTGCACACAGC
Seq C2 exon
GCTGCCCAGCAGCATTTTTTGGGAAGGACTGTGGGCGCGTATGCCAGTGTCAGAATGGCGCCAGCTGTGACCACATCAGTGGCAAGTGCACCTGCCGCACAGGCTTCACCGGGCAACACTGTGAGCAGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890-'38-47,'38-46,39-47
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.002 C2=0.055
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PU(69.0=65.9)
A:
PF0005319=Laminin_EGF=PD(28.6=27.3)
C2:
PF0005319=Laminin_EGF=PU(63.0=65.9)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATACTTTGGGCAGGACTGTGC
R:
CTGCTCACAGTGTTGCCCG
Band lengths:
244-373
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development