HsaINT0101798 @ hg38
Intron Retention
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF like domains 11 [Source:HGNC Symbol;Acc:HGNC:29635]
Coordinates
chr15:65916828-65918094:-
Coord C1 exon
chr15:65917966-65918094
Coord A exon
chr15:65916957-65917965
Coord C2 exon
chr15:65916828-65916956
Length
1009 bp
Sequences
Splice sites
5' ss Seq
AGGGTAAGC
5' ss Score
9.04
3' ss Seq
GCATTTCACCGACATCCCAGCTT
3' ss Score
0.27
Exon sequences
Seq C1 exon
TGTGTGCTGGAGGATACTTTGGGCAGGACTGTGCCCAGCTCTGCTCCTGTGCCAACAACGGGACCTGCAGCCCTATCGATGGCTCCTGCCAGTGCTTTCCTGGATGGATTGGCAAGGACTGCTCACAGG
Seq A exon
GTAAGCTGCTGCCACCTGGGAATGCCCCTACCTGGGGTCAGGCCCAAAAATTCTCCCTTTGTTGCCCAAAACCTCTCTGTCCTGGTGCCTCCACTTCCAGGGATGAAATCTCCTTCTGCATGTAGGAATGAGCCCCATTTAGCTCTATAGCTAACATGATGGATTATTAGGATTGATCATTGGTATTAACTGCTGGTATCAAAGGTACTGATATTGTTGATAGTACCATTAATGCTATGAATTCTGAGACTTAACACTCCATTAGCACCTGCACAAGGAGCAGCCCGAGTTTGGATGGGGAAGAGGTGGTGCAACAGCATGCTCGAGTTTGGGAGTAGGGAAGTGAGATGAGGCCCGGGCAGCCACCTCAGGAGGGTGCAGTGCCCTCTGGGTGGCCCATGTGAATGATGTCCTTGAGGCTGTTCATGTAAAGTGCACCAATCTGATGTGAAGGGAACAGCCCCTTTCCAGAAGCCCCCAAACTAAGGACAGAGACCCTGTGGAGCTCCTTGTCTGATGGGTGAGACCTAGCCAGTACCCTTGGGGAGGTCCTAGTTAGATGGCTGAGGGAATTTCCATTCTGATGAGGAGACAGGCTCCATCATCAGGAGCTCACCAACTGAGAGAAGAGAGCTCCTGCCCTAGGAAAGTCCCCATTCTCATGGGGAAACACACACAGTACATACACGGTAAACCACAGTGTTTACCCGCATGCTCCAAATCAGTCCCCTGAGAGGGGAGGCTCGGGGGCCCTCAGAGTCCTGCTGAGTCAGTCATCAAAGACTTGGAGAGTGGGCAGAGAATCTGGGCTTAATGGGAATCCTGGGTAACTAAGCCAAGAAGTAAGTGCAGGAATTCTGGGAACAGTGCATGAAGCCCCTGAAAGCCAGGAAATGTCAGCCAGGTCCATCTTGGCATCTTGGCTCTGACATGTACTCCCCCTTCTTCTCCCTCTCCGTCTGCCCCTCTCTGCCTTCCCCTCACCCTCTGCATTTCACCGACATCCCAG
Seq C2 exon
CTTGCCCACCCGGGTTCTGGGGCCCCGCCTGCTTCCACGCATGCAGCTGCCACAACGGGGCGAGCTGCAGCGCCGAGGACGGGGCCTGCCACTGCACCCCTGGCTGGACTGGACTCTTCTGCACACAGC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890:ENST00000409699:16
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.002
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PU(69.0=65.9)
A:
NA
C2:
PF0005319=Laminin_EGF=PD(28.6=27.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGATACTTTGGGCAGGACTGTG
R:
GCTGTGTGCAGAAGAGTCCAG
Band lengths:
247-1256
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development