HsaINT0101829 @ hg19
Intron Retention
Gene
ENSG00000162591 | MEGF6
Description
multiple EGF-like-domains 6 [Source:HGNC Symbol;Acc:3232]
Coordinates
chr1:3415262-3415830:-
Coord C1 exon
chr1:3415702-3415830
Coord A exon
chr1:3415391-3415701
Coord C2 exon
chr1:3415262-3415390
Length
311 bp
Sequences
Splice sites
5' ss Seq
AGGGTAAGC
5' ss Score
9.04
3' ss Seq
TCCCTCTTCCCTGGCCCCAGCCT
3' ss Score
6.51
Exon sequences
Seq C1 exon
CCTGCCCAGCCCACACCTACGGGCACAATTGCAGCCAGGCCTGTGCCTGCTTTAACGGGGCCTCCTGTGACCCTGTCCACGGGCAGTGCCACTGTGCCCCTGGCTGGATGGGGCCCTCCTGCCTGCAGG
Seq A exon
GTAAGCCACATCTAGGAGTCCAGGGACCGGGGTCCAGGCCTGAGCGAGGGTGCTGGCCTCTTGCAGGGCCCACAGGACACTTGGTGCCTGGGGGAGGGAGGAAGGGGCTGTTAGGACTGAGGACCGTGCCTTTCACCTGTGCCCCTCTCCAGGCAGGGATGGGGAGTGAGGCTGGGCTGGCAGGTCATCCTAGGGGCAGCCCCCTGCAAGGTGCCTGACCCCAAAGTCCAACATGGGGCTGGAAAGCCAGACAGACCCTGTGGGGCCAGCTGGCTGGGGGATGCAGGTTGCTCCCTCTTCCCTGGCCCCAG
Seq C2 exon
CCTGCCCTGCCGGCCTGTACGGCGACAACTGTCGGCATTCCTGCCTCTGCCAGAACGGAGGGACCTGTGACCCTGTCTCAGGCCACTGTGCGTGCCCAGAGGGCTGGGCCGGCCTGGCCTGTGAGAAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162591-MEGF6:NM_001409:24
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF126612=hEGF=WD(100=29.5)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGCCCAGCCCACACCTA
R:
CCTTCTCACAGGCCAGGC
Band lengths:
257-568
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)