DreINT0014411 @ danRer10
Intron Retention
Gene
ENSDARG00000074808 | MEGF6 (1 of 2)
Description
multiple EGF-like-domains 6 [Source:HGNC Symbol;Acc:HGNC:3232]
Coordinates
chr11:41127032-41127555:-
Coord C1 exon
chr11:41127427-41127555
Coord A exon
chr11:41127161-41127426
Coord C2 exon
chr11:41127032-41127160
Length
266 bp
Sequences
Splice sites
5' ss Seq
AGCGTAAGA
5' ss Score
6.21
3' ss Seq
TAATATTTGTGTTTCCGCAGGCT
3' ss Score
9.99
Exon sequences
Seq C1 exon
CGTGTCCTGCGGGATGGTTTGGCGTGAGCTGTTCTCAGACCTGTGTTTGTCACAATAACAGCAGCTGTGATGCAGTGAGCGGTCAGTGTGAATGCGGTGCAGGCTGGACAGGAGACACATGCTCACAGC
Seq A exon
GTAAGACACTGACCAGACATTCATGCTACAGTTACTATAAACACAATGCTGATGCTATACATCTAAACTGAATCTATTGTCATTGTGAAATCAATCAAAATGTGATGGGGATACGTCTGATTCTGGAACTTTTAAACCAAAACAGACTTTACATTTTCTAGCATTTTGTGATTTAGCTCAGGATGCTAACCTCACGTGTGGTAGCACATGGCATGTTTAAGTCAGATTTTGTATGTATTTTTCACATAATATTTGTGTTTCCGCAG
Seq C2 exon
GCTGTCCTGCAGGTGTGTTCGGGGACGGTTGTGTTCACAGGTGTTTGTGTCAGAACGGGGCCTCGTGTGACCCTGAGAGTGGACACTGCTTCTGTCCTAGCGGCTGGACGGGGGCCGCCTGTCAGCTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000074808:ENSDART00000109204:25
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PU(65.9=65.9)
A:
NA
C2:
PF0005319=Laminin_EGF=PD(31.8=31.8),PF079748=EGF_2=WD(100=68.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGTCCTGCGGGATGGTTTG
R:
TCCAGCCGCTAGGACAGAAG
Band lengths:
236-502
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]