HsaINT0101834 @ hg38
Intron Retention
Gene
ENSG00000162591 | MEGF6
Description
multiple EGF like domains 6 [Source:HGNC Symbol;Acc:HGNC:3232]
Coordinates
chr1:3495890-3496783:-
Coord C1 exon
chr1:3496655-3496783
Coord A exon
chr1:3496019-3496654
Coord C2 exon
chr1:3495890-3496018
Length
636 bp
Sequences
Splice sites
5' ss Seq
TCAGTGAGT
5' ss Score
7.68
3' ss Seq
CACCACTTCCTCCCCGGCAGCCT
3' ss Score
6.22
Exon sequences
Seq C1 exon
GATGTCCGCCCGGGCGGTATGGGCCAGGCTGTGAACAGCTGTGTGGGTGTCTCAACGGGGGCTCCTGTGATGCGGCCACGGGGGCCTGCCGCTGCCCCACTGGGTTCCTCGGGACGGACTGCAACCTCA
Seq A exon
GTGAGTGGCTGGTGGCAGCAGTGCTGAGTGGCGCCTCCTGTGTCTCCAGGGTAGGGCCAGCCAGCCTGCAGGAGGATGGCCCCCGACTGCCCACCTCCCTGCCCTTCAGCCCCCTCTGGCTGGGCCTGGCCCCAAGTGGGGCTAAGCCAGAGGGGCAGAAAGGACCTGCAGCGCTGGGGGTGTCTATGTGGCCCCAGGTCCCACAGGCTTCTGCTAGCTCTGCCCCTGCACCTGCTGTGCCCGGCGACCTGCGCCATGTCTGCCAGGGGCTTGAGCACAGCCAGGCACAGAGGTCAGCCAGGCAGCTCAACTGTGGCCAAGCGTCCTGCTGGGAAACGGGCCTCTTCCCTCAGTCATGCAGGGACTTTCCCCTTCTGGGACCCCAGCAGAGCTGGCGGGGTGGGCGGGGGTGGCAGTGAGTCACTGCAGAGCAGGCGGCAGTGGCCTGGCCCCCAGCAGGCCTGCGGGTGGAAGGGAGATGCCAGGGTGGGTGCATGAGAGTTGGCTGGCCCCACCCTGTCTGGGGCAGACCCAGGGTCCCCTCACCCCATCCCATCCTGTCCTATCCCCACTCCGGGGTTGACCGGGCAGGGAGAGAAGGGAAGCCAGCCACGATCACCACTTCCTCCCCGGCAG
Seq C2 exon
CCTGTCCGCAGGGCCGCTTCGGCCCCAACTGCACCCACGTGTGTGGGTGTGGGCAGGGGGCGGCCTGCGACCCTGTGACCGGCACCTGCCTCTGCCCCCCGGGGAGAGCCGGCGTCCGCTGTGAGCGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162591:ENST00000294599:23
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.236 A=NA C2=0.120
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PD(34.0=36.4)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTATGGGCCAGGCTGTGAAC
R:
CGGTCACAGGGTCGCAGG
Band lengths:
194-830
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development