HsaINT0101834 @ hg19
Intron Retention
Gene
ENSG00000162591 | MEGF6
Description
multiple EGF-like-domains 6 [Source:HGNC Symbol;Acc:3232]
Coordinates
chr1:3412454-3413347:-
Coord C1 exon
chr1:3413219-3413347
Coord A exon
chr1:3412583-3413218
Coord C2 exon
chr1:3412454-3412582
Length
636 bp
Sequences
Splice sites
5' ss Seq
TCAGTGAGT
5' ss Score
7.68
3' ss Seq
CACCACTTCCTCCCCGGCAGCCT
3' ss Score
6.22
Exon sequences
Seq C1 exon
GATGTCCGCCCGGGCGGTATGGGCCAGGCTGTGAACAGCTGTGTGGGTGTCTCAACGGGGGCTCCTGTGATGCGGCCACGGGGGCCTGCCGCTGCCCCACTGGGTTCCTCGGGACGGACTGCAACCTCA
Seq A exon
GTGAGTGGCTGGTGGCAGCAGTGCTGAGTGGCGCCTCCTGTGTCTCCAGGGTAGGGCCAGCCAGCCTGCAGGAGGATGGCCCCCGACTGCCCACCTCCCTGCCCTTCAGCCCCCTCTGGCTGGGCCTGGCCCCAAGTGGGGCTAAGCCAGAGGGGCAGAAAGGACCTGCAGCGCTGGGGGTGTCTATGTGGCCCCAGGTCCCACAGGCTTCTGCTAGCTCTGCCCCTGCACCTGCTGTGCCCGGCGACCTGCGCCATGTCTGCCAGGGGCTTGAGCACAGCCAGGCACAGAGGTCAGCCAGGCAGCTCAACTGTGGCCAAGCGTCCTGCTGGGAAACGGGCCTCTTCCCTCAGTCATGCAGGGACTTTCCCCTTCTGGGACCCCAGCAGAGCTGGCGGGGTGGGCGGGGGTGGCAGTGAGTCACTGCAGAGCAGGCGGCAGTGGCCTGGCCCCCAGCAGGCCTGCGGGTGGAAGGGAGATGCCAGGGTGGGTGCATGAGAGTTGGCTGGCCCCACCCTGTCTGGGGCAGACCCAGGGTCCCCTCACCCCATCCCATCCTGTCCTATCCCCACTCCGGGGTTGACCGGGCAGGGAGAGAAGGGAAGCCAGCCACGATCACCACTTCCTCCCCGGCAG
Seq C2 exon
CCTGTCCGCAGGGCCGCTTCGGCCCCAACTGCACCCACGTGTGTGGGTGTGGGCAGGGGGCGGCCTGCGACCCTGTGACCGGCACCTGCCTCTGCCCCCCGGGGAGAGCCGGCGTCCGCTGTGAGCGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162591-MEGF6:NM_001409:29
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.240 A=NA C2=0.124
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PD(34.8=36.4),PF079748=EGF_2=WD(100=70.5)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTATGGGCCAGGCTGTGAAC
R:
CGGTCACAGGGTCGCAGG
Band lengths:
194-830
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)