HsaINT0101845 @ hg19
Intron Retention
Gene
ENSG00000162591 | MEGF6
Description
multiple EGF-like-domains 6 [Source:HGNC Symbol;Acc:3232]
Coordinates
chr1:3431114-3432091:-
Coord C1 exon
chr1:3431966-3432091
Coord A exon
chr1:3431237-3431965
Coord C2 exon
chr1:3431114-3431236
Length
729 bp
Sequences
Splice sites
5' ss Seq
TCCGTGAGT
5' ss Score
8.93
3' ss Seq
CCTCGGGCCCGTGGCTGCAGGTA
3' ss Score
6.01
Exon sequences
Seq C1 exon
CCATTAACTCCTGCGCCCTGGGCAATGGCGGCTGCCAGCACCACTGTGTCCAGCTCACAATCACTCGGCATCGCTGCCAGTGCCGGCCCGGGTTCCAGCTCCAGGAGGACGGCAGGCATTGTGTCC
Seq A exon
GTGAGTGCTGCCAGCCTGGGAGGGAGGACCTGGGGGTGGAGGCAGGACAAGCTGCCTCGCCTGGGCTGTTGGGTGGAAGTGGGTCTTCAGGAGGCCCCCAAGGCTGCTGAGAGGCCTGGTAGGGATGGCACATTTGGGGCCAGGAAGCTCAGGATGGGGGCCACCTCACTTCCATAGGTGCCCACCTGAGGCTTGCTGCCCTTGGGAGGAGGAGGCAGGCCAGTCCGGTTTGGCACTTTGCTCTGAGTCCTCAGGGCTGCTTGCGTGGAAAGGGGGGGCTTTGCTGATGGTGACGGTGCGGCAGACTCAGTGGTCCTCCAGAATATGGAAATGGGGGCTGTGGGTGGGGCAGGTGCTGAGAGAATGCCCCCACCTGGGCCTCTGGGTCCTCCCCAGTGTGGGCATGAAGGGGCTGGAGTCACAGAGCTGGGGGGCCGCCGCCTTGGTGTCAGCGCCAGCACCTGGGCTAAGAAGGGTGGTGGGAGGAGCTGGCCTGGGCCGCTGCCTGACCTGGGCTGGCTGGCCGCGTCCTGAGACTGCAGAGTCTTCTCGGCGTCTTGGGGGCTTCCCGCACCTGGGAGGAGGGAGACCCGCTGCCCAGCCCATCAGCCTGGAGCACAGAGTGGGGAGAGCACTGGGTGAGGGGTCTCACAAGAAGCCTGGGGGCAGGCGCCCTGCAGCCACTGGGGTCCCCTCTCCCCAACCCCCTCCTCGGGCCCGTGGCTGCAG
Seq C2 exon
GTAGAAGCCCGTGTGCCAACAGGAACGGCAGCTGCATGCACAGGTGCCAGGTGGTCCGGGGCCTCGCCCGCTGTGAGTGCCACGTGGGCTATCAGCTAGCAGCGGACGGCAAGGCCTGTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162591-MEGF6:NM_001409:6
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF146701=FXa_inhibition=WD(100=86.0)
A:
NA
C2:
PF146701=FXa_inhibition=WD(100=85.7),PF0764510=EGF_CA=PU(0.1=0.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CATTAACTCCTGCGCCCTGG
R:
CTTGCCGTCCGCTGCTAG
Band lengths:
238-967
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)