DreINT0014428 @ danRer10
Intron Retention
Gene
ENSDARG00000074808 | MEGF6 (1 of 2)
Description
multiple EGF-like-domains 6 [Source:HGNC Symbol;Acc:HGNC:3232]
Coordinates
chr11:41149356-41153153:-
Coord C1 exon
chr11:41153028-41153153
Coord A exon
chr11:41149479-41153027
Coord C2 exon
chr11:41149356-41149478
Length
3549 bp
Sequences
Splice sites
5' ss Seq
CATGTGAGT
5' ss Score
7.83
3' ss Seq
CCTGTATTGACCATCATCAGTGG
3' ss Score
2.28
Exon sequences
Seq C1 exon
CTGTTCAGTCCTGCGGCGTTGGGAATGGCGGCTGTGAGCATTTCTGTGTCCAGCAGACGGCGGGTCATGTCCAGTGTCGCTGCAGACCTGATTACAGACTGGACGCGGATGGAAAACACTGCACAT
Seq A exon
GTGAGTCTGAATGCATGATCATTTATGACACCGTTTTACACTCTTGTTGACAATGGATGTAGGCTGAATTTAAAGGCAAAGATGTCAGGGTTTCAGGAAGGATGAGGGAGCGAGGACTCAAATGCAACATAAGATGGTATTTAATAATAAAAATAAAACAAAAAGGACAACAAAAACTACCCCAAGGGGGAAAACATAACTATAAAACAAACAATCAAACAAACTTGGATGGGCTGGCAAGACAAACAGGACTGGATAGCACAGGACATGAAAATAACGACGACGAACTGGCAAAGGACTGAAAACATGAGGGGATTATAAAGCAAAAAGTAAATTGACACACAGGTGAACATGACAAACTAATAATGAGTAAACAAGGAGGGTGGGACTAGACAATAGACGGGAGAGCGCATGACACAGAGAGACAATACAAGCCATGCGCTCACATAACACAACACTGAAGCACACGACAAAAGCACGTGACCACAATGTAAACACCGAGCCACGTGCTTTGACAAGAGACGCAAGACACGAGCACACGATGAATGAAAACACTCACCGTGCGCTCACACACGCAGCGTGCATGCTTCATCCCAGCGACGACCAAAACCGAAACCAACAAGACTGAGACGCTGGGAATGAAACACCACGCTGCTGACAGACGAAAACACAAACACGAGTACAAGAGCGCGCGCGCTCTGCCGCGTCAAGCAGGAGCGCGCACACTCTTCGTACACCCACGACGGCGCGCGCGCACAGAGACAGAAACAGGACCAGACATGGGTAGTGTCCGAGCTCTGCCACCAAAACAAGAATTTACAAGACCAGAGTGGCAGAACCCTGACAAAAGATGTTTTTCTTAAAGAAGAGGATGCAAAAAATCATAATAATACATTAAAAAACTGTATTAATTAGTTCTTCTTCGGAAAACAAAAGCAGAGATTGAAGGCTCTGAAGTTTTAACAGGACAAAAACACCATAAAATTAGTCACAAAATTGTATTAGAGGTTTTGGAAAGCCACGAGACAACTTGTATTGAGTAAAACTGCAGTTATTATTTATTACAAACATTTCAAATGAAGAATTGTGAGGATTTTTAGAGAGAAATACAACTTGGTGAGAAATTGTGTTAAATTGAGTTTTTTTATGACTTTGTGAGACGTGAAATGCAGAAAGTTATGAGGAGTATTTGTATAAATCTCCCTTGGTTCTTTTTTTGTTTTAAATTATGCATAAAGTGCAAGGATAGGATGATATTTTTTGTTTTTATAGTTATAATTGCTTTCAGCTGCTCTTAATTCTTGTTAATTAATCTGCACGCATAGATATGAATGAGATTGCATGATAGAGCCCTTTGTTGGAAGTCAAAGCATTTGTTAAACATCGCTGACACGTATTGCATAAATATTACCATTCCCTGACTCTCGAAATCATGATAAATGTCCCAATGACAGAGAATTAAACAGTGCAAGTACTCTAAAACATCCTTTTTTAATGTCTTATTATTCAAATATCTCTTCACAAGTGCTCTCTTCCTTTGAAACGACCGCCAAAAAATCCCAAGAGCTGATTTAGTGAAATTATGAGTTGGGATGAAGTTGTCCTTTGATTCACTACGTGACGTAATCTCACAAACTGTGACATCAGTGTCTTTGTGTCTGGTTTTCTGAGGTCGTCTTGAGTTGAATACTGAATTTAGAGAGATTTCTGCTGTTTCTGTTCCTGTGAAAGTGTAATTGTTGGCAAGGGAGAGCTTGTTTTACTGTAGTTGAACACTGTGAGCGTGTGACAGGAGTTATTCGCAGCAGCTGGATGGCTCATGGGAAATCTGTTGAATATCGTACACTGCAAAAAATGCTTTTCTTACTTTGTTTTTGTCTTGTTTCTAGTTCAAACATTAACAATTCTTAAATCAATAAGCATTTTCCAGATGTTACGATTTAATAAGTTATCTAGGGAGATTAAACGTAACACTTAGAATATTAGATAATTACTGGAGTAGATGGATGGAAAATACACAAGGACACGAGTTTAGCAATTAATTCGTTTATGCAGACATGGATGTGCAGACATTTCTGGAGACCGCGATTTACGTAGCTGGAGGTACGTATGGCTGCATTTAGTTTTTTCAAGTGAACGCTACAGGGCGGTGTGATGCCGCTCCTCTTCGCGCTCGCCGGCTGACGGCTCACCTCCTCCTTGTGGAGGGCTTTCCCGCTGCAACCAGTTTGTCTGGTTAGCTCATCGTGTTACGTCGGCGGAGCGGAGACCCAGAGGAGGAGCCGGCCGCGGCGACGACCGGGTTCGAGCCCCGTGAAGAGCGGTTCCAGAAATTAGGTAAGACGAAAAAAACAAAATCCAAAAAATAAACCGAACGGGTTCGTAACGGGGCGAGAATGCGGTGAAATCCGAAAACGCGGTCAAAATCGCATGAGGGCTTTTCTTTAACTGGACGGCTTTTGTAAATCATCGCTTGGGTTTAGGGAAGGAAGAGGAGGAGGGTGTCTGGGTCGGCTGATTGGCTGGCCACCCAGTCAATCGTTCAGTCAGTCAGTCAGTCAGACAGACAATCGCTCGACATCATCCTCCGGCAGCTTTATACGAGAGAGCAGCGCGGGCGCGAACAGTGCGCGAAAGGTGTTCGCAACGTAAAAGCGCGCACATCGTCCTCTCGCGGATTAGTGAAAACAAAATCTGCAAAAACTGCCTAGGATGTATTTCACGGTCTCCAGAAACGTCCGCGGGGCTACGTTTCCAGAATGAGCCTGGGTTGCATTTATTCCTCCTATAAGGGAAAGAGAGATGAGGCCAACGGAAGAGAGGCTTATTTGTGTGCGCTTTGTACAATGCATAAAAAAAGCAAACAGAAATACAATCAAACCAAAAGTTTCAGGGTGCCAAAGCAAAAGCAAAGAACTAAACAAAACCAAAAGCCACCTAAACTACAACACAAGATCCCCTCTAAACTTACTATTCATTCATTTTCTTGTCGGCTTAGTCCCTTTATTAATCTGGGGTCGCCACAGCGGAATGAACCGACAATTTATCCAGCAAGTTTTTATGCAGCGGATGCCTTTCCAGCCGCAACCCATCTCTGGAAAACATCGACACACACATTCACACACACACACACACACACTCATACACTACGAACAGTTTAGCCTACCCAATTCACCTGTACCGCATGTCTTTGGACTGTGGGGGAAACCGGAGCACCTGGAGGAAACCCACGCGAACATGGGAGAACATGCAAACTCCACACAGAAACACCAACTGAGCAGAGGTTCGACCCAGCGACCTTCTTGCTGTGAGGCGAAAGAACTACCTACTGCACCACTTCCTCGCCATAAACTTACTAATGAAAATCAAAATGTGAAAAAGAAACTGAAATCTTCATCGTAAGCAAGGCCAATAACACAAGCTCCCTGAAACAATAAACAAAAACACAAAAACCACTAAACTAGCAAAATGAGCTGAAAAAAATCAATATGGTTAGTTTTGATATCATGTGTACTTTAATACCTGATATCCTGTATTGACCATCATCAG
Seq C2 exon
TGGTGAACCCGTGTGCGGAGCAGAATGGCGGATGTTCTCAGATGTGTCATAGGGATGGAGCTCAGGCCCGCTGTGAATGTCATCCAGGTTATCAGCTCGCTGAAGACGGCAAGACATGTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000074808:ENSDART00000109204:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF146701=FXa_inhibition=WD(100=86.0)
A:
NA
C2:
PF146701=FXa_inhibition=WD(100=85.7),PF0764510=EGF_CA=PU(0.1=0.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]