HsaINT0102224 @ hg38
Intron Retention
Gene
ENSG00000138382 | METTL5
Description
methyltransferase like 5 [Source:HGNC Symbol;Acc:HGNC:25006]
Coordinates
chr2:169812457-169815528:-
Coord C1 exon
chr2:169815477-169815528
Coord A exon
chr2:169812507-169815476
Coord C2 exon
chr2:169812457-169812506
Length
2970 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
3' ss Seq
AGGTGGCTTTTGTTTTACAGAAC
3' ss Score
8.05
Exon sequences
Seq C1 exon
CATGTTCAAAAGAAAGCTGCAGAATGGAAAATCAAGATAGATATTATAGCAG
Seq A exon
GTAAGACAAATCTCAATCCTAATATCCAAAAGGGCCAACATGTATTCGCCCAACCAAAATTTTCATGCAGGTGCTGAGAAGATAAACTATGCTTTACAGTGTGGCAAAATGTGCATGATTGGTAATAGATTGGAAATGGAGTAAAAGCAGAATGAACACTTAGCCTGAGACTGTCCTAATTTATGCGATTTACTGAAAATTTCTAATAGCACTCAGGTATTTGGTCACTCCAGACTCAGGCAGAACACTGTATAGCAGCACAATGGCTAAAAACATGGGCTGGGGGCCAGGTGTGGTGGCTCACGCCTGTAATCCTAGCACTTTGGGAGGCCAAGGTGGGCAGATCACCTGAGGTTTGGAGCTCAAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATATAAAAAATTAGCCAGGCATGGTGGCGCACACGTGTAATCTCAGCTACTTGGGAGACTGAGGCGGGAGAATCGCTTGAGTCCCAGAGGCAGAGGTTGCAGTGAGCCGAGATCGCACCACTGTTCTTCAGCCTGGATGACAGAGGAGACTCAGTCTCAAAAAAACAAAAACAAACAAATGAAAAAAAAAAGTGGGCCGGGCGCGGTAGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGCGGATCACGAGGTCAGGAAATTGAGACTATCCTGGCTAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAAATTAGCCAGGTGTGGTGGCAGGCACCTGTAGTCCCAGCTATTCAGGAGGCTGAGGCAGAAGAATGGTGTGAACCTGGGAGGCGGAGCTTGCAGTGAGCTGAGATCGCGCCACTGCTCTCTAGCCTAAGCAACAGAGTGAGATTCCATCTCAAAAAAAAAAAAAAAAGTGGGCTTGGAGTTGGTCAGATCTTGGTTTGAAATTCATTCATAGAAAATGCCACCACATTATTCCTAGATAATCTAATTTCATTTTCTTTTTTCTTTTTTTTTTTTTGAGACAAAGCCTTGCTCTGTTACCCAGGCTGGAGTGCAGTGGCAACCTCCACCTCCCGGGTTCAAGCGATGCTCTTGCCTCAGTCTCCCAAATAGTTGGGACTACAGGCATGCACTACCACGCCCGGCTAATTTTTTAATCTTTAGTAGAGACAGGGTTTCACCACGTTGGCAGGGCTGGTCTTGAACTCCTGACCTCAGTGATCCTCCAGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGAGCCCAGCCTCTAATTTCATTCTCTAATTACCCCTGGAATCAAATAACATTTATCTTTTTCTTCTAAATATCTATGAGTAAATCATGTTTGATACATTTTTATTACTAAATTGGGTAATAGTCACAAACATCAAAACAGGAAAAGCATATAACTAGAAGCTAATTATAATCTAAGCCTGAAATAAGAGTGCAATAAGGGAACATGTTTTTTCACAATAATAAACTAACAATGAATTGCCACTGTAGTGTTAAACATACAGCTAGATATATTACTGTTCATAATAATAATGTAATATACACTTCTGTTCGTCTTCCTGTTATTTTCAGTAGGGGTGTTTTTTTGTTGTTTGAGATGGAGTCTCCCTCTGTTGCCCAGGCTGGAGTGCAGCAGCACGATCTTGGCTCACTGCAACCTCCACCTCCTGGGTTCAAGGGATTCTTCTCCTGCCTCAGTCTCCCCAACTAGCTGGGACTACAGGCGCACCACCACGTCCAGCTGTTTTTTTTATTATTATTATTTTTAGTAGAGATGAGGTTTCACAATGTTGGTCAGGCTGGTCTTGAACTCTTCACCTCAGGTCATCCGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTAGAGGTGTGAGCCACCGCGCCCGGCCAGTTTTAGGTATTATATGCAGTACGGAACACCTTAGAACAGTCCCAGTACTATACCAAGCCAGAGGCTTGTTCCTCCAAATGTGGCCCTCAGACCATCAGCATTAAAATCCCTGAGATTTCCTTGTTAGAAATAAAGAATTTCAGGCCGGGCGTGGTGGCTGACACCTGTAATCCCAACACTTTGGGAGGCTGAGGTGGGCAGATCTTGAGGTCAGGAGATCAAGACCATCCTGGCTAACATAGTGAAACCCTGTCTCTACTAAAAAATACCAAAAAATTAGCTGGGTGTGGTGGCAGGCACCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGCATGAACCCGGGAGGTGGAGCTTGCAGTGAGCCCAGATCGCGCCACTGCACTCCAGCCTGAGCAACAGAGCGAGACTCCGTCTTAAAAAAAAAAAAAAAAAAGAATTTCAGACTCCACCCAGACCTACTGAACTAGAATCTGCATTTCAACAAGATCCCCAGGTGATTTGATTGCACATTAAAACTTGAAAGCTGTGACATACAGGAGTAGTAGACTCACTGCCATCCCTCTAAAATAGATCAGTAGTAAAGAGTTTGGAGAATCTACATTATTCTTTAGAAGGAAGAAATATGAAAAACTGGTTTTCGTTTTAGAGCTTAGGAGGAAAATGGGTACTTAGTACCATTATTAAACTCTGGGTAAGAAAATTTTGAAATAAATATGGTTATGAGATTAAGTTAGCTATAGACTATTAGGAAATTAAAAATAGAAAGGTACCATCATTTTCATAGGATTTACTTTTTCGTCCACTGTTTATCCTTCTAAACTCATCACTTATAACCTCAAATTTCAGTATAAATGGCCATAATAACAGAAATGCCAAGCTGCCATGGCTAATGCTAGGAATACAGAAGTCACTACTTGGATAAGTTAAAGGTTCTAAAATGTTCAGCTTACCAGCACTTAACACTTTTCTTAGTTTTTGTTGTTGTTGTTGTTTAGTCAAGGGTGGTAAACGCTTGGAAATACAATTTTATCCTTAGGTGGCTTTTGTTTTACAG
Seq C2 exon
AACTTCGATATGACCTGCCAGCATCATACAAGTTTCACAAAAAGAAATCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000138382:ENST00000260953:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF051759=MTS=PD(15.9=77.8)
A:
NA
C2:
PF051759=MTS=FE(12.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development