HsaINT0102237 @ hg19
Intron Retention
Gene
ENSG00000123600 | METTL8
Description
methyltransferase like 8 [Source:HGNC Symbol;Acc:25856]
Coordinates
chr2:172182552-172187208:-
Coord C1 exon
chr2:172187069-172187208
Coord A exon
chr2:172182659-172187068
Coord C2 exon
chr2:172182552-172182658
Length
4410 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAAT
5' ss Score
8.76
3' ss Seq
TTAATACTTTGTTTCCAAAGGAT
3' ss Score
8.15
Exon sequences
Seq C1 exon
TCACACTCGTCCTACAGAGCAACCCAGTGTTTTGCCTTTGTTCATGATGTATGTGATGATGGCTTACCTTACCCTTTTCCAGATGGGATCCTGGATGTCATTCTCCTTGTCTTTGTGCTCTCTTCTATTCATCCTGACAG
Seq A exon
GTAAATGAAGACGAAAGGGCAAAGTGGATGTGTAAAGCTCCTTTATCAGTAGTGGTTTTCAGAACTATCAAAGCAAAAATGACAATTTTTGAATTTATTATTTAGTGAGCAACATTATGTATAATACACAGCCTTTTAAAGGCAGTTTTTCCTTTCTTCGTACTTTTAGACAGAAACTGGTCAGACTACTTCATTAATGAGCTTTCTGTCACTGTCAGAATGAAGTGAGCATATTCTGGCAAGACACATACCTATTAAAAGTGACAGTGCTTCAAGGAAATTACAAATTCAGAACAACCTAATAGACTCCCAAGAGGGAAATTGTACTTGGTGATCAGAAACAAACATCTTTAGTGTAGTGTCTTCCTGAATGTTCATGAAGAGGTGGGCTTGGGATCTGTTTGGCTTCACACAGGCCTGTTGATGGGCTTTAAAAATTTTGTTCTAAAGAAGCACACTAGGGAATCAGGAGTTATTAAGATTTGCCAGATTATCCTTGGACCTTTATGATCTAAGGTTAGCCTGATGCCATCATTTAAATATTTATGACTTAGTTTCATACAGTGTTTTAAAACTATAAACATAGCTTTTCTCCAGAGAGAAAACATAAAGAGATATTACCAGCAATTAGAATGATTACCTTTCTTAAATCTTGCCATCTTCTATGTATTAAAGGGTACATATGGTAAGTACCAGGTCTGTGCTTTCATAAGGTTTCTTAAAATTGGGTTCTCACAGTTCCCTGGTGGAAGATACAGACTTGGCGTCAACCACTTTTTGTTTGATGAGTGTGACCCTTTTCCATAGAAACTGAGTTACCATGTGCTTATTTCTTTGCAATTAAAAGGCCACTAGGACCCTTTACAGTTCTTTTACTTCCCATTCAGAAATGAGCACTTTGATTACTTGTAGAAGAACAAATTCCATTTCCAAATAAATCTGAAATAAGATACTTTAGCACCTAGTGAGGTATGTCAGGTTTTATGAAGCTACTGTTTCCTCCCAGTTTCTATAACCTATTTCTTTCTGCTAATCTGTTTAGACTGTAGGCATTGTTCAGGTACTAATAGAAAGTTGTCATCTATGTGTTTGGTTTCCTTATATGAACAGTTAAAAGGATGGAGAGGTGGATAGAGAACAAGATTCCCCATTGACACCCATAACAAGAAACATCTAAATTCTACATATAACCACAAAAAGACTATTTGAAATTAGTTCAGATAATGTATTTTCTCATGATTTGAATTGAATGTTATAGAGAAGAGAAAGGCCAGGTGCAGTGGTTCACACCTGTAATCCCAGCACTTTGGGAAGCCGAGGTGGGTGGATCACCTGAGGTCAGGAGTTCCAGACCAGCCTGGTCAACATGGTGAAACCTCGTTTCTACTGTGAAACCTCTGCCTCCTGTAGCCAGGCATGGTGGTGGGCGCCTATAATCCCAGCTCCTTGGGAGGCTGAGGCAGGAGAGTCGTTTGAACTCAGGAGGCAGAGGTTGCAGTGTGCCGAGATTGCACCACTGCACTCCAGCCTGGGCGACAAAGCAAGACCTTGTCTCAAAAAAAAAATAAAAGGCTGGGCGCTGTGGCTCACGCCTATAATCCCAGCACTTTGGGATGCCAAGGCGGGTGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACCAAAAATACAAAATCACCTGGCTGTGGTGGCACACACCTGTAGTCCCAGCTACTTGGGAGGCTGAGACAGGAGAATTGCTTAAAACTGGAAGGCAGAGGCTGCAGTGTGTGGAGATCATGCCACTGCACTCCAGCCTGGGCAAGACAGAGACTCCGTCTCAAAAAAATAAATAAATGATAAAAATACAAAAATTAGCTGGGCGTGGTACTGCATGCCTGTAATCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATCACTGGAACCCAGGAGACGGAGGTTGCAGTGACCCAAGATCACGCCACTGTACTCTAGCCTGGGTGACAGTGAGTAAGACCCTGTCTCAAAAAAAGAAAAAACTAAAACCAAGGCAATGTCTATAGTGTCACTTAGGACTATAGTAGTAGATTCAACCCCAGAAAAGTTCTAGAAAAGTAGCATCTTGGTAGCTTGGAAAATTCAGGCATAAGCAAATGGCAAGCAATTTGGCTAGACCTTGAGTCTGGAGGACCCAGCTTAAATGGGAATAAATTGTAGGTGGCTACAAAAGAAGAGCGAATTGTCCTTCTTGTCACTGAAATGAAAATACAAAATATTACAGAGCCAAGCATAAAGCAGGCAGTCAATACATTTTTTATCTCTTCCTTCTCCTCTCCCTCTATCCAGAGATAAGTGAAGACAGCAGAGTTGGCCCAAGTAGGATGAAGAAAGAAAAGGGGCTTCATACCATTCCTGTCTTGTCCATCTCACCCCCAGCCCACTCCCACCTGCAGTTCTCAGGAATTGGCTCGGGAACTGCACTATGAACCAAGATGAGATGAGCAAGAAAAGTAGCTCCCGTTCCTTGCCTTTATCCTCAACCCCAGACATTAAAGGATAGCTGAGAGGAAAGAATTTGCAGGAGGAGGTGGCTACATTTTAAAGTGTTCGATTGTTTATTTTTCTGCATTTTAGTTTCATACTTGTTTTACTAATAATTACAGAAAGATTTTGCTATGTACGTAAAATATTTATATTGAAAGTGAATATTTTAAGGTTTAGATATGATTTTCTTTCATTCGCAAAGCCTATGATATAAGCACAGTATGAAAATAACCTGTAATAAAATAAACAAAAAATACGTTTCTTTTTTCTTTTATGTCCTTATGTGCTAGTTTTTTTAAAAGGACTTTTCACCTAATCATGCCACCTCCTTTTGTCCTACTTCTTTCTTGTTTTATAGTTGCTTTCATTTTCTCAGTATCTGCTTCCTTCATAACATGACATAATCTGAGTTTTACCTTACTATTCCACTGAACAGTGTTTTAATTGAAAGGAATTTACAGATTATCTGATTCAAACTTTTCATTTTTTTCAAATAAGAAAACCTCAGCAGCTTTAAGTAGCTTAGATAAGGCAGAGACAAGGACTTAGCACACAAGCTGCCATTTACCATTCTCTGCCCATGGCAGACATTGATAATCGATTTTGTACTCGGTAACTCGCAATGAGCTTTATGAGTCCTTCTCAGAGCTCTGTAGGCAGCCGATGCTGTCACTCAGAATTAATATGAGATCTGAAATCTATGCCATCCCTGGCCCATAATCACACATAAAGCCATGAACACTTAGCCAAAAACACTAAATCAAGAGCAGCTATAAGGGATTGTATTTGACTGGAAGCCAAATAAGTAGAATAAACAGTAAAGGAGAAAAGCAAAGGCTCCCTGCTGTTGAACTAGGGCTTGGAATGTGAATAAAATTTAAATAGGCAGACAGTAAGGAGGAGAGAATTCTTTGAGGAAAAACCATGTGAGCAAAGGCAGAGGCTGCTCAGGGCCAAGCATGACAGTTTGGCTAGGGGAGCTGCTTCAGATTGGAAAGCTGTTGGTAAGATTAATTGGGGTCAGTAGTAGGAGATCTTAAGAGCTCAACTAAGAAATTGAAATTTTATCCTATGGATTAAAATCATGAAAGTTTTTGAGCAAGGAGATGATTTGACAAAATTATCATTTTAAGCAGAATTATTCATCGATAACATGCAGGAAGGATTGACAGGGAGAATAATACAGCGTGTTAGGAAGCAGATTTGTTTCCAGGCCTAAGGAGATAGGGGTTGGTACTAAGGGAGTACAAATGGGAAACAAAAAAGACAGGAAATATCAAAGATGTCATTAAAAATAAAAATTAAAGAGGACATAGAATTTTATGGCCACATGGAGAGGACAGTGGAAGAAAAATAATTTCTCTTTCATGAGGTAAATGGTGGTACCTCCGAACTAAATAAAGAAAAGGAGAATGAGCTCGTTTTGGAGGAAAGATATTCCCTCTTTAGATATGTACAACTTGGGATGGCTTTGGCATATTTTTTATCTTGCAAGGAAAATGAAGCACACTCCATTGTTGTCTATCTCAGAACTACCTTAATTTTCTGTAAGTACCAGGAAACATCTGTGGTTTTGAAGTTTAGCTTTGACATCATACGTCAAGCTCTGTGAAGTTACCACTCTGATCATTTGGGTGATTTCTTGATACTCTAGGACTTTTGAATCTAGTCATTTAGCAAGTTGGTTTTGGTTTTTTCTTCTTTACAAAATATTTTTATTTTTGTTACCCTTATGTTTATGGTTTAGATTTCTTTGGCCTTATCAAGCTTTTCTTATTTTGTCTTCAACAAAGTTAAATCCAGCATATAAAACAAGATTTCTACAAACTGGGTATCTTTTTAATACTTTGTTTCCAAAG
Seq C2 exon
GATGCAAGGTGTTGTAAACCGACTGTCCAAGTTACTGAAACCTGGGGGAATGCTGTTATTTCGAGACTATGGAAGATATGATAAGACTCAGCTTCGTTTTAAAAAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000123600-METTL8:NM_024770:7
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF082427=Methyltransf_12=FE(43.8=100)
A:
NA
C2:
PF082427=Methyltransf_12=PD(17.1=48.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)