HsaINT0102299 @ hg19
Intron Retention
Gene
ENSG00000140545 | MFGE8
Description
milk fat globule-EGF factor 8 protein [Source:HGNC Symbol;Acc:7036]
Coordinates
chr15:89441914-89444966:-
Coord C1 exon
chr15:89444782-89444966
Coord A exon
chr15:89442764-89444781
Coord C2 exon
chr15:89441914-89442763
Length
2018 bp
Sequences
Splice sites
5' ss Seq
CAGGTGGGT
5' ss Score
8.56
3' ss Seq
GACACCCGCTCTGCCTCTAGATC
3' ss Score
9.96
Exon sequences
Seq C1 exon
GATGCGCCAATCCCCTGGGCCTGAAGAATAACAGCATCCCTGACAAGCAGATCACGGCCTCCAGCAGCTACAAGACCTGGGGCTTGCATCTCTTCAGCTGGAACCCCTCCTATGCACGGCTGGACAAGCAGGGCAACTTCAACGCCTGGGTTGCGGGGAGCTACGGTAACGATCAGTGGCTGCAG
Seq A exon
GTGGGTCAGCCTTCTTGGGATATGGGGCTGGGGTTGGGTGGGATGAGGTGGGACTGCCAGATCTTTGACCTCTCTCCAGCCCAGGCTTCTCTTCTGCTCCCCAAAAGAGTTCTGGAAAAGCCTTGTTTTTCTTCGGCTTTTCTTTCTTCTTCCCACCTGTACTCCCTTCTCTTGATCCTGCTTCCACCAAGGTGGAGAAAGGGTGTGTGTGTGTATGTGTGTGTGTGTGTGAATGTGTGTGTGTGAGTGTGTGAATGTGTGTGAATGTGAGTGTGTGTGAATGCGTGCGTGTGAATGCGTGCGTGTGAATGTGTGTGTGAATGTGTATGTGTGAATGTGTGTGTGTGAATGTGTGAATGTGTGTGTGAATGTGTGAGAATGTGTGTGAATGTGTGTGTGAGAATGTGTGTGTGAATGTGTGTGTGTGAATGTGTATGTGTGAATGTGTATTTGTGAATGTGTGTGAATGTGTATGTGAATGTGTATGTGAATGTGTATGTGTGAATGTGTGTGAATATGTGTGTGTGAGAATGTGTGTGTGTGTGTGAATGTGTGTGTGTGAATGTGTGTGTGTGAATGTGTGTGTATGTGTGTACACAAGGGGAGAGCCATTCCATGGGCTGCCACAGGATTGACAAGGCTCAGCCTATGGACAGACAGCAGGGCGGAGGCGGAAGAGGGAGACATGACCCAGGCATCTTGGGACCTCTCCCTTGAGCACAGCATACATATTCTCTGACTCAGTGTCTAAGAAGCCACCATGTGACAGCCCTTGTCTGTCATTGAAACTAGGAAACAAAAGAGAGCCATGGAAAACCGGAGCTTGTTTTATAGATGAGGAAGCCGAGAGCTGGCAGGACGATGATCTGCCTAGTACCCACCTGCTGGCTGGCAGTGAGTTGGGTTTACACCTGGATGTTGGGGAACTGTGTGTCCAGGTGCAGCTGGCAGGTTCTCCAGGGAGGTCAGGGACCGGGGACAGGAGGTCTGTCTCAGGGCCCCATGGAGCACACTGCGGAGCTGGGTTCCCTGAGGAGCTGCCTGCCTGTGGACACCCTCAGGACCAGTGTCAGACTGTGGGCGGCGCCGCAGGGAGCCTCTAGAGCAGTTCATGCCCCTCCAGGCTGTGGCCTCTCCTGTCCTTCTTCCCATCACAGTGCAGTGCAGGTCTCAGGCAGGGGTGGTTGGCGTGGAGTTGGCCAGGGCCCAGACCCTATGAGCTTTATAGCAGTGAGGTACCGAACACCATGTGTGGCAAAGTAGGTGGTATTATTTATGCCCCCTCACCGCTTTTTTTTTTTTTTTTTCTGAGACAGAGCCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCCATCTCGGCTCACCGCAACCTCCGCCTCCCAGGTTCAAGCGGTTCTTCTGACTCAGCCTCCCTAGTAGCTGGGATTACAGGCAGCCACCATCATGCCCAGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGTCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCTGCCTCAAGTCTCTCCCAAAGTGTTGGGATTATAGGCATGAGACACCATGTCCGGCCTTATGCCCATTTTATAGCCAAAGAAACTGAGGCTCACCCAAGTAGTTTTTTTCAAAACTAGAATTCATGCCTCAGTGTGTCTGCCTCTTTTCACCTTACTGGAGATGGTCCAAGCAGAGAAAATGTGGTTGGTTTCTTCTGTAGGTGGACCTGGGCTCCTCGAAGGAGGTGACAGGCATCATCACCCAGGGGGCCCGTAACTTTGGCTCTGTCCAGTTTGTGGCATCCTACAAGGTTGCCTACAGTAATGACAGTGCGAACTGGACTGAGTACCAGGACCCCAGGACTGGCAGCAGTAAGGTGGGTGTCTGTCCAGCTGCCCACCCTTTGCCATTCCTTCATTACTTCCCTGGGAGTCTGGCCTGGGGCTCTGAGGGGAGGGGGGCTGGCTCGGGGTCCTCCTGACACCCGCTCTGCCTCTAG
Seq C2 exon
ATCTTCCCTGGCAACTGGGACAACCACTCCCACAAGAAGAACTTGTTTGAGACGCCCATCCTGGCTCGCTATGTGCGCATCCTGCCTGTAGCCTGGCACAACCGCATCGCCCTGCGCCTGGAGCTGCTGGGCTGTTAGTGGCCACCTGCCACCCCCAGGTCTTCCTGCTTTCCATGGGCCCGCTGCCTCTTGGCTTCTCAGCCCCTTTAAATCACCATAGGGCTGGGGACTGGGGAAGGGGAGGGTGTTCAGAGGCAGCACCACCACACAGTCACCCCTCCCTCCCTCTTTCCCACCCTCCACCTCTCACGGGCCCTGCCCCAGCCCCTAAGCCCCGTCCCCTAACCCCCAGTCCTCACTGTCCTGTTTTCTTAGGCACTGAGGGATCTGAGTAGGTCTGGGATGGACAGGAAAGGGCAAAGTAGGGCGTGTGGTTTCCCTGCCCCTGTCCGGACCGCCGATCCCAGGTGCGTGTGTCTCTGTCTCTCCTAGCCCCTCTCTCACACATCACATTCCCATGGTGGCCTCAAGAAAGGCCCGGAAGCGCCAGGCTGGAGATAACAGCCTCTTGCCCGTCGGCCCTGCGTCGGCCCTGGGGTACCATGTGGCCACAACTGCTGTGGCCCCCTGTCCCCAAGACACTTCCCCTTGTCTCCCTGGTTGCCTCTCTTGCCCCTTGTCCTGAAGCCCAGCGACACAGAAGGGGGTGGGGCGGGTCTATGGGGAGAAAGGGAGCGAGGTCAGAGGAGGGCATGGGTTGGCAGGGTGGGCGTTTGGGGCCCTCTATGCTGGCTTTTCACCCCAGAGGACACAGGCAGCTTCCAAAATATATTTATCTTCTTCACGGGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000140545-MFGE8:NM_001114614:6
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.057
Domain overlap (PFAM):
C1:
PF0075420=F5_F8_type_C=PU(32.1=72.6)
A:
NA
C2:
PF0075420=F5_F8_type_C=PD(0.1=0.0),PF0075420=F5_F8_type_C=WD(100=89.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)