HsaINT0103674 @ hg38
Intron Retention
Gene
ENSG00000078403 | MLLT10
Description
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 [Source:HGNC Symbol;Acc:HGNC:16063]
Coordinates
chr10:21730900-21733087:+
Coord C1 exon
chr10:21730900-21731054
Coord A exon
chr10:21731055-21732898
Coord C2 exon
chr10:21732899-21733087
Length
1844 bp
Sequences
Splice sites
5' ss Seq
ACAGTAAGT
5' ss Score
9.49
3' ss Seq
ACTATCCAAATGTGTGGTAGTTT
3' ss Score
3.86
Exon sequences
Seq C1 exon
ATCCCCTGTAAGCAGCTTACAGATTCGCTATGATCAACCAGGCAACAGCAGTTTGGAAAATCTGCCTCCAGTAGCAGCCAGCATAGAACAGCTTTTGGAGAGGCAGTGGAGTGAAGGACAGCAATTTTTACTAGAACAGGGTACTCCTAGTGACA
Seq A exon
GTAAGTATTCATTTTCTTATATGTGAATCAAGACAGATGGGCAGATGGACAAACAGGCAGATGGATGCAGAAGTCACTTTTCATCCAGAGTAGTAATGGGATTATGATATACATTTTATATAATACAGTGAGAGAAAGTATAAGGTGAAGTGGTTTAATAGAAGAGATTCTATAGTGTTACTGCTTGGACTTGAATCCTGTCTTTACCTGTTATTAATAGTATGATCTTGGGCATGTTTTTTAAAGTTCTTTAATCTCCTATTTTTACAATTGGGAGTAATAATGCACCCATATCAGAGGGTTATTGTGAGGATTAAATGACATGAAAAATGTAAGGACCACTGCCTGGCTCATACATAGCATTGTCTCGGTGCTTACCATGATTATACATATTGGTACTTTGTGTCTCCACTGTACTTTGTTCTTATCAATCAGTTTACTAAAATACATGAGCACTGTCTTCTCTTACCCCAATTGTTAGAAGAAAACTTGCTCACCTCTGGAAAACTTACTTTAAAAAATACAAATAGTCAAGTATGGCCGGCTAGCTTCTTCATTTTATAATTTGGAGGAAGAATAATAATTATTGAATTAAATCTATAATTAGTATATATTATGCTTATCATCTATTGGATTATAGAGCATGTACTATATATCTGTGTTTCAGTATCTTCACCATTTCAAGTATTAGGGCCGTGGGTGTAAAATGCAGAGTTAAAATAGGTGGTGGTTAGCTGGAGATGTGGCCTTGTCTTAATTTTAGGGAAAAATAGGTGGTTTTCATCATTTTCGAGTATAAACTTTTGCTGCCTCATTTTATTGAAACATTTTGCTTATTGTTGGCTAGCTAAGTGCCATAAATTGGTATTTTATGAATGGTACCCTGACAAAAAATGCTAATTAATTGTGAGGAAATTCATGCCAGGCTAATCCTTTAAACACGATAGCTGGAGGATAGGTTTAGCTGAGTCTTATTGCATCTCATTTGGGCCCACTAAGGTTTCTTTGTGGGATCTTGGAGGGGAGGGATAAAAGTTAAATCCATGGGAAACGGCCAGATGTGTCTGTACCAGAGGAGTTGTATCTTCTAAAGGCCCTGAGGTCATGTTAAACAAATACAACTTTTTAGTATGTGACGGACACTTCAAAAATCTTAACGGCAACACTCTGTGTTGTTAGCTGGGAGGTCCAAGTTGTGGAAGGAATTGAAGTACTTGAGGTGATGGGGCCAGACTGAAAGTCAGCCTGTTTACAGGGGATGCGCCTTTCTCCAGGACTGGAGAGGTGGCTGGGCGCACACATAGCGCTCCCTGCTGGGTGACCTGCAGAGCAACATGCTGAGCAGCTGGGATTAGGGGCTTCCTGCCAGGCGTCTGATGGCAGCACTTCGTTTAAACCGGACAACAAACAAAAACATGTGCTCATTATTTTGGTAGAGGGTATTGGTGCGATCCTTAACCATTCTGTATATGACTTCAATGCAAAATAGTGACAGGCACTTGAATTTTTAATAGGCTTTTATTTTGATGAAAATAAAATGTCATTACTTTTCATTGAGAATGGAAAATTACCTGAAGCTGGTGTGTGTTTTTTGGTATGTGGCAACAAAGTTTCCAGAAGGTACATCCAGGAACACTTTGCCTTTGTGCTTATAAAAATACAAACATAGATAGGCAATTTATATCCATAAACAAATTTAGGAACAAAACTTTATCATTTAGAAACACTTTACAGAATTTCTACTGTTCTATTTTAACTTATTTCTAAGGTTACCGGCACTGCGTAAAATACTTAGTCTTATGTGTGTACTTGTCATTATTAAAAACTATCCAAATGTGTGGTAG
Seq C2 exon
TTTTAGGAATGCTGAAGTCATTACACCAACTTCAAGTTGAAAACCGAAGATTAGAGGAACAAATTAAAAACTTGACTGCCAAAAAGGAACGGCTTCAGTTATTGAATGCACAGCTTTCAGTGCCTTTTCCAACAATAACAGCAAATCCTAGTCCGTCTCATCAAATACACACATTTTCAGCACAGACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078403:ENST00000377072:18
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.701 A=NA C2=0.656
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCAGCTTACAGATTCGCTATGA
R:
CAGTCTGTGCTGAAAATGTGTGT
Band lengths:
334-2178
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development