HsaINT0103675 @ hg19
Intron Retention
Gene
ENSG00000078403 | MLLT10
Description
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 [Source:HGNC Symbol;Acc:16063]
Coordinates
chr10:22021828-22022521:+
Coord C1 exon
chr10:22021828-22022016
Coord A exon
chr10:22022017-22022432
Coord C2 exon
chr10:22022433-22022521
Length
416 bp
Sequences
Splice sites
5' ss Seq
CTGGTAAGT
5' ss Score
10.65
3' ss Seq
TTTGTCTTTTATTATTCTAGCTC
3' ss Score
9.05
Exon sequences
Seq C1 exon
TTTTAGGAATGCTGAAGTCATTACACCAACTTCAAGTTGAAAACCGAAGATTAGAGGAACAAATTAAAAACTTGACTGCCAAAAAGGAACGGCTTCAGTTATTGAATGCACAGCTTTCAGTGCCTTTTCCAACAATAACAGCAAATCCTAGTCCGTCTCATCAAATACACACATTTTCAGCACAGACTG
Seq A exon
GTAAGTGTGAAAATATTTATTTTGTATCTAAGGAAAATAGGCTTTCAGTTTTATTTGTATTATAAGTGAGTAATAATTGGTCACCAGTTATATGAAGATGTAGAAAAGGAACTATAGGTTGTTTTTGAAGGGCATAAAGAATCCTGTTAAGTGATCAACTTGAATTTAACTTTCTTAGTCCATAATATAATGGTAAAATTTACTTAAATGTCTAATGATCTCGTTATTGATTTAAAGCGATGGTATTCAATATAGATTTTTTTTTCTTATTTAAATCAGTCTTAGGAATAGCAAGACTAGATATTTAAGTGGTTTTGATACGGGCTTCAGCATAAGCTTTTTAATAAGCCTTTAATCTTACACATAATGTAATTTAATAGGGTAAATAGGTTTCTTTTTGTCTTTTATTATTCTAG
Seq C2 exon
CTCCTACTACTGATTCCTTGAACAGCAGTAAGAGCCCTCATATAGGAAACAGCTTTTTACCTGATAATTCTCTTCCTGTATTAAATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078403-MLLT10:NM_004641:19
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.656 A=NA C2=0.933
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGAATGCTGAAGTCATTACACCA
R:
AGGAAGAGAATTATCAGGTAAAAAGC
Band lengths:
262-678
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)