HsaINT0103741 @ hg19
Intron Retention
Gene
ENSG00000108292 | MLLT6
Description
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 [Source:HGNC Symbol;Acc:7138]
Coordinates
chr17:36868100-36869042:+
Coord C1 exon
chr17:36868100-36868267
Coord A exon
chr17:36868268-36868943
Coord C2 exon
chr17:36868944-36869042
Length
676 bp
Sequences
Splice sites
5' ss Seq
AAGGTAGAA
5' ss Score
6.33
3' ss Seq
AGTCACCTCTCCCTCTCCAGAGT
3' ss Score
8.17
Exon sequences
Seq C1 exon
AAGACATCCCGGCACAGCAGCGGGGGAGGCGGAGGAGGCGCTGGAGGAGGAGGTGGCAGCATGGGGGGAGGTGGCAGTGGTTTCATCTCTGGGAGGAGAAGCCGGTCAGCCTCACCATCCACGCAGCAGGAGAAGCACCCCACCCACCACGAGAGGGGCCAGAAGAAG
Seq A exon
GTAGAAGTCCTCCCCCACCTGCCATCACTCCCACACGGGGACTTGGAGACTCACAAACATGGCTCAAAAAGCCATCATGAGGTGCCCTTAAGGTCTTGGCCCTGCCTTCTTCCTTCCTCTGAGGCCACTGAGGGCAGGAGGGGGCTGAAATGAAACGGTGGGGGGGTGAGGCGGGAGCTTGGCTTCCCTGTGGCTGTGTTAGTGGTTCCTCTGGGTCCTCCCCATGACATCACAGTGTCCCCCAGGCCCCAGACACATGGCTCTGCACGTTGCACACGTCTCCGCAGTCCAGCCATGTGCCGCCTAGTAAGTGCTCATGCCTGCATTCCCTCGCGCCACATAGCACAGCGTGCCCAGCTCCTGTCCCTCTGTGCAGCTGTGTCCCAGGTGGACACCCTTGCAGGTGTTATGTTCACGCGCGTGGTGCTCTATAGCACTGGCGTGATAATGGGACAGGCTATTTTTAGCAGGCGGGGCCGGGGGAAGGGCTGTTGGCTCTCATAGGAACTTGCCTGAATCGCTCCTGCCCAGCCCATTATCCAGCCCTCCTCAGGGAGAGATGGTGCCCACAAAACCCCATCCCTAAGGGGGTGTCAGCTCCCCATACCCACATGTCATGTTTGTCCTCGCCCAGACAGCCCCCCAGCACAATATCTAGTCACCTCTCCCTCTCCAG
Seq C2 exon
AGTCGAAAGGACAAAGAACGCCTTAAGCAGAAGCACAAGAAGCGGCCTGAGTCGCCCCCCAGCATCCTCACCCCGCCCGTGGTCCCCACTGCTGACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000108292-MLLT6:NM_005937:7
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.946 A=NA C2=1.000
Domain overlap (PFAM):
C1:
PF128102=Gly_rich=FE(44.7=100)
A:
NA
C2:
PF128102=Gly_rich=FE(26.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGACATCCCGGCACAGCAG
R:
CTTGTCAGCAGTGGGGAC
Band lengths:
267-943
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)