HsaINT0107439 @ hg38
Intron Retention
Gene
ENSG00000109061 | MYH1
Description
myosin heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:7567]
Coordinates
chr17:10498974-10500752:-
Coord C1 exon
chr17:10500626-10500752
Coord A exon
chr17:10499093-10500625
Coord C2 exon
chr17:10498974-10499092
Length
1533 bp
Sequences
Splice sites
5' ss Seq
CAGGTGGGC
5' ss Score
8.07
3' ss Seq
CTGGACTTGGTCTTTTACAGGTG
3' ss Score
9.46
Exon sequences
Seq C1 exon
GGAAACCTTGAAAAGATGTGCCGCGCTCTAGAAGATCAACTGAGTGAAATTAAGACCAAGGAAGAGGAGCAGCAGCGGCTGATCAATGACCTCACAGCACAGAGAGCGCGCCTGCAAACAGAATCAG
Seq A exon
GTGGGCCATGTACCAGTACTGACCTTGAATGACAAATTCACCCTGCATGTGTAATCCACTGAAAAACTCTGCATTTATTTACTTGAGGTCATATACTACCTCCCTGGGAGATCCCCACTAATATGAACACATTATTGACCACTGGCATGAGGTTGCTTTCTTTCATATATATACGAGAGAAATATATGTGTATATATATGAAACATATATATCCATATATATATTTGTATATATATCCATACATACATATATATATATATATAAAGAGAGAGAGAGAGATAAATAGAATCAGGCCCTTCTATTTTTGAAGACTTTAAGGGAGACTTGGCTTTAATCAAAAAGTTATCAAAAACAAAGTGCATCCTTACAGTACCTCTTTTCACTTTTCAAAATGCTTTCGCAAGCTATGTGTTACTTTATTTTCCTCATTAGTCTGTGTAATACTATCCCCATTTTAAAGACAGTGGATTATGGTAGTGATGAAGCAACTTGTCCAAGAATGTTTACTCCAGTCTTTTTCCTGAAGTCTTGCCAATTACTGGTAACTAACACGGTTAAGTAGGGAAATATTCAAGACCACAACCCAGCTGAGAAGCATTCAAGTAAGATTTGTAGATTTTTGATTAGAGAAATTGGAAAGTCTCTGCATTTATTCCCCCTCCTACTGACGTGTCCAACTTTCTACCAGAGTTGTATCTCCCCAGGTAGAGGTAACAAAATGGAAATTGTTTTATGGGTAATTTAGGCTATTAAAGTAATAGGCAGGTTAAAGTGTTGGAAAATCACTCTACACTTTTGGTATTCAAATACTATTCTTTCTATAACAAAGTTCAGAATAAATATTTATTATAATTCTTATTAAATGCCAGAGATAAAGTTCAAGATAACTAGTATAAAAATGGTGTGGAAAAGTTTTACTATCTTTCTAACATAATGTAGTGCATTTTCTGCATTATGGTGCTTAAAAAATTGAAGACATGTGTAAATGCCATTTAGTTTGGAAAGTACTTATCCAGAAACCAATTCATTCTGGGGATGGGAGACCACTTAATCATTTCTTAATATAAAAATCTTTCCAGAATTTCTCTTGACTATCATTTCTACTTACAGAAGACATTGCCCAAAGTCTCTTATTTTCCACAGTATAAATCCTTTGTTTCAACCAACTTTCAATGGAAGGCAAATTAGACAACACTACTGCCTTACATAAAATAAAAAGTACTAGAATATTTTGTTGGCTTGATTTACATTTTTTTCATGTTTCTTCATCAATTTTGACTACGATCAAATAATCGTAAATATCTCTTGAAATCTTTTGTGCTGTTCACAAGCATGTAATCTGCCTCAAATTTCTCCATGCTTCTAATTTTTACATGGATCTGCTTATCAAGGTTAAAGCGGATGTTGGTGGTTTGTTGTCACCCATGCCCTCCATCAAGTTTCAAACTTGGCTCCCTTTCCCTGCTCAAGTTTTTATTTTAGAGTTTTAATTTCCAAAGTAAGGTTGAGTTTTCTGGACTTGGTCTTTTACAG
Seq C2 exon
GTGAATATTCACGCCAGCTAGATGAAAAGGACACACTAGTTTCACAGCTCTCGAGGGGCAAACAAGCCTTTACACAACAGATTGAGGAACTGAAAAGGCAACTTGAAGAGGAGATAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109061:ENST00000226207:28
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.767 A=NA C2=0.325
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(4.9=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(4.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGAAACCTTGAAAAGATGTGCCG
R:
CTTTATCTCCTCTTCAAGTTGCCT
Band lengths:
246-1779
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development