HsaINT0107482 @ hg19
Intron Retention
Gene
ENSG00000133026 | MYH10
Description
myosin, heavy chain 10, non-muscle [Source:HGNC Symbol;Acc:7568]
Coordinates
chr17:8395615-8396342:-
Coord C1 exon
chr17:8396094-8396342
Coord A exon
chr17:8395828-8396093
Coord C2 exon
chr17:8395615-8395827
Length
266 bp
Sequences
Splice sites
5' ss Seq
CAGGTGGGT
5' ss Score
8.56
3' ss Seq
CCCCATCCCCTTCTGCACAGCTG
3' ss Score
7.28
Exon sequences
Seq C1 exon
TTGGCTGATACCAAGAAGAAAGTAGATGACGACCTGGGAACAATTGAAAGTCTGGAAGAAGCCAAGAAGAAGCTTCTGAAGGACGCGGAGGCCCTGAGCCAGCGCCTGGAGGAGAAGGCACTGGCGTATGACAAACTGGAGAAGACCAAGAACCGCCTGCAGCAGGAGCTGGACGACCTCACGGTGGACCTGGACCACCAGCGCCAGGTCGCCTCCAACTTGGAGAAGAAGCAGAAGAAGTTTGACCAG
Seq A exon
GTGGGTCGGCCACGTGTCGTTTCCTCCTGGCAGAGCTCTTGCTTTTGTTCGTTTGGTTTAAAATAATCTTATTTAAAGGCATTTAAATGTGATACATGTTTATATCAAAATTGGAAAAAGGGAAAGCAAAAAAAAAAAAAAAAAGGAAATACAAGAACACCATAATCTAGTGGCAGCACTCTAGCGATAAATCAGCCACATGGTGGAAGAGAAAAGTTGATGTCACTGTTTCGGTTTTTCGTATTCCCCCATCCCCTTCTGCACAG
Seq C2 exon
CTGTTAGCAGAAGAGAAGAGCATCTCTGCTCGCTATGCCGAAGAGCGGGACCGGGCCGAAGCCGAGGCCAGAGAGAAAGAAACCAAAGCCCTGTCACTGGCCCGGGCCCTCGAGGAAGCCCTGGAGGCCAAGGAGGAGTTTGAGAGGCAGAACAAGCAGCTCCGAGCAGACATGGAAGACCTCATGAGCTCCAAAGATGATGTGGGAAAAAAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133026-MYH10:NM_005964:31
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.386 A=NA C2=0.761
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(9.6=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(8.2=100),PF115593=ADIP=PU(36.9=57.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGGCACTGGCGTATGACAA
R:
GCTGCTTGTTCTGCCTCTCAA
Band lengths:
296-562
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)