HsaINT0107514 @ hg38
Intron Retention
Gene
ENSG00000133392 | MYH11
Description
myosin heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:7569]
Coordinates
chr16:15738565-15740188:-
Coord C1 exon
chr16:15740051-15740188
Coord A exon
chr16:15738689-15740050
Coord C2 exon
chr16:15738565-15738688
Length
1362 bp
Sequences
Splice sites
5' ss Seq
AAAGTGAGT
5' ss Score
8.4
3' ss Seq
CTTTCTCTTTCCCCAAAAAGGAA
3' ss Score
8.6
Exon sequences
Seq C1 exon
GACCTTGAAGAACAGCTGGAGGAGGAGGAAGCTGCCAGGCAGAAGCTGCAACTTGAGAAGGTCACGGCTGAGGCCAAGATCAAGAAACTGGAGGATGAGATCCTGGTCATGGATGATCAGAACAATAAACTATCAAAA
Seq A exon
GTGAGTAGGGGCCGGGTGCAGTGGCTCACGCCTATAATCCGAGCACTTTGGGAGGCCAAGGTATGTGGATCACTTGAGGCCAGGAGTTTGAGACTAGCCTGGCCAACAGGGTAAAACTCCATCTCTACTAAAAATACAAAGATTAGCCAGGTGTGGTGGCCAGTGTCTGTAATCCCAGCCACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGTAGAGGTTGCAGTGAGCTGAGATCGTGCCACTGCACTGCAGCCTGGGTGACAGAGTGACTCTGTTTCAAAAAAAAAAAAAAGTGGAATCAAGTTTCTGCATTAAAAACAACAGGCTTACCAGGATCAGGGAGATTTTGGGGATTTGGGACTTTCAGTTCTCAAAGCAGAAAAGCCCTTAGAAAACCAGGACAAGCTGGTCACCGTAGTCAGTAGTCACTAACCAGCCCCACCTGCTTTTAGTTCTTTGAGCTGGATGTCAGCTTGGCCCCTACTGTGAGCCAGGCTCTGTGTTAGATGCAGGTATGCATGGTGAAGGAGGACCCTTCCCTTGTGGGGTTTATACTGTAGTGAGATGGCAAATAATCGTCATTTACCATGGTGATCAGGGCTCTGAAGGAAACGTTCACCATATTTTAAGAGTGCGGCAGGCCGGGTGCGGTGGCTCATGCCTGCAATCCCAGCACTTTGGGAGGCTGAGGCAAGTGGATTACCTGAGGTCAGGAGTTGGAGACCAGCCTGGCCAACACGGTAAAACCCCATCTCTACTAAAAATACAAAAAATTAGTTGGGTGTGTTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAACGTGGGAGGCAGAGGTTGCAGTGAGCTGAGATAGCAACACTGCACTCCACCCTGGGCGACAGAGTGAGACTCTGTCTCAAAAAAAAAAAAAGAATACAGCAGTGGGGGATAGAGGAAGGGTATTCATAGAAGACTTCCTGGAGGAGGTGACATTTAAGCAGAAACTTAAAGATGAAGGAGCAGTTAGAGGGGAGTAGAAGAGCATCTCAGCTGGTTGGCCCACTGTGCAAAGGCCCTGGGGCAGGGAAGAGCTGGCCAGTGGCAGGAATGGAAGGAGGGTACCTTTAGCTGACCATACAATATGAGGGACAAACTGGCACGAGATGAGAAATGGCCAGTTTTTGGAAATTGTTATGGGACTTCTCTTTACCATTTAAAACTCTAGTTGTATTTTGTTATAATGTGGGTTTTTCTTTCAACTGTTTACATGGAAATCACTAAAAGTGAAACATAGATTCTAGAGAAAAGAAAAATCCTAAAGCTATCTCTTTCTCTTTCCCCAAAAAG
Seq C2 exon
GAACGAAAACTCCTTGAGGAGAGGATTAGTGACTTAACGACAAATCTTGCAGAAGAGGAAGAAAAGGCCAAGAATCTTACCAAGCTGAAAAACAAGCATGAATCTATGATTTCAGAACTGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133392:ENST00000300036:23
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.457 A=NA C2=0.786
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(30.6=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(27.9=100),PF0003816=Filament=PU(1.9=11.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACCTTGAAGAACAGCTGGAGG
R:
CTTCCAGTTCTGAAATCATAGATTCA
Band lengths:
262-1624
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development