HsaINT0107520 @ hg38
Intron Retention
Gene
ENSG00000133392 | MYH11
Description
myosin heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:7569]
Coordinates
chr16:15724647-15724992:-
Coord C1 exon
chr16:15724888-15724992
Coord A exon
chr16:15724800-15724887
Coord C2 exon
chr16:15724647-15724799
Length
88 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
3' ss Seq
TCTTTGCATCCCTTTTGCAGGAG
3' ss Score
10.2
Exon sequences
Seq C1 exon
AATGAAGTTGAGAGCGTCACAGGGATGCTTAACGAGGCCGAGGGGAAGGCCATTAAGCTGGCCAAGGACGTGGCGTCCCTCAGTTCCCAGCTCCAGGACACCCAG
Seq A exon
GTGAGTGTCCTGCCACATCATCCAGGGGACCTGGGGGGTGGCCTTCCTCGGGGCAGGTCCCTGGGACCTCTTTGCATCCCTTTTGCAG
Seq C2 exon
GAGCTGCTTCAAGAAGAAACCCGGCAGAAGCTCAACGTGTCTACGAAGCTGCGCCAGCTGGAGGAGGAGCGGAACAGCCTGCAAGACCAGCTGGACGAGGAGATGGAGGCCAAGCAGAACCTGGAGCGCCACATCTCCACTCTCAACATCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133392:ENST00000300036:29
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.457 A=NA C2=0.824
Domain overlap (PFAM):
C1:
PF0003816=Filament=PD(1.9=14.3),PF0157614=Myosin_tail_1=FE(4.0=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(5.8=100),PF041569=IncA=PU(39.5=88.2),PF045827=Reo_sigmaC=PU(31.9=86.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATTAAGCTGGCCAAGGACGTG
R:
GTTCTGCTTGGCCTCCATCTC
Band lengths:
174-262
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development