HsaINT0107638 @ hg19
Intron Retention
Gene
ENSG00000144821 | MYH15
Description
myosin, heavy chain 15 [Source:HGNC Symbol;Acc:31073]
Coordinates
chr3:108172853-108174706:-
Coord C1 exon
chr3:108174583-108174706
Coord A exon
chr3:108172990-108174582
Coord C2 exon
chr3:108172853-108172989
Length
1593 bp
Sequences
Splice sites
5' ss Seq
AAGGTAACC
5' ss Score
9.24
3' ss Seq
ACATCTGACTTTTCCTTTAGGTG
3' ss Score
11.41
Exon sequences
Seq C1 exon
GTACTGCATTCTGAATCCAAGGACCTTTCCAAAGAGCAAGTTTGTGAGCAGCAGAAAAGCAGCTGAAGAATTACTTGGCTCCTTGGAGATAGACCATACCCAGTACCGATTTGGAATCACTAAG
Seq A exon
GTAACCAGAAAACTGCAAAGAATGCATTTGGAGACGAATGGGGGGAAGACTGTGTATCTTAAAATACCTGTGAATGCTCAATTATAAGGCATTCTTCAGCTCTCATGACCATAAATATCACAAACAGATCTTAGCTGAAGGTGAAAACTTCGGTGCTGTTTGAGAAAAATATTCAATGTTTTTTAAACCTCAGTTTTGACTACATTTACATTTTTATAATTAGTCAACTAAGCAAATTTGTGTCAAGATATAAAATACTGAATCAACCTGATGTTATGAGAAAATGTGTATATATCAGAGCTAGAAAAAGTGAATCAGCTTCCTGGAGCTAATGGCTTGTCTGTGTGTGAACTGATTCATCCACCATATTCTTTCAGGGACAGTATTCTCTTAGGGACTAATTTTTCTGAGTAATTTAAAACTTTAAAGTTAACCCACTATCAAAAAATTAATCCAAAACCAACTTCCTTAAATGTGATTCCCTAAATTCTACTTCATCTTAGATGATATTGGCATGACTCACATATTTTGGGAAACTTCTAACTTATCAATAGATTTGGTGTTATCTGGCAGTCAACATCAGTTTGTTCCTAATGACATTCATATAAGGAACAAATTATTTGAAGGAGAGTTAAAAAATTCAGGATAAAGACCTCATAGAATTAGAACTCTGTAGGATATGGTTATAAAATGTTGACTCCCATATTTTGAGTACCTGAGAATCAGTTTCTGCTGTTTATTGTTTCTGCTGATTTTCACTGATGATGCCTTCCTTCCTTGTGTGTTTAGTTATTTTTACTGTATACTATTCATCTGGGCCAAGATTGACCTGAGGCAAGTGAAACTCCTAAGGCACAAATTTCAAAGAGGCTCTCATTCTCAGGGTTGGGCAAGTGAGGTTGAAAGGCACACACTCTCAGGGCACTCTCACACTTAGTGCCTCCATAAAATGTGTGCTTTAGGCACCTCACTCATTTCACCTTGTTTGTTAGTAATCATTCTTGAAAAAATACTTTTGTGGATTATTTGATGCCTAGACAAAAGTGCCTTACTCTAGAACAGAGGTCAGCAAACTATGGCCCAAGAGCCATGTCCATGGACTGTTTTTTTAATATATGGCCCACTAGCTAAAAATGGTTTTAGATGGTTCACGAATTGTTTAAAAAAACAAGAATATCCTACAGAGATTGTGTATAGCCCATAAAGCCTAAAAATATTTACTATCTGATCCTTCACAGAAAATGTTTGCAGAACCCTACCTGGTACTTTGGCACACTGCATGCCTGAGCCCATCTTAAAACTTAAACCAGGTTCCCTAAACAATTGAGACATTATTAATAGATAAGGGGAAGAATAGTTTAAGTTCTTAGGCAAACAATAGAACCACATGATTTAATAACGTTTTTTTTTTCACATTTTAGATTTATAAAATCAAACTTTCTAAGAAGTAGATTTTACACATTAAATAAAACTTACAAGAAATGGAATTGATACAGTTATCCCTAGGAACACAACAGTTGCTCACAGGATCATTTAATAAACATTTGCTGAATACCCATTATCAGTGGAGCTAACATCTGACTTTTCCTTTAG
Seq C2 exon
GTGTTTTTTAAAGCTGGGTTTCTGGGCCAACTGGAAGCAATAAGAGATGAGAGACTATCTAAAGTCTTCACATTGTTCCAAGCCAGAGCACAGGGCAAACTGATGCGAATCAAATTCCAGAAGATTCTGGAAGAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000144821-MYH15:NM_014981:21
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(6.1=100)
A:
NA
C2:
PF0006316=Myosin_head=PD(0.4=6.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTGCATTCTGAATCCAAGGACC
R:
TCTTCTGGAATTTGATTCGCATCA
Band lengths:
246-1839
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)