HsaINT0107644 @ hg19
Intron Retention
Gene
ENSG00000144821 | MYH15
Description
myosin, heavy chain 15 [Source:HGNC Symbol;Acc:31073]
Coordinates
chr3:108147339-108149769:-
Coord C1 exon
chr3:108149679-108149769
Coord A exon
chr3:108147729-108149678
Coord C2 exon
chr3:108147339-108147728
Length
1950 bp
Sequences
Splice sites
5' ss Seq
CAGGTAATC
5' ss Score
6.99
3' ss Seq
AAAATTATTTCTTGCTACAGACT
3' ss Score
5.51
Exon sequences
Seq C1 exon
AAAAGAATTAGAATTGAGTCAGATGAATTCAAAAGTGGAGAATGAGAAAGGCCTGGTAGCTCAGCTTCAGAAGACGGTTAAAGAGCTTCAG
Seq A exon
GTAATCAATTATCAAATATGCCTGTGTATTTATATTTAGATCCATGGGTGATGACTGGTGGTTCAATGACTAATTCTCTGCCAAGGTATTCATACCCTTAGCCAACCACAGGCAGAGGCAGAAAAGAACAGTGGTTAAGAAGGGAAACTGTGGCATTCCACAGATAGAGTTAAGCTTAAATTTCCTTATGAGAATAATAAAAATGAATAGCTAATTGGTTGACTGTTTGCTGTGAACCAGGCATTGTGCTAAAATCCAAAACTTGTTTTTTCACTCATGAATCCTTCTGGCAACGATTGAGCTCATATTACTAAATGCAACAATATATTTAAGTAGTAAGCACAGTGCCTGACCCATGGTATGCATTCAGTGTTAGCAATTTAATTTTTATGATGATTATTCTTTGTGATTAGAAGGCGATTGAAAATCAGTAAGTTCTATAGGTACTTGTGGCCTCAAAACATTATTTGATAATGGATAGCTATTTATAAGTTTTAGACCATGTGAGTTTTATAGCATATGACCATGTTGTAAAGTAATTTTACACACAATTGCACACATACACATTTAGATGGATAATTTCCCTTTGAAGCTAAATAAATATCTTAGTAATATAACCATGACTCAAAATAATTTTGGAACATCTTTCTGATATTTATCTTCTGAGATATTTTGAGCCAAATAAGAAAACCAGTCTCAATGTTTTGTAAACATTTTAGTTTCAGACACACTATTAATCTCCAAGTGGTTATCATATTCATTGGGCTTGTCTTCAAATGACTCTTGACTTTATCCAAAATAAAGTAAAAAAACACAAACTTTTCTATATATCCAAAAGACAAATTTCCTTACCTTGATGACTCAAAAAGTTCTCTAAAGATTATTTCTGACAAAACATTTCAGAAATGTTTGGTTCAATGGTGGTATTATTTGGGATAAATATTTTCTTGGATCCCATGATAACCAGTTGGAAGAGGATCATGGTTACTTGAATGTGGAAATCATACTTTCTTTAAGCACCTTTTCTGTCATACCTCATCTATAGAACTGATAGACTACTTATTTGATATAATCTAGAAATTAGTTTTTTCTAAGCCACAGTAGTCTTATTTAATGGAAAGGAAAACATATTCTAAAACAGTTTCTATCTTGTTTTCTCCCCTATCCTAATCTATGCCTAATTACTTAAGGTGATGATAATAACATCAGTGGCTTCATTGTACTGTAATACAGTAATGTTCTCAGGATTTGTAGACCTGTTTGGCCTATACTAAAAGGGCTTGGGGCTCTGAGAGTTGTTATCACCTTTTTTTTCCAATAATCCTGCCTCTGATGATACTGTATCTCTACTCGCTTTAGTAGTCCACATTCCTTCACCAGCTCTCGTTTGTTATTTCAAATCTCTTCCTTGAAATCTCCTGCAGACTAGAAAACCAAGTAACCAAGTTTTTTAGAATTGTGTGTAAAATTAAATTGATGCTATTTCTTACAATTAAATTGCTTGAACTTGAAGATGTTCATTTTATTGATCAGATTTTTGCCCAAGTCCTAGATAGTTGAGATCAGATAAACGAATTTCAAATGAGGAAGATTTTTGTATATAAAATTTACCATTCCAATTTTTATAAATGCTCTTAAACAGTTTTTTTGGTCGTATGAAAGATATTTTCCTGTTTCTTTGGGAAGTGCTCTTTACTAAGCTTTCCCCTCCATCTATATAATTTAATGAGCTTGCCCATCATCAGGGGCTGAGCAATTTGGCAGAACTGCAAATTCTAATTCTGGTCTTGGTACTGAATTGGGGCAAATCACTTAACTTCTGTGTATTCTGTTTTCTTTAGTTGTAAATTGGGAACCAAAAGTTTCATGTTAGCTTTGTGATTAAAAAAAAATAGAGTAAAGCTCTTGCTACAAGTGCTTAGTAAAAGTCAAAATTATTTCTTGCTACAG
Seq C2 exon
ACTCAAATAAAGGATTTGAAAGAGAAACTAGAAGCTGAAAGGACCACTCGAGCCAAGATGGAAAGGGAGAGAGCTGACCTCACCCAAGACCTGGCTGACTTGAATGAGAGGCTGGAGGAGGTAGGAGGATCCAGTTTGGCTCAGCTGGAAATAACTAAGAAACAGGAAACCAAATTCCAGAAGCTGCACCGAGACATGGAAGAGGCCACTCTGCACTTTGAGACAACTTCTGCATCTTTGAAGAAGAGACATGCAGACAGCCTGGCTGAGCTCGAGGGCCAGGTAGAAAATCTACAGCAGGTCAAGCAGAAACTGGAAAAAGACAAGAGTGACTTGCAGCTAGAAGTAGATGACCTCCTGACCCGTGTTGAGCAGATGACAAGAGCTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000144821-MYH15:NM_014981:27
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.677 A=NA C2=0.592
Domain overlap (PFAM):
C1:
PF131661=AAA_13=FE(12.4=100),PF045827=Reo_sigmaC=FE(22.4=100),PF087025=Fib_alpha=FE(26.1=100),PF0157614=Myosin_tail_1=FE(3.5=100)
A:
NA
C2:
PF131661=AAA_13=PD(29.8=55.4),PF045827=Reo_sigmaC=PD(15.7=16.2),PF087025=Fib_alpha=PD(13.9=12.3),PF0157614=Myosin_tail_1=FE(15.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTCAGCTTCAGAAGACGGTT
R:
CCAGTTTCTGCTTGACCTGCT
Band lengths:
349-2299
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)