HsaINT0107649 @ hg19
Intron Retention
Gene
ENSG00000144821 | MYH15
Description
myosin, heavy chain 15 [Source:HGNC Symbol;Acc:31073]
Coordinates
chr3:108129430-108133275:-
Coord C1 exon
chr3:108133079-108133275
Coord A exon
chr3:108129780-108133078
Coord C2 exon
chr3:108129430-108129779
Length
3299 bp
Sequences
Splice sites
5' ss Seq
CAAGTGAGT
5' ss Score
9.1
3' ss Seq
TGGGTGTCCTCCTTTCTCAGGAA
3' ss Score
9.82
Exon sequences
Seq C1 exon
TCCCAGAGTGCCCTGGCCCATGCCCTGCAGAAGGCTCAGCGTGACTGTGACCTTCTACGAGAGCAGTATGAGGAAGAACAAGAGGTCAAGGCTGAGCTGCACCGGACCTTATCCAAAGTCAATGCTGAAATGGTGCAATGGAGAATGAAGTATGAAAACAATGTCATCCAGAGAACAGAAGACTTGGAGGATGCCAA
Seq A exon
GTGAGTAGGGCAAGGCTATCCTTAACCTGGAGTTACTCACATGGAGCAGTATGAGAATAATGACTCTGTCTCCAAGGCCTCATGGTATGCACTTAACAAATCCTTGCCGAGTGCAGGAACAAGCCCAAAACCAAAGCTGAAACGTGCACTGCTGGTAAGAAGCACACTCTGTAGAGGGACTAAAAATATAAAAAGTATAATACAAAGTGACAGAGACTATAAAGAGGTCCTGGGGAGAGAAAGGAGGCTCTTTCTAGGGGCACAAGGGAAGTTTTCATAAAAGATGTGACTTTGAGCCGTGGTGTGAAAATAGGCTATCGTTTAAAACCCTGTATTTCATTTGTAACGCCATAATAATTGAGTCCATGTGTGTACGTGTCTCCATCAAAGTCGTTGTGTCCCTGGTCTACAACTTGTAGACTACAAAGTAGTCTGTGAAGATGGACAGGGAAGCTGGAAAAAAATGTTAGGATCTGTCGTCATGTCTTCTAGGACAAAGGTTGCTTTGAAAAGAAATCATCCCCAGGCCACCCCTAAGATTAGAATATCAATTTTATAGCCATTTCTATGTAAAGGTTTTAAAAGTTTTTAGGAGTTACACAAGTTTGGGGCACAGCTGAATTGAGACTCAGTACCAGGGTATAGAACTGAAGCATTTTGCTTAGAGGCCAGGAAACTGTACCTTTAAGAGAAATTGTCAAACCCCAGCTTATAATCATTCAAGGTTTACTCAAAAGAATGTGTCCCTGGCTTGGTAGCTTGGCAAAAATCCAGGGAAGATCAATACATTTCTCTTTAGCTTCAACCAGAAATAATGTTTTTCAGTTCTTCACCTAAATCTTTGAGAGGCATTGCTGTGCAATTGCTGAACAGCTGCTGTGTTTTGTCCCAGAAGGGGTACCAAGTGATCCATCTCTGTACCCACAGTAACTTAAAAAGGGCTTTAGAATGACAGATACTAAAAATACCTGCAGTAGATGTTTTATCAAAACTCTGGACCACAGAAAGTTTTGGCTTTGAACTGAGATGCCCTCTTATATCCAAATATGGTATTTACTTCTGAAGTAAGATTTTTCCCCCTTCTAATGATTGAAGAATTCAGGTGAAATTGCCTATCTATCATTCTGTTTGATGGTTTCTTTTGGGATTGGGTAGGAAAGAGCAAAAGAATATAGATTACTTTATGACCACATGGGTTTGTTGGAACTAGTTCTGTAGTATGTAATAACTAAAGAAAATAAAGGGCAAACATGGTACTCTGTGAAGACAATTTTTTACTTTCAAATTGGTGGGACATAGAATAAATAAAACTTTGTCTGTATTATGCTTTTCCTCTAAATCACCTCAGGGAGGTAGGCAGCTACAAAACAATCTAGGGTCCTGGTTTCTTTTGTTATTATTAAAGTTAAAGATTTGCCTGCTTTGATTTCCAGGCTGGGGTTCAAATGATGAGTTAGTTTAGCAGACTCAAGCTTATCTAAGACCCATTGTACTGCTTCTGAATTCTAAGTTCCCCAAGGATAAGGATTTAGTTTCTTAATTTCCAATATCCCTTTACATATTCGAGATAACTAAGTAGGTGCTTATGGTTGGCAAGTTAAGGAGCAAAATAGTAGTTGATATTAAACGTAGAACAAAGTTATTGGTAAAACAAGGGTAACCAGTTTGTCCAGTTTGCCCTGGATGTTTCCTGTTTTAGCTTTGAAAGTCTCATGTCCTGGTGTATTAGTCTGTTCTCACACTGCTAATAAAGACATACCCAAGACTGGGTAATTTATAATGGAAAGAGATTTAATTGACTCACAGTTCACCATGGCTGGGGCGACCTCAGGAAACTTACAATCCTGGTGGAAGGGGAAGCAAATAGGTCCTTCTTCACATGGTGGCAGGAAGAGAAGTGAGTGAATAAAAAAGGGGAAAGCCCCTTATAAAACCATCAGATCTCATGAGAACTTACTCGCTGTCATGAGAACAACATGAAGGTTACCGCCTCGATGATTAAATTACCTCCCACTAGTCCCTCCCATGACATGTGGGGATTATGGGAACTACAAGATGAGATTTTGGTGGGGACACAGCCAAACCATATCACCTGGTGAAACCCCTCAGTCCCAGGCAGTCCAGTATGATCAGTCACCCAAAGTGAAACTCCTATTTTATCAACAAGCATTTCTAAAGTAGTTAAAATATATGTAATTATTTCACTTGACTCCTACTGCCTTAAGTCAGGTAAAGCATCAGAATATCCTCTTAACGTTTAAGAAACATGAAGCAGAAAAGTGAAGTGAGTATGGCTAGGAAGCCGGGGGCAGAGTGTTGTTAGAGCCTAGATGCTTCCTGGATCCTGAGCACATAGGGGTTTTTGCAGGATTCCACCAAAAGGGGACTTTATTACCACATTCCTCTGTTGGGCTAGTTATGCAGTCCTATTAATTCCGGAGAACCTTTTTTTCTGTTTAATAGCAGTAGATGAGAAAAAGCTTTGGTACATACAGTACTTTTCATCTAAGAAGTATAATGAATGAGTAAGAATGGGACTGCCAGCAACCCTGCAGGAGATGTAAGAAACAGAACACATTTCATCCATTAGAATTCCTAATAGTAGCATATTACGGGGGTGGTGGAGAAAGAAGCACTGTAATAAATTACTCCATCTCAGAGATGCCCAAGGAACAGCAGATGGGGGCTAAAAAACCCCATAAGAACAGTAGGACCTGTTAAGTGAGCATAATGAGATGGGTTTGGGAATATAAATCTGGAGAGAGGAGCTGAGGTGGAGAACAAACTCGGAGAGAAGAAAGAATTGTGTCATGTTGAGGAGCCACATGATGAGAGAAAATAAGCAGGAAAAAGCAAGAGAGTGTTCTTTAGAAGCAACACAGCCAAGGAGCTCTTTAGTGACTACATATGGCTACAGATTTGTAAGGTGCTTACTGTTGGTAGGGTGTTCAGTACAATCTTCCTTTTCTCCCCCTTCTTAGGAAATAATCAAGTCAGTATTGCTTATTAGAGCTTTAGGATAAGCAAATATTTGTAGGAATTCAAAGAGATTCTGAGTTCCAAGTGCAGGTTGGCAAAGGGGGAAAATAAAGACCCCATGCACACAGGAGGCAGAGGATGGTGGTCATAGACAGTGAGGTCACTTTCAGATAGGAGCTGCTGTTGCTTTATACCACTAAGTCCACTGCAGAGGCGCCATCTTACTTTGCACCCAAGCTCTATCTTTAATCCAGGGCAGACTTGATGAGCTCTCTGAGAGTTATTGCCTCACTCACTCTTTGGGTGTCCTCCTTTCTCAG
Seq C2 exon
GAAGGAACTGGCAATTAGATTGCAGGAGGCAGCCGAAGCCATGGGGGTGGCCAATGCCAGAAATGCCTCCTTGGAGAGAGCCAGGCACCAGCTGCAGCTGGAGCTCGGGGACGCCCTGTCTGACCTCGGGAAGGTCCGCTCTGCAGCAGCCAGGCTGGACCAGAAGCAGCTGCAGTCTGGCAAGGCCCTTGCCGACTGGAAGCAGAAGCACGAGGAGTCCCAGGCGTTGCTGGATGCCTCTCAGAAGGAAGTTCAGGCTCTCAGTACAGAGCTCCTCAAGCTCAAGAACACCTATGAGGAGAGCATCGTGGGCCAGGAGACACTCAGGAGGGAGAACAAGAACCTCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000144821-MYH15:NM_014981:31
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.136 A=NA C2=0.297
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(7.6=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(13.6=100),PF045827=Reo_sigmaC=PU(72.3=90.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)