HsaINT0107716 @ hg19
Intron Retention
Gene
ENSG00000125414 | MYH2
Description
myosin, heavy chain 2, skeletal muscle, adult [Source:HGNC Symbol;Acc:7572]
Coordinates
chr17:10447219-10447444:-
Coord C1 exon
chr17:10447417-10447444
Coord A exon
chr17:10447334-10447416
Coord C2 exon
chr17:10447219-10447333
Length
83 bp
Sequences
Splice sites
5' ss Seq
CACGTAAGT
5' ss Score
10.16
3' ss Seq
ATTGAGTTTTGATTTGACAGTGG
3' ss Score
1.9
Exon sequences
Seq C1 exon
ACCGAGAGAATCAGTCAATCCTGATCAC
Seq A exon
GTAAGTAGATTTTATGCTTTCTTTACATGGCTGTGATAGCTGCTAGGTTTGAGACCACATCTGATTGAGTTTTGATTTGACAG
Seq C2 exon
TGGAGAATCTGGTGCAGGGAAGACTGTGAACACCAAGCGTGTCATCCAGTACTTTGCAACAATTGCAGTTACTGGTGAGAAGAAGAAGGAAGAAATTACTTCTGGCAAAATACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125414-MYH2:NM_001100112:6
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.025 A=NA C2=0.031
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(1.3=100)
A:
NA
C2:
PF0006316=Myosin_head=FE(25.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCGAGAGAATCAGTCAATCCTGA
R:
TGCCAGAAGTAATTTCTTCCTTCT
Band lengths:
135-218
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)