HsaINT0107742 @ hg19
Intron Retention
Gene
ENSG00000109063 | MYH3
Description
myosin, heavy chain 3, skeletal muscle, embryonic [Source:HGNC Symbol;Acc:7573]
Coordinates
chr17:10554829-10555880:-
Coord C1 exon
chr17:10555737-10555880
Coord A exon
chr17:10554986-10555736
Coord C2 exon
chr17:10554829-10554985
Length
751 bp
Sequences
Splice sites
5' ss Seq
TATGTCAGC
5' ss Score
-4.26
3' ss Seq
ATATGTTTTTCCTCCCACAGACC
3' ss Score
11.54
Exon sequences
Seq C1 exon
ACCCTGGTGGTCAAACCAGAGGATGTGTACGCCATGAACCCCCCCAAGTTCGACAGGATCGAAGACATGGCCATGCTGACGCACCTGAATGAGCCAGCCGTGCTGTACAACCTGAAGGACCGTTACACATCTTGGATGATCTAT
Seq A exon
GTCAGCGAGGGCTTTCGACGTGGTTTCCCTGGGGCATTAGATATGCGGGCAGGGGAGGGAGGCAGAGGTATGTGTGTGGGCCGTGGGATTCTGGAAGATGAGTGCTTGCCTAGCTGATGAACAAAACACAAAGACGGAGGAGAAAGAAGGCAAGAAAGCAAGAGGTGGATGGGGCAGGAAGAAGGAAGGTGGGAAGGAGGACCAGGAGCCGGAGAGCGGGGAAGCTGGGGCCAGGCTTGGTCACGGGGTGCTGTGACTTACCAACTGTGGGAGGGTCGCCACTCCCCTTTTTGAGTCTCAGTGCCTCACTATAAATAGGAATGGTAGCCTCCCCCCTTTATAAGTTTATCCCAAAGAAACATGAGATAATAATAAAGGCAGCTGGGTGTGGTGGCTCACGCCCGTAATCCCAGCACTTTGGGAGGGTAAGGCGGGTGGATCATGAGGTCAAGAGATCGAGACCATTCTGGCCAACATGGTGAAGCCCCATCTCTACTAAAATACAAAAATTAGCCGGGCGTGATGGCATGTACCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCCAAGATCGTGCCACTGCACTCCAGCCTGGTGACAGAGTGAGACTCCGTCTCAAAAAAAAAAAAAAACAATAATAATAATAAAGGCAAGGGGTTTTCCATATGCACATACATACATATACGCACGTATATGTTTTTCCTCCCACAG
Seq C2 exon
ACCTACTCAGGCCTCTTCTGTGTCACTGTCAACCCCTACAAGTGGCTGCCGGTGTACAACCCCGAGGTGGTGGAAGGCTACCGAGGCAAAAAGCGCCAGGAGGCCCCACCCCACATCTTCTCCATCTCTGACAACGCCTATCAGTTCATGCTGACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109063-MYH3:NM_002470:3
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.042 A=NA C2=0.057
Domain overlap (PFAM):
C1:
PF0273614=Myosin_N=PD(16.7=14.6),PF0006316=Myosin_head=PU(4.1=58.3)
A:
NA
C2:
PF0006316=Myosin_head=FE(7.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAACCAGAGGATGTGTACGCC
R:
TCAGCATGAACTGATAGGCGT
Band lengths:
286-1037
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)