HsaINT0107742 @ hg38
Intron Retention
Gene
ENSG00000109063 | MYH3
Description
myosin heavy chain 3 [Source:HGNC Symbol;Acc:HGNC:7573]
Coordinates
chr17:10651512-10652563:-
Coord C1 exon
chr17:10652420-10652563
Coord A exon
chr17:10651669-10652419
Coord C2 exon
chr17:10651512-10651668
Length
751 bp
Sequences
Splice sites
5' ss Seq
TATGTCAGC
5' ss Score
-4.26
3' ss Seq
ATATGTTTTTCCTCCCACAGACC
3' ss Score
11.54
Exon sequences
Seq C1 exon
ACCCTGGTGGTCAAACCAGAGGATGTGTACGCCATGAACCCCCCCAAGTTCGACAGGATCGAAGACATGGCCATGCTGACGCACCTGAATGAGCCAGCCGTGCTGTACAACCTGAAGGACCGTTACACATCTTGGATGATCTAT
Seq A exon
GTCAGCGAGGGCTTTCGACGTGGTTTCCCTGGGGCATTAGATATGCGGGCAGGGGAGGGAGGCAGAGGTATGTGTGTGGGCCGTGGGATTCTGGAAGATGAGTGCTTGCCTAGCTGATGAACAAAACACAAAGACGGAGGAGAAAGAAGGCAAGAAAGCAAGAGGTGGATGGGGCAGGAAGAAGGAAGGTGGGAAGGAGGACCAGGAGCCGGAGAGCGGGGAAGCTGGGGCCAGGCTTGGTCACGGGGTGCTGTGACTTACCAACTGTGGGAGGGTCGCCACTCCCCTTTTTGAGTCTCAGTGCCTCACTATAAATAGGAATGGTAGCCTCCCCCCTTTATAAGTTTATCCCAAAGAAACATGAGATAATAATAAAGGCAGCTGGGTGTGGTGGCTCACGCCCGTAATCCCAGCACTTTGGGAGGGTAAGGCGGGTGGATCATGAGGTCAAGAGATCGAGACCATTCTGGCCAACATGGTGAAGCCCCATCTCTACTAAAATACAAAAATTAGCCGGGCGTGATGGCATGTACCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCCAAGATCGTGCCACTGCACTCCAGCCTGGTGACAGAGTGAGACTCCGTCTCAAAAAAAAAAAAAAACAATAATAATAATAAAGGCAAGGGGTTTTCCATATGCACATACATACATATACGCACGTATATGTTTTTCCTCCCACAG
Seq C2 exon
ACCTACTCAGGCCTCTTCTGTGTCACTGTCAACCCCTACAAGTGGCTGCCGGTGTACAACCCCGAGGTGGTGGAAGGCTACCGAGGCAAAAAGCGCCAGGAGGCCCCACCCCACATCTTCTCCATCTCTGACAACGCCTATCAGTTCATGCTGACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109063:ENST00000583535:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.042 A=NA C2=0.057
Domain overlap (PFAM):
C1:
PF0273614=Myosin_N=PD(16.7=14.6),PF0006316=Myosin_head=PU(4.1=58.3)
A:
NA
C2:
PF0006316=Myosin_head=FE(7.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAACCAGAGGATGTGTACGCC
R:
TCAGCATGAACTGATAGGCGT
Band lengths:
286-1037
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development