HsaINT0107803 @ hg19
Intron Retention
Gene
ENSG00000197616 | MYH6
Description
myosin, heavy chain 6, cardiac muscle, alpha [Source:HGNC Symbol;Acc:7576]
Coordinates
chr14:23867937-23869635:-
Coord C1 exon
chr14:23869465-23869635
Coord A exon
chr14:23868247-23869464
Coord C2 exon
chr14:23867937-23868246
Length
1218 bp
Sequences
Splice sites
5' ss Seq
AAGGTGCCT
5' ss Score
5.39
3' ss Seq
CCTCTTCACCCTGCCCTCAGCCC
3' ss Score
8.61
Exon sequences
Seq C1 exon
TTCAACAGCTTTGAGCAGCTCTGCATCAACTTCACCAACGAGAAGCTGCAGCAGTTCTTCAACCACCACATGTTCGTGCTGGAGCAGGAGGAGTACAAGAAGGAGGGCATTGAGTGGACATTCATTGACTTTGGCATGGACCTGCAGGCCTGCATTGACCTCATCGAGAAG
Seq A exon
GTGCCTCCTTGGCCTCACCACCTATGCCCCCTCCTCTGCCATCCAGACAAAGTGGTGGCTGAGTCCCTTCTACACCCAAGAAACTAGAGTCCCAAGAATCCCAGGCCTTTCTCCAGGCCCAGCTTCTCCCCACTGTGAAGTCATGGGCATGAACAGGATGATCCCCCCACTCTTCCTTTCCCAGGACCTTGCACTTTATGCCCCTTTGTGGTGGTCCCCTCAGTGTCTTAAGAGTGAGATGTAGTGAAGGAGAGGCCCCTGGCCCCTCTGACCGCCCATGAGAAGCGTCATTCATGGAAAGATCCTAGGCTGAAATTAGAGATGTTTGGCCTCCCACCACCTTCCTGTTGGTTGAGAAATAAGCCAGTCTCCAGCCCTCTTGCTTATGGGCATTCCTCAGAAGAGACAAGGCCGCAGGCGGGAGGCCCCATAGGCTGGGGCTGACTTGCTCTCAGTGAACCTCTGCTCTTTGTCAGCATAGGCCAGAGCCCGGATTGTCTGACCCACACCCAGCCCAGCCACGGCCTTCATGAAATGGGAGCTTCCCCACATGCTTTGGGTCATTATCCAGATTCTTAACCAGAGTTCTCATGTTTCAGAGCCCTCAGAATGCCATAAAACTGTGTGTGGAAAAAAGCATGTGTACATTCATACATACATGTGTGTGCTTGTGCATGTGTGTGTGTGTACGTGTGTGTGTGTACATGCGTTTTTCTGGAGAGACAGTCTTTAGCTTCAACAAATTCTTAAAAGGATTCCTGCCCCAAGAAAAATCAAGAACCACCAGGTTTTTGGAAGTGCAGAGTGTGGTAAAGAACCTGGATCCTTCTATCTAACCCTTGAAGAATTGCTACTGGTGTCATACAGACAGAGCCTGGCCCGGTGCCTCTGACACACATCTGTCCCTGCCCTCCTGCCCCTGGGGCAGTGAGCCATCAGAGAGAAGGGGCTGTGCTGTGAGGCACTGTGGGCCTTGTGGGGGGTGATTAGGAGTGCATGACTCTTTGTTGGACCCACTGGGCAGAAAGGAGGAGGAAGGGGCTTTTTAAATTCCAGGAATATTGGCTTCCTGTTTTAGGGTAAGAGGTACCAGCACAGCGCCCCTTCAGCAGGCCAGCGCTACTGGCTCCAGATTCCTTTTCCTGTCAGGGTATGGGACTGTGGAAGCCTGGGAGTGTGCTCAGTGATTCTCTCTTTGCCTCTTCACCCTGCCCTCAG
Seq C2 exon
CCCATGGGCATCATGTCCATCCTGGAGGAGGAGTGCATGTTCCCCAAGGCCACTGACATGACCTTCAAGGCCAAGCTGTACGACAACCACCTGGGCAAGTCCAACAATTTCCAGAAGCCACGCAACATCAAGGGGAAGCAGGAAGCCCACTTCTCCCTGATCCACTACGCCGGCACTGTGGACTACAACATCCTGGGCTGGCTGGAAAAAAACAAGGATCCTCTCAACGAGACTGTTGTGGCCCTGTACCAGAAGTCCTCCCTCAAGCTCATGGCCACTCTCTTCTCCTCCTACGCAACTGCCGATACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197616-MYH6:NM_002471:14
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.038
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(8.2=100)
A:
NA
C2:
PF0006316=Myosin_head=FE(15.1=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGAGGGCATTGAGTGGACAT
R:
AGAAGAGAGTGGCCATGAGCT
Band lengths:
357-1575
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)