HsaINT0107856 @ hg38
Intron Retention
Gene
ENSG00000092054 | MYH7
Description
myosin heavy chain 7 [Source:HGNC Symbol;Acc:HGNC:7577]
Coordinates
chr14:23419177-23419609:-
Coord C1 exon
chr14:23419483-23419609
Coord A exon
chr14:23419296-23419482
Coord C2 exon
chr14:23419177-23419295
Length
187 bp
Sequences
Splice sites
5' ss Seq
ATGGTGAGC
5' ss Score
8.27
3' ss Seq
CTAGAATGGTGCTTCCCCAGGTG
3' ss Score
4.6
Exon sequences
Seq C1 exon
GCTAACCTGGAGAAGATGTGCCGGACCTTGGAAGACCAGATGAATGAGCACCGGAGCAAGGCGGAGGAGACCCAGCGTTCTGTCAACGACCTCACCAGCCAGCGGGCCAAGTTGCAAACCGAGAATG
Seq A exon
GTGAGCCTAGAGCAGGGGCTCCATGGTTCCCACCACAGTCTCCCCAACCTCCTGAGCCACTCCAGCCTCGGGCACAAGCCAATACACGCACACACAGACACAGAGTCTCTCCAGAAAATGGGGCCTGAGGGCTAGAGGAGGAGGTGGGGATAGAGAGGAGTGCTGATCTAGAATGGTGCTTCCCCAG
Seq C2 exon
GTGAGCTGTCCCGGCAGCTGGATGAGAAGGAGGCACTGATCTCCCAGCTGACCCGAGGCAAGCTCACCTACACCCAGCAGCTGGAGGACCTCAAGAGGCAGCTGGAGGAGGAGGTTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000092054:ENST00000355349:28
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.860 A=NA C2=0.325
Domain overlap (PFAM):
C1:
PF0003816=Filament=FE(14.8=100),PF0157614=Myosin_tail_1=FE(4.9=100),PF0003816=Filament=PU(4.8=34.9)
A:
NA
C2:
PF0003816=Filament=PD(4.2=30.0),PF0157614=Myosin_tail_1=FE(4.5=100),PF0003816=Filament=FE(12.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTAACCTGGAGAAGATGTGCC
R:
TTAACCTCCTCCTCCAGCTGC
Band lengths:
245-432
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development