HsaINT0107858 @ hg38
Intron Retention
Gene
ENSG00000092054 | MYH7
Description
myosin heavy chain 7 [Source:HGNC Symbol;Acc:HGNC:7577]
Coordinates
chr14:23433084-23433740:-
Coord C1 exon
chr14:23433532-23433740
Coord A exon
chr14:23433228-23433531
Coord C2 exon
chr14:23433084-23433227
Length
304 bp
Sequences
Splice sites
5' ss Seq
AAGGTGGGT
5' ss Score
8.23
3' ss Seq
TTGGGTGGGGGCTCTTGCAGACA
3' ss Score
3.71
Exon sequences
Seq C1 exon
GCACAGCCATGGGAGATTCGGAGATGGCAGTCTTTGGGGCTGCCGCCCCCTACCTGCGCAAGTCAGAGAAGGAGCGGCTAGAAGCGCAGACCAGGCCTTTTGACCTCAAGAAGGATGTCTTCGTGCCTGATGACAAACAGGAGTTTGTCAAGGCCAAGATCGTGTCTCGAGAGGGTGGCAAAGTCACTGCCGAGACCGAGTATGGCAAG
Seq A exon
GTGGGTGTCAGGCTGATGTGAGAGTCCACCCTGGCCACCTGTACACCTGGGTGGACAGAGAGGGGTACACCCATGCCCCATGCCCATGCAGACCTGAGGATGGTCCCATTCTCCTTCCCTTTGGGGAAGAATCCAGACCCTCCAAAGAGCCCTCTCCTTCCCAATATCCCTTCTGTCTTCCCTGTGAGATCCTGGTTCCTTCTCTCTTGAGCACTATTGCCCTGTCACTCACCAACTCCTAACCCTCTTGAGGAAGGAGGGAAAGCCCAGGCTGACAGGAGGGCTTGGGTGGGGGCTCTTGCAG
Seq C2 exon
ACAGTGACCGTGAAGGAGGACCAGGTGATGCAGCAGAACCCACCCAAGTTCGACAAAATCGAGGACATGGCCATGCTGACCTTCCTGCATGAGCCCGCGGTGCTCTACAACCTCAAGGATCGCTACGGCTCCTGGATGATCTAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000092054:ENST00000355349:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.060 A=NA C2=0.146
Domain overlap (PFAM):
C1:
PF0273614=Myosin_N=PU(78.6=49.3)
A:
NA
C2:
PF0273614=Myosin_N=PD(16.7=14.6),PF0006316=Myosin_head=PU(4.1=58.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGGGAGATTCGGAGATGGCA
R:
AGATCATCCAGGAGCCGTAGC
Band lengths:
343-647
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development